Massimo Nardone

University of Guelph

Research Expertise

Sympathetic Nervous System
Blood Pressure Regulation
Cardiovascular physiology
Physiology
Endocrinology, Diabetes and Metabolism
Endocrine and Autonomic Systems

Legacy Map

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Publications

Evidence for Pressure‐Independent Sympathetic Modulation of Central Pulse Wave Velocity
Journal of the American Heart Association
2018
Sympathetic neural modulation of arterial stiffness in humans
American Journal of Physiology-Heart and Circulatory Physiology
2020
Muscle sympathetic nerve responses to passive and active one-legged cycling: insights into the contributions of central command
American Journal of Physiology-Heart and Circulatory Physiology
2018
Sex Differences in Muscle Metaboreflex Activation after Static Handgrip Exercise
Medicine & Science in Sports & Exercise
2021
Noninvasive Microvascular Indices Reveal Peripheral Vascular Abnormalities in Patients With Suspected Coronary Microvascular Dysfunction
Canadian Journal of Cardiology
2020
Effects of muscle sympathetic burst size and burst pattern on time-to-peak sympathetic transduction
Applied Physiology, Nutrition, and Metabolism
2021
Signal-averaged resting sympathetic transduction of blood pressure: is it time to account for prevailing muscle sympathetic burst frequency?
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
2021
Within-breath sympathetic baroreflex sensitivity is modulated by lung volume but unaffected by acute intermittent hypercapnic hypoxia in men
American Journal of Physiology-Heart and Circulatory Physiology
2020
Blood pressure oscillations impact signal-averaged sympathetic transduction of blood pressure: implications for the association with resting sympathetic outflow
American Journal of Physiology-Heart and Circulatory Physiology
2021
Muscle Metaboreflex Control of Sympathetic Activity Is Preserved after Acute Intermittent Hypercapnic Hypoxia
Medicine & Science in Sports & Exercise
2021
Assessing functional sympatholysis during rhythmic handgrip exercise using Doppler ultrasound and near-infrared spectroscopy: sex differences and test-retest reliability
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
2022
Reply to Fadel et al.
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
2022
Muscle sympathetic single-unit responses during rhythmic handgrip exercise and isocapnic hypoxia in males: the role of sympathoexcitation magnitude
Journal of Neurophysiology
2021
Characterization of the Human Coronary Microvascular Response to Multiple Hyperaemic Agents
CJC Open
2021
Standard exercise stress testing attenuates peripheral microvascular function in patients with suspected coronary microvascular dysfunction
BMC Sports Science, Medicine and Rehabilitation
2021
Effect of a neck compression collar on cardiorespiratory and cerebrovascular function in postural orthostatic tachycardia syndrome (POTS)
Journal of Applied Physiology
2020
Attenuated Sympathetic Blood Pressure Transduction in Patients With Treated Heart Failure With Reduced Ejection Fraction
Hypertension
2022
Action potential amplitude and baroreflex resetting of action potential clusters mediate hypoxia‐induced sympathetic long‐term facilitation
The Journal of Physiology
2022
Higher sympathetic transduction is independently associated with greater very short-term diastolic blood pressure variability in young healthy males and females
Clinical Autonomic Research
2023
Potentiation of GABAergic synaptic transmission by diazepam acutely increases resting beat-to-beat blood pressure variability in young adults
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
2022
Renal vascular conductance is unrelated to leg vascular conductance or muscle sympathetic nerve activity at rest and during stress in humans
Journal of Applied Physiology
2023
CKD patients have augmented beat-to-beat BP variability that is not improved with 12 weeks of cycling exercise
Physiology
2023
Augmented sympathetic neurovascular transduction following acute exercise in normotensive adults
Physiology
2023
Cardiorespiratory coupling of sympathetic outflow in humans: a comparison of respiratory and cardiac modulation of sympathetic nerve activity to skin and muscle
Experimental Physiology
2013
Cannabis Inhalation Acutely Reduces Muscle Sympathetic Nerve Activity in Humans
Circulation
2022
Abstract 13228: Cannabis Inhalation Reduces Muscle Sympathetic Nerve Activity in Humans
Circulation
2022
Pressor Response To Blood-Flow Restriction Exercise: Influence Of Muscle Mass And Central Blood Volume Reduction
Medicine & Science in Sports & Exercise
2022
Hypoxia‐induced sympathetic long‐term facilitation is mediated by a rightward shift in sympathetic action potential amplitude distribution and baroreflex resetting of action potential clusters
The FASEB Journal
2022
Intra and inter‐day reproducibility of the functional sympatholysis protocol during rhythmic handgrip exercise in healthy humans
The FASEB Journal
2022
Sympathetic transduction of blood pressure during graded lower body negative pressure
The FASEB Journal
2022
Autonomic and neuroendocrine modulation of arterial stiffness and hemodynamics
Textbook of Arterial Stiffness and Pulsatile Hemodynamics in Health and Disease
2022
Muscle sympathetic single-unit response patterns during progressive muscle metaboreflex activation in young healthy adults
Journal of Neurophysiology
2020
Case Studies in Physiology: Sympathetic neural discharge patterns in a healthy young male during end-expiratory breath hold-induced sinus pause
Journal of Applied Physiology
2020
Stretching our understanding of baroreflex control in humans: evidence of a positive feedback pulmonary baroreflex
The Journal of Physiology
2020
Comparison of Non‐Invasive Peripheral Vascular Function to Invasive Measures of Coronary Function in Patients with Suspected Coronary Microvascular Dysfunction
The FASEB Journal
2019
Validity and reliability of measuring resting muscle sympathetic nerve activity using short sampling durations in healthy humans
Journal of Applied Physiology
2016

Education

York University

MSc, Physiology / 2019

Toronto, Ontario, Canada

University of Guelph

Ph.D, Physiology / 2023 (anticipated)

Guelph, Ontario, Canada
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