Work with Elizabeth Martin | NotedSource
A biomedical researcher with 20 years of experience in
discovering signaling networks altered in human diseases.
Specializing in vitro, in vivo, and cell-based assays for
drug and biomarker discovery. A strong track record of
leading research teams in the evaluation of protein
targets involved in cancer drug resistance and stem cell
function.
https://cv.notedsource.io/me/25JNPN3R
Elizabeth Martin
A biomedical researcher with 20 years of experience in discovering signaling networks altered in human diseases.
Research Expertise
Endocrinology, Diabetes and Metabolism
Endocrinology
Oncology
Histology
Biomedical Engineering
Biotechnology
Bioengineering
Biochemistry
Cancer Research
Molecular Biology
Cell Biology
Structural Biology
Biophysics
Genetics
Metals and Alloys
Biomaterials
Ceramics and Composites
Molecular Medicine
Development
Anatomy
Clinical Biochemistry
Physiology
Physiology (medical)
Neurology (clinical)
Neurology
Psychiatry and Mental health
Rehabilitation
Hematology
Advanced and Specialized Nursing
Maternity and Midwifery
Obstetrics and Gynecology
Public Health, Environmental and Occupational Health
Developmental Biology
Pharmacology
Genetics (clinical)
Transplantation
Immunology
Immunology and Allergy
Atomic and Molecular Physics, and Optics
Condensed Matter Physics
Electrical and Electronic Engineering
Industrial and Manufacturing Engineering
Inorganic Chemistry
Catalysis
Organic Chemistry
Computer Science Applications
Physical and Theoretical Chemistry
Spectroscopy
Epidemiology
Materials Chemistry
Economics and Econometrics
Media Technology
Forestry
About
A biomedical researcher with 20 years of
experience in discovering signaling networks
altered in human diseases. Specializing in
vitro, in vivo, and cell-based assays for drug
and biomarker discovery. A strong track record
of leading research teams in the evaluation of
protein targets involved in cancer drug
resistance and stem cell function.
Legacy Map
Full ViewPublications
Stromal cells and stem cells in clinical
bone regeneration
Nature Reviews Endocrinology
2015
Endocrine Disruptor Regulation of MicroRNA
Expression in Breast Carcinoma Cells
PLoS ONE
2012
Proteomic analysis of acquired tamoxifen
resistance in MCF-7 cells reveals
expression signatures associated with
enhanced migration
Breast Cancer Research
2012
Dual regulation by microRNA-200b-3p and
microRNA-200b-5p in the inhibition of
epithelial-to-mesenchymal transition in
triple-negative breast cancer
Oncotarget
2015
Engineering Breast Cancer
Microenvironments and 3D Bioprinting
Frontiers in Bioengineering and
Biotechnology
2018
The histone deacetylase inhibitor
trichostatin A alters microRNA expression
profiles in apoptosis-resistant breast
cancer cells
Oncology Reports
2011
MicroRNA regulation of stem cell
differentiation and diseases of the bone
and adipose tissue: Perspectives on miRNA
biogenesis and cellular transcriptome
Biochimie
2016
Preferential star strand biogenesis of
pre‐miR‐24‐2 targets PKC‐alpha and
suppresses cell survival in MCF‐7 breast
cancer cells
Molecular Carcinogenesis
2012
Endocrine disruptors and the tumor
microenvironment: A new paradigm in breast
cancer biology
Molecular and Cellular
Endocrinology
2017
MEK5/ERK5 Signaling Suppresses Estrogen
Receptor Expression and Promotes
Hormone-Independent Tumorigenesis
PLoS ONE
2013
Regulation of triple-negative breast
cancer cell metastasis by the
tumor-suppressor liver kinase B1
Oncogenesis
2015
MicroRNA‐335‐5p and ‐3p synergize to
inhibit estrogen receptor alpha expression
and promote tamoxifen resistance
FEBS Letters
2017
Inhibition of p38 mitogen-activated
protein kinase alters microRNA expression
and reverses epithelial-to-mesenchymal
transition
International Journal of Oncology
2013
Comparative proteomic analyses of human
adipose extracellular matrices
decellularized using alternative
procedures
Journal of Biomedical Materials
Research Part A
2018
Transcriptomic Profiling of Adipose
Derived Stem Cells Undergoing Osteogenesis
by RNA-Seq
Scientific Reports
2019
Altered Death Receptor Signaling Promotes
Epithelial-to-Mesenchymal Transition and
Acquired Chemoresistance
Scientific Reports
2012
microRNA regulation of mammalian target of
rapamycin expression and activity controls
estrogen receptor function and RAD001
sensitivity
Molecular Cancer
2014
Insulin-Like Growth Factor-1 Signaling
Regulates miRNA Expression in MCF-7 Breast
Cancer Cell Line
PLoS ONE
2012
miR-155 induced transcriptome changes in
the MCF-7 breast cancer cell line leads to
enhanced mitogen activated protein kinase
signaling
Genes & Cancer
2014
Evaluation of intercellular communication
between breast cancer cells and
adipose-derived stem cells
via passive diffusion in a
two-layer microfluidic device
Lab on a Chip
2020
Drug resistance profiling of a new triple
negative breast cancer patient-derived
xenograft model
BMC Cancer
2019
A novel patient-derived xenograft model
for claudin-low triple-negative breast
cancer
Breast Cancer Research and
Treatment
2018
Lignin-graft-PLGA drug-delivery system
improves efficacy of MEK1/2 inhibitors in
triple-negative breast cancer cell line
Nanomedicine
2020
Panobinostat suppresses the mesenchymal
phenotype in a novel claudin-low triple
negative patient-derived breast cancer
model
Oncoscience
2018
The Relative Functionality of Freshly
Isolated and Cryopreserved Human
Adipose-Derived Stromal/Stem Cells
Cells Tissues Organs
2016
Glyceollin, a novel regulator of
mTOR/p70S6 in estrogen receptor positive
breast cancer
The Journal of Steroid Biochemistry and
Molecular Biology
2015
Evaluation of Extracellular Matrix
Composition to Improve Breast Cancer
Modeling
Tissue Engineering Part A
2021
A Role for Adipocytes and Adipose Stem
Cells in the Breast Tumor Microenvironment
and Regenerative Medicine
Frontiers in Physiology
2021
Evaluation of deacetylase inhibition in
metaplastic breast carcinoma using
multiple derivations of preclinical models
of a new patient-derived tumor
PLOS ONE
2020
ERK5 Is Required for Tumor Growth and
Maintenance Through Regulation of the
Extracellular Matrix in Triple Negative
Breast Cancer
Frontiers in Oncology
2020
Argonaute 2 Expression Correlates with a
Luminal B Breast Cancer Subtype and
Induces Estrogen Receptor Alpha Isoform
Variation
Non-Coding RNA
2016
In-depth characterization of a new
patient-derived xenograft model for
metaplastic breast carcinoma to identify
viable biologic targets and patterns of
matrix evolution within rare tumor types
Clinical and Translational
Oncology
2021
The effect of obesity on adipose-derived
stromal cells and adipose tissue and their
impact on cancer
Cancer and Metastasis Reviews
2022
Quantifying Breast Cancer-Driven Fiber
Alignment and Collagen Deposition in
Primary Human Breast Tissue
Frontiers in Bioengineering and
Biotechnology
2021
Trauma induced heterotopic ossification
patient serum alters mitogen activated
protein kinase signaling in adipose stem
cells
Journal of Cellular Physiology
2018
Mirna biogenesis pathway is differentially
regulated during adipose derived
stromal/stem cell differentiation
Adipocyte
2018
Phase II study of single-agent bosutinib,
a Src/Abl tyrosine kinase inhibitor, in
patients with locally advanced or
metastatic breast cancer pretreated with
chemotherapy
Annals of Oncology
2012
Self‐injurious behaviours in rhesus
macaques: Potential glial mechanisms
Journal of Intellectual Disability
Research
2018
Generation of 3D Spheroids Using a
Thiol–Acrylate Hydrogel Scaffold to Study
Endocrine Response in ER+
Breast Cancer
ACS Biomaterials Science &
Engineering
2022
Patient-Derived Xenografts as an
Innovative Surrogate Tumor Model for the
Investigation of Health Disparities in
Triple Negative Breast Cancer
Women's Health Reports
2020
Acellular Biologic Nipple–Areolar Complex
Graft: In Vivo Murine and Nonhuman
Primate Host Response Evaluation
Tissue Engineering Part A
2020
Adipose-Derived Stromal/Stem Cell Response
to Tumors and Wounds: Evaluation of
Patient Age
Stem Cells and Development
2022
Modeling Breast Cancer in Human Breast
Tissue using a Microphysiological System
Journal of Visualized Experiments
2021
Breast Cancer-Stromal Interactions:
Adipose-Derived Stromal/Stem Cell Age and
Cancer Subtype Mediated Remodeling
Stem Cells and Development
2022
microRNA Sequencing of CD34+ Sorted
Adipose Stem Cells Undergoing
Endotheliogenesis
Stem Cells and Development
2021
Comparative Analysis of Human
Adipose-Derived Stromal/Stem Cells and
Dermal Fibroblasts
Stem Cells and Development
2021
Breast Cancer Reconstruction: Design
Criteria for a Humanized
Microphysiological System
Tissue Engineering Part A
2021
Adipose-Derived Stem/Stromal Cells
Regenerative Medicine - from Protocol
to Patient
2016
LKB1 signaling and patient survival
outcomes in hepatocellular carcinoma
Pharmacological Research
2023
Liver Kinase B1 Regulates Remodeling of
the Tumor Microenvironment in
Triple-Negative Breast Cancer
Frontiers in Molecular
Biosciences
2022
Application of a small molecule inhibitor
screen approach to identify CXCR4
downstream signaling pathways that promote
a mesenchymal and fulvestrant‑resistant
phenotype in breast cancer cells
Oncology Letters
2021
Proteomic characterization of a
trauma-based rat model of heterotopic
ossification identifies interactive
signaling networks as potential
therapeutic targets
Journal of Proteomics
2020
Using an in vitro fluidics approach
to model the evolution of metastatic
breast cancer reveals shear stress as a
possible driver of genomic instability and
somatic mutation
The FASEB Journal
2019
Age-dependent modulation of the
extracellular microenvironment of human
adipose-derived stem cells
Cytotherapy
2018
Abstract 3906: Ex vivo breast
tumors for understanding the patient
specific tumor microenvironment remodeling
and drug responses
Cancer Research
2024
A modular microfluidic platform to study
how fluid shear stress alters estrogen
receptor phenotype in ER+ breast cancer
cells
Microsystems &
Nanoengineering
2024
Enhanced Angiogenesis in HUVECs
Preconditioned with Media from Adipocytes
Differentiated from Lipedema Adipose Stem
Cells In Vitro
International Journal of Molecular
Sciences
2023
A modular microfluidic platform to study
how fluid shear stress alters estrogen
receptor phenotype in ER+ breast cancer
cells
Unknown Venue
2023
Co-culture of Two Different Cell Lines in
a Two-Layer Microfluidic Device
Methods in Molecular Biology
2022
Abstract 282: Breast cancer
microphysiological systems based on human
breast tissue
Cancer Research
2022
Abstract 3831: Utilizing decellularized
triple-negative breast cancer
patient-derived tumor models as drug
testing platforms
Cancer Research
2022
235 Analysiss of TNBC Cell Lines Cultured
a Novel Translational Breast Cancer
Microphysiological System (BC-MPS)
Journal of Clinical and Translational
Science
2022
Abstract P5-02-03: Phenotypic analysis for
TNBC using a novel breast cancer
microphysiological system
Cancer Research
2022
Abstract P3-01-16: Utilizing a
decellularized patient-derived xenograft
tumor model for the evaluation of triple
negative breast cancer
Cancer Research
2020
Commonwealth Bank - Head Office cnr Pitt
Street & Martin Place - Construction -
View from Martin Place (Street level) - 18
April 1916 (plate 630)
Unknown Venue
2021
Abstract 80: Utilizing a decellularized
PDX tumor matrix model to investigate LKB1
regulation of ECM remodeling in TNBC
Cancer Research
2021
Correction: Evaluation of deacetylase
inhibition in metaplastic breast carcinoma
using multiple derivations of preclinical
models of a new patient-derived tumor
PLOS ONE
2021
Abstract C110: Applications of
patient-derived triple-negative breast
cancer xenografts that represent
understudied patients in Louisiana in
targeted therapeutic research
Cancer Epidemiology, Biomarkers &
Prevention
2020
Abstract P6-03-17: Effect of histone
deacetylase inhibitors on patient-derived
neoadjuvant chemotherapy resistant triple
negative breast cancer xenografts that
represent understudied patients
Cancer Research
2020
Abstract A105: Novel lignin-conjugated
PLGA drug delivery system improves
efficacy of MEK1/2 inhibitor in triple
negative breast cancer
Molecular Cancer Therapeutics
2019
Adaptable microfluidic device improves the
measurement of cancer cell migration and
trapping
Scilight
2019
Abstract 4236: Evaluating alterations in
mRNA biogenesis with TCGA breast cancer
sequencing data
Cancer Research
2019
Abstract 1385: In vitro evaluation
of platinum chemotherapy combinations with
the ATR inhibitor, ceralasertib (AZD6738)
Cancer Research
2020
Abstract A01: Application of
patient-derived models from understudied
patient populations to discover
therapeutically targetable pathways in
triple-negative breast cancer systems
Molecular Cancer Research
2018
Abstract 4410: ZEB2 drives cell motility
and metastasis in ER+ breast cancer cells
through a novel, E-cadherin independent
pathway
Cancer Research
2016
Abstract 1596: Induction of
mesenchymal-to-epithelial transition
through pan-MEK inhibition in
triple-negative breast cancer
Cancer Research
2016
Abstract 5096: Development of a
decellularized tumor model for the
evaluation of breast carcinomas
Cancer Research
2016
Abstract 1571: The tumor suppressor Liver
Kinase B1 inhibits triple-negative breast
cancer cell metastasis via regulation of
AP-1 signaling
Cancer Research
2014
Abstract 1052: Dual role of MEK1/2 and
MEK5 in the reversal of
epithelial-to-mesenchymal transition
Cancer Research
2014
Abstract 1034: ZEB2 promotes cell motility
and metastasis in ER+ breast cancer cells
Cancer Research
2014
Tulane/Xavier Vaccine Peptide Program
Unknown Venue
2013
Education
Tulane University
PhD, Biomedical Sciences / December, 2013
New Orleans, Louisiana, United
States of America
Experience
Louisiana State University
Assistant Professor Biological Engineering / 2016 — 2022
Tulane University
Associate Professor / 2023 — Present
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