Sharda Yadav

Vaxess Technology inc

Rockville, Maryland, United States of America

Research Expertise

Senior Scientist QC

About

SCIENTIFIC PROFILE Experienced analytical biochemist specializing in large biologics (peptides, proteins, and antibodies) and cell-based therapy with a track record of success in basic research, product development, and process optimization. Proven ability to lead projects from conception to completion, driving innovation and efficiency in specific cell and protein production processes. Skilled in applying analytical techniques to characterize and assess the quality of biologic products, ensuring regulatory compliance and meeting quality standards. Seeking a senior-level position where expertise in analytical biochemistry, product development, and process optimization can be leveraged to advance scientific understanding and drive the development of novel therapeutics.

Publications

Dissection of Antibacterial and Toxic Activity of Melittin
Journal of Biological Chemistry
2004
Centrosomal protein CP110 controls maturation of mother centriole during cilia biogenesis
Development
2016
The transcription-splicing protein NonO/p54nrb and three NonO-interacting proteins bind to distal enhancer region and augment rhodopsin expression
Human Molecular Genetics
2013
Utilization of an Amphipathic Leucine Zipper Sequence to Design Antibacterial Peptides with Simultaneous Modulation of Toxic Activity against Human Red Blood Cells
Journal of Biological Chemistry
2006
Regulation of a novel isoform of Receptor Expression Enhancing Protein REEP6 in rod photoreceptors by bZIP transcription factor NRL
Human Molecular Genetics
2014
Identification and Characterization of an Amphipathic Leucine Zipper-like Motif in Escherichia coli Toxin Hemolysin E
Journal of Biological Chemistry
2003
Inhibition of Lytic Activity of Escherichia coli Toxin Hemolysin E against Human Red Blood Cells by a Leucine Zipper Peptide and Understanding the Underlying Mechanism
Biochemistry
2008
Phosphorylation, Dephosphorylation, and Multiprotein Assemblies Regulate Dynamic Behavior of Neuronal Cytoskeleton: A Mini-Review
Frontiers in Molecular Neuroscience
2018
Addition of a small hydrophobic segment from the head region to an amphipathic leucine zipper like motif of E. coli toxin hemolysin E enhances the peptide-induced permeability of zwitterionic lipid vesicles
Biochimica et Biophysica Acta (BBA) - Biomembranes
2007
A peptide derived from the putative transmembrane domain in the tail region of E. coli toxin hemolysin E assembles in phospholipid membrane and exhibits lytic activity to human red blood cells: Plausible implications in the toxic activity of the protein
Biochimica et Biophysica Acta (BBA) - Biomembranes
2009
TP5: A Novel Therapeutic Approach Targeting Aberrant and Hyperactive CDK5/p25 for the Treatment of Colorectal Carcinoma
International Journal of Molecular Sciences
2023
Protein kinase CK2 modulates the activity of Maf-family bZIP transcription factor NRL in rod photoreceptors of mammalian retina
Human Molecular Genetics
2022
Peptides Derived from Neuronal Cell Cycle like Kinase 5 Activator p35, in Neurodegeneration; Pathology and Therapy
Journal of Alzheimer’s Disease & Parkinsonism
2017
Backmatter
Sites of Knowledge
2015
Monitoring of Strain-Dependent Responsiveness to TLR Activation in the Mouse Anterior Segment Using SD-OCT
Investigative Ophthalmology & Visual Science
2014
Rod Outer Segment Retinol Formation Is Independent of Abca4, Arrestin, Rhodopsin Kinase, and Rhodopsin Palmitylation
Investigative Ophthalmology & Visual Science
2011
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