Brittan S. Scales, M.P.H, Ph.D.

Highly skilled Bioinformatician and Microbiologist trained in Microbiome and NGS research

Research Expertise

microbiomes
marine plastic biofilms
genomics
next-generation sequencing
bioinformatics
Microbiology (medical)
Infectious Diseases
Public Health, Environmental and Occupational Health
Epidemiology
Pathology and Forensic Medicine
Immunology and Allergy
Cell Biology
Immunology
Virology
Microbiology
Molecular Biology
Biotechnology
Genetics
Pulmonary and Respiratory Medicine
Critical Care and Intensive Care Medicine

About

Dr. Brittan S. Scales is a highly educated and experienced microbiologist and immunologist with a passion for infectious diseases and public health. She received her Ph.D. in Microbiology and Immunology from the University of Michigan–Ann Arbor in 2015, where she focused on studying the interactions between the lung microbiome and immune response. She also obtained her Master of Public Health degree in Infectious Diseases and Vaccinology from the University of California, Berkeley, in 2009. After completing her Ph.D., Dr. Scales worked as a Postdoctoral Researcher at the University of Michigan's Department of Microbiology & Immunology and the Leibniz Institute for Baltic Sea Research in Germany. Her research during this time focused on understanding the role of microbes in the environment and their impact on human health. Most recently, Dr. Scales worked as a Ph.D. Production Expert at ScaleAI, where she utilized her expertise in coding, math, and science to develop software solutions for various industries. She also continues to conduct research and publish papers in the fields of microbiology and immunology. Dr. Scales is dedicated to using her knowledge and skills to contribute to the prevention and treatment of infectious diseases and promote public health. She is a highly sought-after expert in her field and is committed to making a positive impact in the scientific community and beyond.

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Publications

Microbiology, Genomics, and Clinical Significance of the Pseudomonas fluorescens Species Complex, an Unappreciated Colonizer of Humans
Clinical Microbiology Reviews
2014
Changes in the Lung Microbiome following Lung Transplantation Include the Emergence of Two Distinct Pseudomonas Species with Distinct Clinical Associations
PLoS ONE
2014
The microbiome in wound repair and tissue fibrosis
The Journal of Pathology
2012
A tale of two sites: how inflammation can reshape the microbiomes of the gut and lungs
Journal of Leukocyte Biology
2016
Vibrio Colonization Is Highly Dynamic in Early Microplastic-Associated Biofilms as Well as on Field-Collected Microplastics
Microorganisms
2020
Cross-Hemisphere Study Reveals Geographically Ubiquitous, Plastic-Specific Bacteria Emerging from the Rare and Unexplored Biosphere
mSphere
2021
Comparative genomics of Pseudomonas fluorescens subclade III strains from human lungs
BMC Genomics
2015
Genome Sequences of 12 Pseudomonas lundensis Strains Isolated from the Lungs of Humans
Genome Announcements
2018
Draft Genome Sequences of Five Pseudomonas fluorescens Subclade I and II Strains, Isolated from Human Respiratory Samples
Genome Announcements
2015
Draft Genome Sequences of Seven Pseudomonas fluorescens Subclade III Strains Isolated from Cystic Fibrosis Patients
Genome Announcements
2015
The Psychrotrophic Pseudomonas lundensis, a Non- aeruginosa Pseudomonad, Has a Type III Secretion System of the Ysc Family, Which Is Transcriptionally Active at 37°C
mBio
2022
Expression of Concern: Alveolar Macrophages from Overweight/Obese Subjects with Asthma Demonstrate a Proinflammatory Phenotype
American Journal of Respiratory and Critical Care Medicine
2015
Analysis of Culture-Dependent versus Culture-Independent Techniques for Identification of Bacteria in Clinically Obtained Bronchoalveolar Lavage Fluid
Journal of Clinical Microbiology
2014
The Lung Microbiome Predicts Mortality and Response to Azithromycin in Lung Transplant Patients with Chronic Rejection
American Journal of Respiratory and Critical Care Medicine
2024
Next Steps for Confirming Bronchoalveolar Lavage Amlyase as an Useful Biomarker for Ventilator-Associated Pneumonia*
Critical Care Medicine
2018

Education

University of Michigan–Ann Arbor

Ph.D., Microbiology and Immunology / September, 2015

Ann Arbor, Michigan, United States of America

University of California, Berkeley

M.P.H, Infectious Diseases and Vaccinology / May, 2009

Berkeley, California, United States of America

University of California, Los Angeles

B.S., Microbiology, Immunology & Molecular Genetics / April, 2006

Los Angeles, California, United States of America

Experience

ScaleAI

Ph.D. Production Expert, Coding/Math/Science / February, 2023March, 2024

Train a proprietary AI model on the subjects of coding, science, and math.

Leibniz Institute for Baltic Sea Research, Warnemünde (IOW)

Postdoctoral Researcher / July, 2018November, 2022

Principal researcher for two large international projects. Optimized protocols and pipelines for the sequencing of microbial sequences from mixed trophic aquatic environments. DNA extraction, PCR, molecular methods, NGS, bioinformatic analysis. Analysis and interpretation of targeted metabolomics data using HPLC-UV/Vis and MS. Data storage, organization, and maintenance. Created, organized, and maintained an extensive microbial culture collection. Coordinated international logistics with an inter-disciplinary team. Wrote progress reports and translated official documents between German and English. Presented results to interdisciplinary audiences at the local and international level. Published results in high-impact, peer-reviewed scientific research journals. Supervised and trained student interns and technicians. Prepared protocols and materials for a large, tran-Pacific research cruise. Oversaw day-to-day operations, making sure to maintain a high level of quality assurance.

University of Michigan, Department of Microbiology & Immunology

Postdoctoral Researcher / January, 2016June, 2018

Designed RNA-Seq experiments to track microbial gene expression in response to environmental conditions relevant to mammalian host infection. Performed RNA extraction protocols. Mapped phylogenetic relatedness of a new subclade of microorganisms using next-generation sequencing methods.

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