Mohammad Nizam Mansoori

CSIR-CDRI

Research Expertise

Immunology
Cellular and Molecular Neuroscience
Cell Biology
Cancer Research
Endocrinology, Diabetes and Metabolism
Orthopedics and Sports Medicine
Biochemistry
Molecular Biology
Pharmacology
Obstetrics and Gynecology
Physiology
Histology
Immunology and Allergy
Complementary and alternative medicine
Drug Discovery
Pharmaceutical Science
Molecular Medicine
Endocrinology
Radiology, Nuclear Medicine and imaging

Publications

Estrogen Deficiency Induces the Differentiation of IL-17 Secreting Th17 Cells: A New Candidate in the Pathogenesis of Osteoporosis
PLoS ONE
2012
miR-542-3p suppresses osteoblast cell proliferation and differentiation, targets BMP-7 signaling and inhibits bone formation
Cell Death & Disease
2014
Enhanced Immunoprotective Effects by Anti-IL-17 Antibody Translates to Improved Skeletal Parameters Under Estrogen Deficiency Compared With Anti-RANKL and Anti-TNF-α Antibodies
Journal of Bone and Mineral Research
2014
IL-18BP is decreased in osteoporotic women: Prevents Inflammasome mediated IL-18 activation and reduces Th17 differentiation
Scientific Reports
2016
Interleukin 27 (IL-27) Alleviates Bone Loss in Estrogen-deficient Conditions by Induction of Early Growth Response-2 Gene
Journal of Biological Chemistry
2017
Medicarpin, a Natural Pterocarpan, Heals Cortical Bone Defect by Activation of Notch and Wnt Canonical Signaling Pathways
PLOS ONE
2015
Pioglitazone-induced bone loss in diabetic rats and its amelioration by berberine: A portrait of molecular crosstalk
Biomedicine & Pharmacotherapy
2017
Methoxyisoflavones formononetin and isoformononetin inhibit the differentiation of Th17 cells and B-cell lymphopoesis to promote osteogenesis in estrogen-deficient bone loss conditions
Menopause
2016
Efficacy of anti-IL-23 monotherapy versus combination therapy with anti-IL-17 in estrogen deficiency induced bone loss conditions
Bone
2018
Medicarpin prevents arthritis in post-menopausal conditions by arresting the expansion of TH17 cells and pro-inflammatory cytokines
International Immunopharmacology
2020
Combination of PTH (1-34) with anti-IL17 prevents bone loss by inhibiting IL-17/N-cadherin mediated disruption of PTHR1/LRP-6 interaction
Bone
2017
Ethanolic extract of Coelogyne cristata Lindley (Orchidaceae) and its compound coelogin promote osteoprotective activity in ovariectomized estrogen deficient mice
Phytomedicine
2014
Potential osteogenic activity of ethanolic extract and oxoflavidin isolated from Pholidota articulata Lindley
Journal of Ethnopharmacology
2015
3-Piperidylethoxypterocarpan: A potential bone anabolic agent that improves bone quality and restores trabecular micro-architecture in ovariectomized osteopenic rats
Molecular and Cellular Endocrinology
2017
Journal of Bone and Mineral Research: Volume 34, Number 12, December 2019
Journal of Bone and Mineral Research
2019
Locally applied simvastatin promotes fracture healing in ovariectomized rat: a novel molecular mechanism
Osteoporosis International
2008
miR-376c Targets ArfGEFs (ADP-Ribosylation Factor Nucleotide-Exchange Factor 1; Brefeldin A-Inhibited) to Negatively Regulate Osteoblast Differentiation
Journal of Clinical Densitometry
2014

Experience

NIH/NIAID

November, 2017November, 2023

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