Manager, Cell Culture Production, Upstream Manufacturing / June, 2019 — March, 2023

Responsible for performing/supervising cell culture maintenance and media/supplement preparation for cGMP manufacturing while practicing strong aseptic technique Responsible for generating and revising batch records, SOPs and other cGMP documents as necessary Directly supervise two upstream manufacturing specialists and 2 manufacturing scientists Report to Director of Upstream Manufacturing Represented Upstream Manufacturing as Seed Lab SME during 2 FDA Inspections and ultimate FDA approval

Senior Scientist II, Cell Culture Production, Upstream Manufacturing / June, 2016 — June, 2019

Responsible for performing/supervising cell culture maintenance and media/supplement preparation for cGMP manufacturing while practicing strong aseptic technique Responsible for generating and revising batch records, SOPs and other cGMP documents as necessary

Senior Scientist II, Preclinical Development / July, 2013 — May, 2016

Design, perform and analyzes cell-based assays to determine in vitro functional characterization and mechanism of action of monoclonal antibodies, which includes conducting CDC, ADCC, cell signaling (e.g., Western blots, etc.), apoptosis, and anti-proliferative analyses (e.g., MTS, etc.) Processing of human blood (e.g., isolation of T cell subsets, etc.) from blood banks and in-house donors for use in cell-based assays (e.g., T-cell redirecting assays, ADCC, etc.) Multicolor FACs analysis Manuscript preparation and associated publications Report to Director of Preclinical Development

Senior Scientist, Research & Development / July, 2006 — July, 2013

Design of expression vectors for production of novel recombinant proteins Development of strategies for the production, purification, biochemical characterization and evaluation of biological activity Cell line and assay development Manuscript preparation and associated publications Presentation of results at scientific meetings Report to VP of R&D

Scientist, Research & Development / October, 2005 — June, 2006

Construction of humanized antibody staging and expression vectors for the production of novel recombinant proteins Transfection of humanized expression vectors using mammalian expression system Selection, screening, subcloning and amplification of stable antibody producing cell lines Antibody purification and characterization (BIAcore, HPLC, SDS-PAGE, Western Blot, etc.) Cell based assays (ADCC, MTT, etc.) Development and characterization of novel mammalian host cell line Design and perform experiments such as in vitro assays and optimization of purification procedures Lead in bench-scale bioreactor experiments for medium development, cell line screening and cell culture process development Report to VP of R&D