Peyman Ghorbani

Immunologist with metabolism and infection experience in macrophages, dendritic cells, and T cells

Research Expertise

Immunology
Metabolism
Infection

Publications

Selective and efficient generation of functional Batf3-dependent CD103+ dendritic cells from mouse bone marrow
Blood
2014
Short-chain fatty acids affect cystic fibrosis airway inflammation and bacterial growth
European Respiratory Journal
2015
Choline transport links macrophage phospholipid metabolism and inflammation
Journal of Biological Chemistry
2018
Interleukin-18 up-regulates amino acid transporters and facilitates amino acid–induced mTORC1 activation in natural killer cells
Journal of Biological Chemistry
2019
Few Foxp3+ regulatory T cells are sufficient to protect adult mice from lethal autoimmunity
European Journal of Immunology
2014
De Novo Fatty Acid Synthesis During Mycobacterial Infection Is a Prerequisite for the Function of Highly Proliferative T Cells, But Not for Dendritic Cells or Macrophages
Frontiers in Immunology
2018
Rapid Rebound of the Treg Compartment in DEREG Mice Limits the Impact of Treg Depletion on Mycobacterial Burden, but Prevents Autoimmunity
PLoS ONE
2014
Effect of Arginase Inhibition on Pulmonary L-Arginine Metabolism in Murine Pseudomonas Pneumonia
PLoS ONE
2014
Anti Diabetic effect of CL 316,243 (A β3-Adrenergic Agonist) by Down Regulation of Tumour Necrosis Factor (TNF-α) Expression
PLoS ONE
2012
Metabolites: deciphering the molecular language between DCs and their environment
Seminars in Immunopathology
2016
Adoptive transfer of splenocytes to study cell-mediated immune responses in hepatitis C infection using HCV transgenic mice
Comparative Hepatology
2010
Characterization of Redox-Responsive LXR-Activating Nanoparticle Formulations in Primary Mouse Macrophages
Molecules
2019
In Vitro Hepatitis C Virus Infection and Hepatic Choline Metabolism
Viruses
2020
Myeloid deletion and therapeutic activation of AMPK do not alter atherosclerosis in male or female mice
Journal of Lipid Research
2020
Hepatic Choline Transport Is Inhibited During Fatty Acid–Induced Lipotoxicity and Obesity
Hepatology Communications
2020
Does prenylation predict progression in NAFLD?
The Journal of Pathology
2018
Thermoneutral housing does not accelerate metabolic dysfunction-associated fatty liver disease in male or female C57Bl/6J mice fed a Western diet
American Journal of Physiology-Endocrinology and Metabolism
2023
The aryl hydrocarbon receptor in β-cells mediates the effects of TCDD on glucose homeostasis in mice
Molecular Metabolism
2024
Myeloid deletion and therapeutic activation of AMP-activated protein kinase (AMPK) do not alter atherosclerosis in male or female mice
Unknown Venue
2020
Choline metabolism underpins macrophage IL-4 polarization and RELMα up-regulation in helminth infection
PLOS Pathogens
2023
Pancreas-derived DPP4 is not essential for glucose homeostasis under metabolic stress
iScience
2023
Regulation of DC metabolism by nitric oxide in murine GM‐CSF cultures
European Journal of Immunology
2022
Thermoneutral housing does not accelerate metabolic dysfunction-associated fatty liver disease in male or female mice fed a Western diet
Unknown Venue
2023
Choline metabolism promotes M2 macrophage polarization in intestinal infection with helminth Heligmosomoides polygyrus
The Journal of Immunology
2022
Choline metabolism underpins macrophage IL-4 polarization in vitro and in vivo
The Journal of Immunology
2022
Characterization of LXR-activating nanoparticle formulations in primary mouse macrophages
Unknown Venue
2019
Fatty acid-induced lipotoxicity inhibits choline metabolism independent of ER stress in mouse primary hepatocytes
Unknown Venue
2019
Dendritic Cells in Listeria monocytogenes Infection
Immunity to Listeria Monocytogenes
2012
Modulation of inflammatory and immune responses by short-chain fatty acids
Diet, Immunity and Inflammation
2013
Effects Of Systemic Arginase Inhibition On Nitric Oxide Production In A Mouse Model Of Pseudomonas Pneumonia
C108. PEDIATRIC CYSTIC FIBROSIS AND PRIMARY CILIARY DYSKINESIA
2012
Choline metabolism underpins macrophage IL-4 polarization and RELMα up-regulation in helminth infection
Unknown Venue
2022

Education

Medizinische Hochschule Hannover

Ph.D., Infection Biology/Immunology / June, 2016

Hanover

University of Toronto

M.Sc., Laboratory Medicine & Pathobiology / October, 2012

Toronto, Ontario, Canada

Experience

University of Ottawa

Postdoctoral Fellow / September, 2017Present

VBI Vaccines

Research Assistant / June, 2007August, 2009

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