Tshering Lama-Sherpa

Postdoctoral Fellow at UT Southwestern Medical Center with over 10 years of experience in cancer research.

Research Expertise

Cancer Biology
Molecular Biology
Cellular Signaling
Oncology
Cancer Research
Pathology and Forensic Medicine
Ecology, Evolution, Behavior and Systematics
Genetics
Genetics (clinical)
Biochemistry
Structural Biology
Hematology
Immunology
Cell Biology
Immunology and Allergy
Animal Science and Zoology
Plant Science
Agronomy and Crop Science
Horticulture
Food Science
Soil Science

About

I am passionate about developing novel molecular and genetic strategies for the treatment of cancer, metabolic disorders, and diabetes. I am motivated by the potential impact of my research on improving the lives of patients and advancing the scientific knowledge in the field. I enjoy collaborating with other researchers, sharing ideas, and learning new skills.

Legacy Map

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Publications

Adipocyte-Lineage Cells Support Growth and Dissemination of Multiple Myeloma in Bone
The American Journal of Pathology
2016
Hedgehog Signaling Regulates Metabolism and Polarization of Mammary Tumor-Associated Macrophages
Cancer Research
2021
An Emerging Regulatory Role for the Tumor Microenvironment in the DNA Damage Response to Double-Strand Breaks
Molecular Cancer Research
2020
AKAP13 couples GPCR signaling to mTORC1 inhibition
PLOS Genetics
2021
Normalizing glucose levels reconfigures the mammary tumor immune and metabolic microenvironment and decreases metastatic seeding
Cancer Letters
2021
Regulation of mTORC1 by the Rag GTPases
Biochemical Society Transactions
2023
SNAT7 regulates mTORC1 via macropinocytosis
Proceedings of the National Academy of Sciences
2022
Hedgehog signaling enables repair of ribosomal DNA double-strand breaks
Nucleic Acids Research
2020
Quantitative Longitudinal Imaging Reveals that Inhibiting Hedgehog Activity Alleviates the Hypoxic Tumor Landscape
Molecular Cancer Research
2021
Curcumin/cellulose micro crystals/chitosan films: Water absorption behavior and in vitro cytotoxicity
International Journal of Biological Macromolecules
2015
Abstract 115: Hedgehog signaling pathway promotes breast cancer adaptation to hypoxia
Cancer Research
2020
Hedgehog Signaling in Carcinogenesis
Predictive Biomarkers in Oncology
2018
The Role of Adipocyte Lineage Cells in Myeloma Growth and Dissemination in Bone
Blood
2015
Abstract 2103: Hedgehog signaling regulates metabolism and polarization of mammary tumor-associated macrophages
Cancer Research
2022
Hedgehog signaling induced metabolic reprogramming is essential for M2 polarization of macrophages in breast cancer
The Journal of Immunology
2020
Abstract P3-01-25: Hedgehog signaling-mediated adaptation to hypoxic microenvironment promotes osteoclastogenesis in advanced breast cancer
Cancer Research
2020
Abstract 3740: Ionizing radiation-induced transcriptomic changes in triple-negative breast cancer cells reveal putative mechanisms of treatment resistance
Cancer Research
2019
1H NMR spectral analysis as a new aspect to evaluate the stability of some edible oils
Annals of Agricultural Sciences
2014
Reversible Modulation of Myofibroblast Differentiation in Adipose-Derived Mesenchymal Stem Cells
PLoS ONE
2014
Ubiquitin-Dependent Protein Degradation
Reference Module in Chemistry, Molecular Sciences and Chemical Engineering
2013
Amyloid Formation and Polymerization-dependent Inactivation of the Yeast Prion Protein, Ure2p
GBM Annual Spring meeting Mosbach 2005
2005

Education

Mississippi University for Women

Bachelor of Science in Biology, Science and Mathematics / May, 2014

Columbus, Mississippi, United States of America

University of Alabama at Birmingham

Ph.D., Molecular biology, Genetics, Biochemistry, Cancer Biology / December, 2020

Birmingham, Alabama, United States of America

Mississippi University for Women

Bachelor of Science in Biology, Science and Mathematics / May, 2014

Columbus, Mississippi, United States of America

Experience

University of Texas Southwestern Medical Center

Postdoctoral Researcher / February, 2021Present

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