John Bilello Ph.D.

Principal and Consultant at Innovalyst ICAN

About

Dr. John Bilello has over 25 years of experience in the pharmaceutical industry, the biotechnology sector, and academic and government laboratories. He was an Associate Professor at the University of Maryland School of Medicine and Albany Medical College. Dr. Bilello joined GlaxoSmithKline (GSK), where he was the Director of Technology Development in Translational Medicine and Genetics. John assessed external technologies in his technology development role, identifying new investment opportunities for GSK’s Technology Investment Board. His work with GSK’s Human Biomarker Laboratories led to tools for stratifying patients and monitoring efficacy in clinical studies. Specifically, he developed biomarkers for enabling studies of new therapeutics for COPD, diabetes/metabolic syndrome, migraine, and neurodegenerative diseases. Before joining GSK, he was a biochemist at Roche Pharmaceuticals, a Volkswagen Fellow at the University of Hamburg (Germany), and the Director of Preclinical Research and Development at two successful biotechnology companies (SRA Lifesciences and Virco Laboratories). As an enthusiastic entrepreneur, John was a founder and Chief Scientific Officer of Ridge Diagnostics, which developed and commercialized a diagnostic for major depressive disorder. At Ridge, he was an inventor on multiple US and international patents and processes. John has authored over seventy publications in refereed journals and more than ten book chapters. An internationally recognized scientist, he was a member of the editorial board for *Antimicrobial Agents and Chemotherapy* (1995-2009). In addition to an established track record of innovative basic and clinical research, Dr. Bilello has extensive experience in project and organizational management. John was a co-founder and Managing Partner of Innovalyst LLC,  a small business accelerator focused on catalyzing product innovation in the Life Sciences.

Publications

(132) Use of a depression biomarker panel to diagnose depression in chronic pain patients

The Journal of Pain / Apr 01, 2015

Tennant, F., Bilello, J., & Thurmond, L. (2015). (132) Use of a depression biomarker panel to diagnose depression in chronic pain patients. The Journal of Pain, 16(4), S9. https://doi.org/10.1016/j.jpain.2015.01.046

MDDScore

The Journal of Clinical Psychiatry / Feb 25, 2015

Bilello, J. A., Thurmond, L. M., Smith, K. M., Pi, B., Rubin, R., Wright, S. M., Taub, F., Henry, M. E., Shelton, R. C., & Papakostas, G. I. (2015). MDDScore: Confirmation of a Blood Test to Aid in the Diagnosis of Major Depressive Disorder. The Journal of Clinical Psychiatry, 76(02), e199–e206. https://doi.org/10.4088/jcp.14m09029

MDDScore and Biomarker Profiling in Patients Treated with Transcranial Magnetic Stimulation: Preliminary Data

Brain Stimulation / Sep 01, 2014

Bilello, J. A., Thurmond, L. M., Vaishnavi, S., & Kinback, K. M. (2014). MDDScore and Biomarker Profiling in Patients Treated with Transcranial Magnetic Stimulation: Preliminary Data. Brain Stimulation, 7(5), e17. https://doi.org/10.1016/j.brs.2014.07.002

The diagnosis of depression: current and emerging methods

Comprehensive Psychiatry / Jan 01, 2013

Smith, K. M., Renshaw, P. F., & Bilello, J. (2013). The diagnosis of depression: current and emerging methods. Comprehensive Psychiatry, 54(1), 1–6. https://doi.org/10.1016/j.comppsych.2012.06.006

Development of novel approaches to the evaluation of virucidal agents: separation of treated virions from test compounds

AIDS / Feb 01, 2001

Bilello, J., Belay, S., & Weislow, O. S. (2001). Development of novel approaches to the evaluation of virucidal agents: separation of treated virions from test compounds. AIDS, 15, S39. https://doi.org/10.1097/00002030-200102001-00056

The Triple Combination Indinavir-Zidovudine-Lamivudine Is Highly Synergistic

Antimicrobial Agents and Chemotherapy / Apr 01, 2000

Snyder, S., D’Argenio, D. Z., Weislow, O., Bilello, J. A., & Drusano, G. L. (2000). The Triple Combination Indinavir-Zidovudine-Lamivudine Is Highly Synergistic. Antimicrobial Agents and Chemotherapy, 44(4), 1051–1058. https://doi.org/10.1128/aac.44.4.1051-1058.2000

A 24-week open-label Phase I/II evaluation of the HIV protease inhibitor MK-639 (indinavir)

AIDS / May 01, 1996

Stein, D. S., Fish, D. G., Bilello, J. A., Preston, S. L., Martineau, G. L., & Drusano, G. L. (1996). A 24-week open-label Phase I/II evaluation of the HIV protease inhibitor MK-639 (indinavir). AIDS, 10(5), 485–492. https://doi.org/10.1097/00002030-199605000-00006

Reduction Of The In Vitro Activity Of A77003, An Inhibitor Of Human Immunodeficiency Virus Protease, By Human Serum  1 Acid Glycoprotein

Journal of Infectious Diseases / Mar 01, 1995

Bilello, J. A., Bilello, P. A., Prichard, M., Robins, T., & Drusano, G. L. (1995). Reduction Of The In Vitro Activity Of A77003, An Inhibitor Of Human Immunodeficiency Virus Protease, By Human Serum  1 Acid Glycoprotein. Journal of Infectious Diseases, 171(3), 546–551. https://doi.org/10.1093/infdis/171.3.546

In vitro pharmacodynamic modeling of anti-retroviral agents and interferon

Antiviral Research / Apr 01, 1991

Bilello, J. A., Dudley, M. N., & Drusano, G. L. (1991). In vitro pharmacodynamic modeling of anti-retroviral agents and interferon. Antiviral Research, 15, 151. https://doi.org/10.1016/0166-3542(91)90290-8

Lymphocyte transformation abnormalities in bovine immunodeficiency-like virus infected calves

Immunology Letters / Feb 01, 1991

Martin, S. J., O’Neill, T. P., Bilello, J. A., & Eiseman, J. L. (1991). Lymphocyte transformation abnormalities in bovine immunodeficiency-like virus infected calves. Immunology Letters, 27(2), 81–84. https://doi.org/10.1016/0165-2478(91)90132-t

Altered cellular functions in a PC-12 cell clone chronically infected with retrovirus

Biochemical and Biophysical Research Communications / Oct 01, 1986

Bilello, J. A., Hoffman, P. M., & Max, S. R. (1986). Altered cellular functions in a PC-12 cell clone chronically infected with retrovirus. Biochemical and Biophysical Research Communications, 140(2), 706–714. https://doi.org/10.1016/0006-291x(86)90789-8

Interferon-induced alterations in membrane functions and the growth of Daudi lymphoma and Friend leukemia cells

Bioscience Reports / Aug 01, 1982

Siegler, E., Schaefer, A., & Bilello, J. A. (1982). Interferon-induced alterations in membrane functions and the growth of Daudi lymphoma and Friend leukemia cells. Bioscience Reports, 2(8), 605–608. https://doi.org/10.1007/bf01314223

Biosynthesis, Modification and Processing of Viral Polyproteins

Protein Biosynthesis in Eukaryotes / Jan 01, 1982

Koch, G., Koch, F., Bilello, J. A., Hiller, E., Schârli, C., Warnecke, G., & Weber, C. (1982). Biosynthesis, Modification and Processing of Viral Polyproteins. In Protein Biosynthesis in Eukaryotes (pp. 275–309). Springer US. https://doi.org/10.1007/978-1-4684-4124-6_12

ALTERATIONS IN THE PROCESSING AND SHEDDING OF RETROVIRUS PROTEINS IN FRIEND ERYTHROLEUKEMIA CELLS

Biosynthesis, Modification, and Processing of Cellular and Viral Polyproteins / Jan 01, 1980

Bilello, J. A., Warnecke, G., Weber, C., & Koch, G. (1980). ALTERATIONS IN THE PROCESSING AND SHEDDING OF RETROVIRUS PROTEINS IN FRIEND ERYTHROLEUKEMIA CELLS. In Biosynthesis, Modification, and Processing of Cellular and Viral Polyproteins (pp. 185–201). Elsevier. https://doi.org/10.1016/b978-0-12-417560-0.50021-0

SFFV SPECIFIC GENE EXPRESSION IN INFECTED AND ERYTHROLEUKEMIA CELLS

Animal Virus Genetics / Jan 01, 1980

Frisby, D., Colletta, G., Pragnell, I., Ostertag, W., Bilello, J., Warnecke, G., & Koch, G. (1980). SFFV SPECIFIC GENE EXPRESSION IN INFECTED AND ERYTHROLEUKEMIA CELLS. In Animal Virus Genetics (pp. 411–423). Elsevier. https://doi.org/10.1016/b978-0-12-255850-4.50041-x

Growth of Murine Sarcoma Virus-Transformed Rat Kidney Cells in Nude Mice: Absence of Induction of Host Endogenous Viruses 2

JNCI: Journal of the National Cancer Institute / Jun 01, 1977

Bilello, J. A., Freedman, V. H., & Shin, S. (1977). Growth of Murine Sarcoma Virus-Transformed Rat Kidney Cells in Nude Mice: Absence of Induction of Host Endogenous Viruses 2. JNCI: Journal of the National Cancer Institute, 58(6), 1691–1694. https://doi.org/10.1093/jnci/58.6.1691

Patterns of chronic inflammation in extensively treated patients with arachnoiditis and chronic intractable pain

Postgraduate Medicine / Dec 17, 2016

Bilello, J. A., & Tennant, F. S. (2016). Patterns of chronic inflammation in extensively treated patients with arachnoiditis and chronic intractable pain. Postgraduate Medicine, 129(1), 87–91. https://doi.org/10.1080/00325481.2017.1270155

Seeking an objective diagnosis of depression

Biomarkers in Medicine / Aug 01, 2016

Bilello, J. A. (2016). Seeking an objective diagnosis of depression. Biomarkers in Medicine, 10(8), 861–875. https://doi.org/10.2217/bmm-2016-0076

A Phase 1B, randomized, double blind, placebo controlled, multiple-dose escalation study of NSI-189 phosphate, a neurogenic compound, in depressed patients

Molecular Psychiatry / Dec 08, 2015

Fava, M., Johe, K., Ereshefsky, L., Gertsik, L. G., English, B. A., Bilello, J. A., Thurmond, L. M., Johnstone, J., Dickerson, B. C., Makris, N., Hoeppner, B. B., Flynn, M., Mischoulon, D., Kinrys, G., & Freeman, M. P. (2015). A Phase 1B, randomized, double blind, placebo controlled, multiple-dose escalation study of NSI-189 phosphate, a neurogenic compound, in depressed patients. Molecular Psychiatry, 21(10), 1372–1380. https://doi.org/10.1038/mp.2015.178

Assessment of a multi-assay, serum-based biological diagnostic test for major depressive disorder: a Pilot and Replication Study

Molecular Psychiatry / Dec 13, 2011

Papakostas, G. I., Shelton, R. C., Kinrys, G., Henry, M. E., Bakow, B. R., Lipkin, S. H., Pi, B., Thurmond, L., & Bilello, J. A. (2011). Assessment of a multi-assay, serum-based biological diagnostic test for major depressive disorder: a Pilot and Replication Study. Molecular Psychiatry, 18(3), 332–339. https://doi.org/10.1038/mp.2011.166

Matrix metalloproteinases during and outside of migraine attacks without aura

Cephalalgia / Aug 01, 2009

Ashina, M., Tvedskov, J., Lipka, K., Bilello, J., Penkowa, M., & Olesen, J. (2009). Matrix metalloproteinases during and outside of migraine attacks without aura. Cephalalgia, 30(3), 303–310. https://doi.org/10.1111/j.1468-2982.2009.01954.x

Profiling serum biomarkers in patients with COPD: associations with clinical parameters

Thorax / Feb 27, 2007

Pinto-Plata, V., Toso, J., Lee, K., Park, D., Bilello, J., Mullerova, H., De Souza, M. M., Vessey, R., & Celli, B. (2007). Profiling serum biomarkers in patients with COPD: associations with clinical parameters. Thorax, 62(7), 595–601. https://doi.org/10.1136/thx.2006.064428

Use of Proteomic Patterns of Serum Biomarkers in Patients with Chronic Obstructive Pulmonary Disease: Correlation with Clinical Parameters

Proceedings of the American Thoracic Society / Aug 01, 2006

Pinto-Plata, V. (2006). Use of Proteomic Patterns of Serum Biomarkers in Patients with Chronic Obstructive Pulmonary Disease: Correlation with Clinical Parameters. Proceedings of the American Thoracic Society, 3(6), 465–466. https://doi.org/10.1513/pats.200603-030ms

The Agony and Ecstasy of “OMIC” Technologies in Drug Development

Current Molecular Medicine / Feb 01, 2005

Bilello, J. (2005). The Agony and Ecstasy of “OMIC” Technologies in Drug Development. Current Molecular Medicine, 5(1), 39–52. https://doi.org/10.2174/1566524053152898

In Vitro-In Vivo Model for Evaluating the Antiviral Activity of Amprenavir in Combination with Ritonavir Administered at 600 and 100 Milligrams, Respectively, Every 12 Hours

Antimicrobial Agents and Chemotherapy / Nov 01, 2003

Preston, S. L., Piliero, P. J., Bilello, J. A., Stein, D. S., Symonds, W. T., & Drusano, G. L. (2003). In Vitro-In Vivo Model for Evaluating the Antiviral Activity of Amprenavir in Combination with Ritonavir Administered at 600 and 100 Milligrams, Respectively, Every 12 Hours. Antimicrobial Agents and Chemotherapy, 47(11), 3393–3399. https://doi.org/10.1128/aac.47.11.3393-3399.2003

Pharmacodynamics of Abacavir in an In Vitro Hollow-Fiber Model System

Antimicrobial Agents and Chemotherapy / Feb 01, 2002

Drusano, G. L., Bilello, P. A., Symonds, W. T., Stein, D. S., McDowell, J., Bye, A., & Bilello, J. A. (2002). Pharmacodynamics of Abacavir in an In Vitro Hollow-Fiber Model System. Antimicrobial Agents and Chemotherapy, 46(2), 464–470. https://doi.org/10.1128/aac.46.2.464-470.2002

Hollow‐Fiber Unit Evaluation of a New Human Immunodeficiency Virus Type 1 Protease Inhibitor, BMS‐232632, for Determination of the Linked Pharmacodynamic Variable

The Journal of Infectious Diseases / Apr 01, 2001

Drusano, G. L., Bilello, J. A., Preston, S. L., O’Mara, E., Kaul, S., Schnittman, S., & Echols, R. (2001). Hollow‐Fiber Unit Evaluation of a New Human Immunodeficiency Virus Type 1 Protease Inhibitor, BMS‐232632, for Determination of the Linked Pharmacodynamic Variable. The Journal of Infectious Diseases, 183(7), 1126–1129. https://doi.org/10.1086/319281

Use of Drug Effect Interaction Modeling with Monte Carlo Simulation To Examine the Impact of Dosing Interval on the Projected Antiviral Activity of the Combination of Abacavir and Amprenavir

Antimicrobial Agents and Chemotherapy / Jun 01, 2000

Drusano, G. L., D’Argenio, D. Z., Preston, S. L., Barone, C., Symonds, W., LaFon, S., Rogers, M., Prince, W., Bye, A., & Bilello, J. A. (2000). Use of Drug Effect Interaction Modeling with Monte Carlo Simulation To Examine the Impact of Dosing Interval on the Projected Antiviral Activity of the Combination of Abacavir and Amprenavir. Antimicrobial Agents and Chemotherapy, 44(6), 1655–1659. https://doi.org/10.1128/aac.44.6.1655-1659.2000

The Safety and Efficacy of Granulocyte‐Macrophage Colony‐Stimulating Factor (Sargramostim) Added to Indinavir‐ or Ritonavir‐Based Antiretroviral Therapy: A Randomized Double‐Blind, Placebo‐Controlled Trial

The Journal of Infectious Diseases / Oct 01, 1999

Skowron, G., Stein, D., Drusano, G., Melbourne, K., Bilello, J., Mikolich, D., Rana, K., Agosti, J. M., Mongillo, A., Whitmore, J., & Gilbert, M. J. (1999). The Safety and Efficacy of Granulocyte‐Macrophage Colony‐Stimulating Factor (Sargramostim) Added to Indinavir‐ or Ritonavir‐Based Antiretroviral Therapy: A Randomized Double‐Blind, Placebo‐Controlled Trial. The Journal of Infectious Diseases, 180(4), 1064–1071. https://doi.org/10.1086/314981

Nucleoside Analog 1592U89 and Human Immunodeficiency Virus Protease Inhibitor 141W94 Are Synergistic In Vitro

Antimicrobial Agents and Chemotherapy / Sep 01, 1998

Drusano, G. L., D’Argenio, D. Z., Symonds, W., Bilello, P. A., McDowell, J., Sadler, B., Bye, A., & Bilello, J. A. (1998). Nucleoside Analog 1592U89 and Human Immunodeficiency Virus Protease Inhibitor 141W94 Are Synergistic In Vitro. Antimicrobial Agents and Chemotherapy, 42(9), 2153–2159. https://doi.org/10.1128/aac.42.9.2153

Phenotypic Variability of Lymphocyte Populations in Peripheral Blood and Lymph Nodes from HIV-Infected Individuals and the Impact of Antiretroviral Therapy

AIDS Research and Human Retroviruses / Mar 20, 1998

LANDAY, A. L., BETHEL, J., & SCHNITTMAN, S. (1998). Phenotypic Variability of Lymphocyte Populations in Peripheral Blood and Lymph Nodes from HIV-Infected Individuals and the Impact of Antiretroviral Therapy. AIDS Research and Human Retroviruses, 14(5), 445–451. https://doi.org/10.1089/aid.1998.14.445

Factors Influencing the Emergence of Resistance to Indinavir: Role of Virologic, Immunologic, and Pharmacologic Variables

Journal of Infectious Diseases / Aug 01, 1998

Drusano, G. L., Bilello, J. A., Stein, D. S., Nessly, M., Meibohm, A., Emini, E. A., Deutsch, P., Condra, J., Chodakewitz, J., & Holder, D. J. (1998). Factors Influencing the Emergence of Resistance to Indinavir: Role of Virologic, Immunologic, and Pharmacologic Variables. Journal of Infectious Diseases, 178(2), 360–367. https://doi.org/10.1086/515631

Predicting Clinical Progression or Death in Subjects with Early‐Stage Human Immunodeficiency Virus (HIV) Infection: A Comparative Analysis of Quantification of HIV RNA, Soluble Tumor Necrosis Factor Type II Receptors, Neopterin, and $\beta _{2}$ -Microglobulin

The Journal of Infectious Diseases / Nov 01, 1997

Stein, D. S., Lyles, R. H., Graham, N. M. H., Tassoni, C. J., Margolick, J. B., Phair, J. P., Rinaldo, C., Saah, R. D. A., & Bilello, J. (1997). Predicting Clinical Progression or Death in Subjects with Early‐Stage Human Immunodeficiency Virus (HIV) Infection: A Comparative Analysis of Quantification of HIV RNA, Soluble Tumor Necrosis Factor Type II Receptors, Neopterin, and $\beta _{2}$ -Microglobulin. The Journal of Infectious Diseases, 176(5), 1161–1167. https://doi.org/10.1086/514108

Soluble Tumor Necrosis Factor-  Receptor Type II (sTNF RII) Correlates with Human Immunodeficiency Virus (HIV) RNA Copy Number in HIV-Infected Patients

Journal of Infectious Diseases / Feb 01, 1996

Bilello, J. A., Stellrecht, K., Drusano, G. L., & Stein, D. S. (1996). Soluble Tumor Necrosis Factor-  Receptor Type II (sTNF RII) Correlates with Human Immunodeficiency Virus (HIV) RNA Copy Number in HIV-Infected Patients. Journal of Infectious Diseases, 173(2), 464–467. https://doi.org/10.1093/infdis/173.2.464

Antiretroviral Monotherapy in Early Stage Human Immunodeficiency Virus Disease Has No Detectable Effect on Virus Load in Peripheral Blood and Lymph Nodes

Journal of Infectious Diseases / Apr 01, 1996

Cohen, O. J., Pantaleo, G., Holodniy, M., Fox, C. H., Orenstein, J. M., Schnittman, S., Niu, M., Graziosi, C., Pavlakis, G. N., Lalezari, J., Bartlett, J. A., Steigbigel, R. T., Cohn, J., Novak, R., McMahon, D., Bilello, J., & Fauci, A. S. (1996). Antiretroviral Monotherapy in Early Stage Human Immunodeficiency Virus Disease Has No Detectable Effect on Virus Load in Peripheral Blood and Lymph Nodes. Journal of Infectious Diseases, 173(4), 849–856. https://doi.org/10.1093/infdis/173.4.849

Modeling combinations of antiretroviral agents in vitro with integration of pharmacokinetics: guidance in regimen choice for clinical trial evaluation

Antimicrobial Agents and Chemotherapy / May 01, 1996

Drusano, G. L., Prichard, M., Bilello, P. A., & Bilello, J. A. (1996). Modeling combinations of antiretroviral agents in vitro with integration of pharmacokinetics: guidance in regimen choice for clinical trial evaluation. Antimicrobial Agents and Chemotherapy, 40(5), 1143–1147. https://doi.org/10.1128/aac.40.5.1143

Relevance of Plasma Protein Binding to Antiviral Activity and Clinical Efficacy of Inhibitors of Human Immunodeficiency Virus Protease

Journal of Infectious Diseases / Jun 01, 1996

Bilello, J. A., & Drusano, G. L. (1996). Relevance of Plasma Protein Binding to Antiviral Activity and Clinical Efficacy of Inhibitors of Human Immunodeficiency Virus Protease. Journal of Infectious Diseases, 173(6), 1524–1525. https://doi.org/10.1093/infdis/173.6.1524

Human serum alpha 1 acid glycoprotein reduces uptake, intracellular concentration, and antiviral activity of A-80987, an inhibitor of the human immunodeficiency virus type 1 protease

Antimicrobial Agents and Chemotherapy / Jun 01, 1996

Bilello, J. A., Bilello, P. A., Stellrecht, K., Leonard, J., Norbeck, D. W., Kempf, D. J., Robins, T., & Drusano, G. L. (1996). Human serum alpha 1 acid glycoprotein reduces uptake, intracellular concentration, and antiviral activity of A-80987, an inhibitor of the human immunodeficiency virus type 1 protease. Antimicrobial Agents and Chemotherapy, 40(6), 1491–1497. https://doi.org/10.1128/aac.40.6.1491

Transmission in NFS/N mice of the heritable spongiform encephalopathy associated with the gray tremor mutation.

Proceedings of the National Academy of Sciences / Jun 01, 1987

Hoffman, P. M., Rohwer, R. G., MacAuley, C., Bilello, J. A., Hartley, J. W., & Morse, H. C. (1987). Transmission in NFS/N mice of the heritable spongiform encephalopathy associated with the gray tremor mutation. Proceedings of the National Academy of Sciences, 84(11), 3866–3870. https://doi.org/10.1073/pnas.84.11.3866

Murine Sarcoma Virus Gene Expression: Transformants Which Express Viral Envelope Glycoprotein In The Absence Of The Major Internal Protein And Infectious Particles

Proceedings of the National Academy of Sciences / Aug 01, 1974

Bilello, J. A., Strand, M., & August, J. T. (1974). Murine Sarcoma Virus Gene Expression: Transformants Which Express Viral Envelope Glycoprotein In The Absence Of The Major Internal Protein And Infectious Particles. Proceedings of the National Academy of Sciences, 71(8), 3234–3238. https://doi.org/10.1073/pnas.71.8.3234

Education

Albert Einstein College of Medicine

Ph.D/Molecular Biology, Molecular Biology / June, 1977

New York

Southern Illinois University Carbondale

MA/Microbiology, Microbiology / June, 1969

Carbondale, Illinois, United States of America

City College of New York

BS, Biology / January, 1966

New York, New York, United States of America

Albert Einstein College of Medicine

Ph.D/Molecular Biology, Molecular Biology / June, 1977

New York

Southern Illinois University Carbondale

MA/Microbiology, Microbiology / June, 1969

Carbondale, Illinois, United States of America

City College of New York

BS, Biology / January, 1966

New York, New York, United States of America

Experience

Innovalyst ICAN

Principal / July, 2018Present

Principal / July, 2018Present

Atlantic Diagnostic Laboratory

Scientific Officer / January, 2017Present

Scientific Officer / January, 2017Present

Ridge Diagnostic Laboratories

President and Chief Scientific Officer / January, 2009December, 2016

President and Chief Scientific Officer / January, 2009December, 2016

Ridge Diagnostics

Founder/Chief Scientific Officer / January, 2006December, 2008

Founder/Chief Scientific Officer / January, 2006December, 2008

GlaxoSmithKline

Director Technology Development / October, 2002December, 2005

Senior Therapeutic Area Advisor for Antivirals / January, 2002October, 2002

Director Technology Development / October, 2002December, 2005

Senior Therapeutic Area Advisor for Antivirals / January, 2002October, 2002

Virco Lab

Director, Preclinical Research and Development / June, 2000June, 2002

Director, Preclinical Research and Development / June, 2000June, 2002

SRA Life Sciences

19982000

19982000

Albany Medical College

Associate Professor of Medicine / 19921998

Associate Professor of Medicine / 19921998

Baltimore VA Medical Center

Chief, Molecular Biology Laboratory / 19851992

Chief, Molecular Biology Laboratory / 19851992

University of Maryland Baltimore

Assistant Professor / 19831989

Assistant Professor / 19831989

Johns Hopkins Medicine

Instructor / 19811983

Instructor / 19811983

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