Connor Duffy

Stanford Genetics Ph.D. candidate.; MIT Computer Science and Molecular Biology '17

San Francisco, California, United States of America

Research Expertise

genetics

neuroscience

computation

Oncology

Cancer Research

Biotechnology

Biochemistry

Biomaterials

Biomedical Engineering

Molecular Biology

Cell Biology

Pathology and Forensic Medicine

Histology

About

Connor Duffy is a 5th year PhD student in Genetics at Stanford, where he is using CRISPR screens in stem cell-derived brain organoids to study the genetic architecture of Alzheimer's disease risk. Connor graduated from MIT with a degree in Computer Science and Molecular Biology, where he played piano in the Chamber Music Society, served as president of the Debate Team, and created Science Olympiad at MIT, an organization that runs science tournaments for high school students. After college and before starting his PhD, he co-founded Reverie Labs, a machine learning-driven biotech company backed by Y Combinator, and was also a Data Insights Engineer at Flatiron Health.

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Publications

ecDNA hubs drive cooperative intermolecular oncogene expression

Nature

2021

Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence

Cancer Cell

2022

Covalently-crosslinked mucin biopolymer hydrogels for sustained drug delivery

Acta Biomaterialia

2015

Genome-wide, bidirectional CRISPR screens identify mucins as critical host factors modulating SARS-CoV-2 infection

Unknown Venue

2021

Tabula Microcebus: A transcriptomic cell atlas of mouse lemur, an emerging primate model organism

Unknown Venue

2021

Deep learning and CRISPR-Cas13d ortholog discovery for optimized RNA targeting

Cell Systems

2023

Adversarial domain translation networks for fast and accurate integration of large-scale atlas-level single-cell datasets

Unknown Venue

2021

An organism-wide atlas of hormonal signaling based on the mouse lemur single-cell transcriptome

Unknown Venue

2021

Mouse lemur transcriptomic atlas elucidates primate genes, physiology, disease, and evolution

Unknown Venue

2022

Education

Stanford University

Ph.D., Genetics / January, 2025 (anticipated)

Stanford, California, United States of America

Massachusetts Institute of Technology

S.B., Computer Science and Molecular Biology / February, 2017

Cambridge, Massachusetts, United States of America

Experience

Flatiron Health

Data Insights Engineer / October, 2018 — October, 2019

oncology data and software

Reverie Labs

Co-Founder / September, 2017 — September, 2018

computation-driven drug discovery; acq. Ginkgo Bioworks (NYSE: DNA)

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