Ian Hsu

PhD Candidate in Genome Engineering Hematopoietic Stem Cells

Research Expertise

Cell Biology
Hematology
Cancer Research
Molecular Biology
Genetics
Biomedical Engineering
Biotechnology
Molecular Medicine
Bioengineering
Applied Microbiology and Biotechnology

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Publications

Cas9-AAV6 gene correction of beta-globin in autologous HSCs improves sickle cell disease erythropoiesis in mice
Nature Communications
2021
Immunological barriers to haematopoietic stem cell gene therapy
Nature Reviews Immunology
2022
Use of polyvinyl alcohol for chimeric antigen receptor T-cell expansion
Experimental Hematology
2019
In Vitro Human Haematopoietic Stem Cell Expansion and Differentiation
Cells
2023
Multiplexed Assembly and Annotation of Synthetic Biology Constructs Using Long-Read Nanopore Sequencing
ACS Synthetic Biology
2022
Physioxia improves the selectivity of hematopoietic stem cell expansion cultures
Blood Advances
2023
Streamlined and quantitative detection of chimerism using digital PCR
Scientific Reports
2022
Circuit-seq: Circular reconstruction of cut in vitro transposed plasmids using Nanopore sequencing
Unknown Venue
2022
Large-scale in vivo CRISPR screens identify SAGA complex members as a key regulators of HSC lineage commitment and aging
Unknown Venue
2022
2014 – LARGE-SCALE IN VIVO CRISPR SCREENS IDENTIFY SAGA COMPLEX MEMBERS AS KEY REGULATORS OF HAEMATOPOIESIS
Experimental Hematology
2023
3103 – DEVELOPMENT OF EX VIVO HEMATOPOIETIC STEM CELL ASSAYS USING A HIGHLY SELECTIVE EXPANSION SYSTEM
Experimental Hematology
2022
3017 – ESTABLISHMENT OF A PLATFORM FOR EX VIVO GENE EDITING IN MULTIPOTENT HEMATOPOIETIC STEM CELLS
Experimental Hematology
2021
3042 – CAS9-AAV6 GENE CORRECTION OF AUTOLOGOUS HSCS IMPROVES SICKLE CELL DISEASE ERYTHROPOIESIS IN MICE
Experimental Hematology
2020
Genome engineering with Cas9 and AAV repair templates generates frequent concatemeric insertions of viral vectors
Nature Biotechnology
2024

Education

University of Oxford

Ph.D. Medical Sciences, Weatherall Institute for Molecular Medicine

Oxford

Dartmouth College

B.A. Biology | Minor: Economics / June, 2022

Hanover

Experience

University of Oxford

Wilkinson Lab / 2021Present

Dartmouth–Hitchcock Medical Center

McKenna Lab / 2020Present

Stanford University School of Medicine

Nakauchi Lab / 20172021

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