Dr. Sagar Varankar, PhD
Experienced Stem Cell Biologist
Research Expertise
About
Publications
Education
National Centre for Cell Science
PhD in Cancer Biology / 2019
Master of Science, Biotechnology / June, 2011
University of Mumbai
Bachelor of Science, Biotechnology / June, 2009
Experience
Shift Bioscience Ltd.
Senior Scientist Target Validation / March, 2025 — Present
Setup research programs to rejuvenate various human cell types and validated targets identified from in silico analysis. Submitted safety and regulatory documents to the University of Cambridge Biosafety committee to undertake GM mouse work
Uncommon Bio Ltd.
Team Lead Advanced Cell Systems / July, 2022 — January, 2025
Spearheaded an iPSC organoid program to enable cross-functional collaboration and ensure seamless transition of RD pipelines to bench scale bioreactors. Engineered stem cell models optimized for high-density suspension growth and directed differentiation. Designed and implemented a quality pipeline ensuring full traceability of materials to support regulatory submissions for Novel Foods to the UK-FSA and US-FDA Led a core team of 4 scientists and matrix-managed an extended team of 5. Project managed business critical workflows with a risk management matrix to drive successful outcomes.
Wellcome-MRC Cambridge Stem Cell Institute
Post-Doctoral Research in Lung Regeneration / December, 2019 — June, 2022
Developed multi-cellular organoid models for idiopathic pulmonary fibrosis. Screened prophylactic drugs for SARS-CoV2 in human respiratory organoid cultures. Established an explant model to successfully transplant alveolar stem cells ex vivo. Undertook lineage tracing studies to decipher the impact of stromal signals on alveolar stem cell dynamics.
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