Dr. Sagar Varankar, PhD

Experienced Stem Cell Biologist

Cambridge

Research Expertise

Stem Cell Biology
Cancer Biology

Education

National Centre for Cell Science

PhD in Cancer Biology / 2019

Master of Science, Biotechnology / June, 2011

Pune

University of Mumbai

Bachelor of Science, Biotechnology / June, 2009

Mumbai

Experience

Shift Bioscience Ltd.

Senior Scientist Target Validation / March, 2025Present

Setup research programs to rejuvenate various human cell types and validated targets identified from in silico analysis. Submitted safety and regulatory documents to the University of Cambridge Biosafety committee to undertake GM mouse work

Uncommon Bio Ltd.

Team Lead Advanced Cell Systems / July, 2022January, 2025

Spearheaded an iPSC organoid program to enable cross-functional collaboration and ensure seamless transition of RD pipelines to bench scale bioreactors. Engineered stem cell models optimized for high-density suspension growth and directed differentiation. Designed and implemented a quality pipeline ensuring full traceability of materials to support regulatory submissions for Novel Foods to the UK-FSA and US-FDA Led a core team of 4 scientists and matrix-managed an extended team of 5. Project managed business critical workflows with a risk management matrix to drive successful outcomes.

Wellcome-MRC Cambridge Stem Cell Institute

Post-Doctoral Research in Lung Regeneration / December, 2019June, 2022

Developed multi-cellular organoid models for idiopathic pulmonary fibrosis. Screened prophylactic drugs for SARS-CoV2 in human respiratory organoid cultures. Established an explant model to successfully transplant alveolar stem cells ex vivo. Undertook lineage tracing studies to decipher the impact of stromal signals on alveolar stem cell dynamics.

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