Luca Delfinis

PhD candidate in physiology researching the mechanisms that drive muscle dysfunction in cancer

Toronto, Ontario, Canada

Research Expertise

Physiology

Physiology (medical)

Cell Biology

About

Luca Delfinis is a PhD candidate at York University where his research focuses on muscle dysfunction in cancer. Luca has been a part of several research collaborations both nationally and internationally throughout his PhD that has helped him gain unique perspectives in physiology, especially in the context of metabolism. He has also presented at several conferences where he has discussed data with leaders in cachexia, metabolism, exercise and more.

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Publications

Muscle weakness precedes atrophy during cancer cachexia and is linked to muscle-specific mitochondrial stress

JCI Insight

2022

Mitochondrial bioenergetic dysfunction in the D2.mdx model of Duchenne muscular dystrophy is associated with microtubule disorganization in skeletal muscle

PLOS ONE

2020

Early myopathy in Duchenne muscular dystrophy is associated with elevated mitochondrial H ₂ O ₂ emission during impaired oxidative phosphorylation

Journal of Cachexia, Sarcopenia and Muscle

2019

Mitochondrial creatine sensitivity is lost in the D2.mdx model of Duchenne muscular dystrophy and rescued by the mitochondrial-enhancing compound Olesoxime

American Journal of Physiology-Cell Physiology

2023

Education

Wilfrid Laurier University

BSc, Kinesiology & Physical Education / April, 2018

Waterloo, Ontario, Canada

York University

MSc, Molecular, Cellular and Integrative Physiology / August, 2020

Toronto, Ontario, Canada

York University

PhD, Molecular, Cellular and Integrative Physiology / August, 2024 (anticipated)

Toronto, Ontario, Canada

Experience

York University

Teaching Assistant / September, 2018 — Present

KINE 2049 (Research Methods in Kinesiology) and KINE 3012 (Human Physiology II)

Wilfrid Laurier University

Supplemental Instruction Senior Mentor / April, 2017 — April, 2018

Oversee teaching assistants with their teaching programs

Links & Social Media

ResearchGate

LinkedIn

Twitter

Google Scholar

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