Lindsay Webb, PhD

Immunologist and cancer biologist passionate about driving innovative research to improve patient health

Research Expertise

Cancer Research
Immunology and Allergy
Molecular Medicine
Pharmacology
Oncology
Immunology
Molecular Biology

About

Immunologist with expertise in T cell biology and molecular mechanisms of inflammation and anti-tumor immunity. Expert in drug development of biologics and cell therapies from early discovery to IND-enabling studies for oncology and autoimmune indications.

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Publications

203 A membrane-tethered IL-15/IL-15 receptor fusion protein enhances the persistence and efficacy of CD70-targeted TRuC-T cells
Journal for ImmunoTherapy of Cancer
2021
173 Expression of a membrane-tethered IL-15/IL-15 receptor fusion protein enhances the persistence of MSLN-targeted TRuC-T cells
Journal for ImmunoTherapy of Cancer
2021
M9657 Is a Bispecific Tumor-Targeted Anti-CD137 Agonist That Induces MSLN-Dependent Antitumor Immunity without Liver Inflammation
Cancer Immunology Research
2023
Abstract P077: Composition of CD4 T cell subsets and impact on tumor growth control across mouse syngeneic tumor models
Cancer Immunology Research
2022
757 M9657, a novel tumor-targeted conditional anti-CD137 agonist displays MSLN-dependent anti-tumor immunity
Journal for ImmunoTherapy of Cancer
2021
Protein arginine methyltransferase 5 promotes cholesterol biosynthesis–mediated Th17 responses and autoimmunity
Journal of Clinical Investigation
2020
NF-κB/mTOR/MYC Axis Drives PRMT5 Protein Induction After T Cell Activation via Transcriptional and Non-transcriptional Mechanisms
Frontiers in Immunology
2019
Emerging Role for Methylation in Multiple Sclerosis: Beyond DNA
Trends in Molecular Medicine
2017
PRMT5-Selective Inhibitors Suppress Inflammatory T Cell Responses and Experimental Autoimmune Encephalomyelitis
The Journal of Immunology
2017
Helminth-induced Ly6Chi monocyte-derived alternatively activated macrophages suppress experimental autoimmune encephalomyelitis
Scientific Reports
2017
Novel Markers to Delineate Murine M1 and M2 Macrophages
PLOS ONE
2015

Education

University of Cincinnati

BS, Cell and Molecular Biology / May, 2014

Cincinnati, Ohio, United States of America

The Ohio State University

Ph.D., Biomedical Sciences/ Immunology / December, 2018

Columbus, Ohio, United States of America

Experience

Dynamic Cell Therapies

Principal Scientist / May, 2023Present

TCR2 Therapeutics

Senior Scientist / May, 2021May, 2023

EMD Serono

Scientist / June, 2019May, 2021

Links & Social Media

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