Cheshta Sharma

Research Scientist , University of Texas Health Science Center, San Antonio

Research Expertise

Mycology
Molecular biology
Fungal pathogenesis

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Publications

Candida auris: A rapidly emerging cause of hospital-acquired multidrug-resistant fungal infections globally
PLOS Pathogens
2017
Multidrug-Resistant Candida auris Misidentified as Candida haemulonii: Characterization by Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry and DNA Sequencing and Its Antifungal Susceptibility Profile Variability by Vitek 2, CLSI Broth Microdilution, and Etest Method
Journal of Clinical Microbiology
2015
A multicentre study of antifungal susceptibility patterns among 350 Candida auris isolates (2009–17) in India: role of the ERG11 and FKS1 genes in azole and echinocandin resistance
Journal of Antimicrobial Chemotherapy
2018
New Clonal Strain ofCandida auris, Delhi, India
Emerging Infectious Diseases
2013
Multidrug-resistant endemic clonal strain of Candida auris in India
European Journal of Clinical Microbiology & Infectious Diseases
2013
Comparison of EUCAST and CLSI Reference Microdilution MICs of Eight Antifungal Compounds for Candida auris and Associated Tentative Epidemiological Cutoff Values
Antimicrobial Agents and Chemotherapy
2017
Azole-Resistant Aspergillosis: Epidemiology, Molecular Mechanisms, and Treatment
The Journal of Infectious Diseases
2017
Clonal Expansion and Emergence of Environmental Multiple-Triazole-Resistant Aspergillus fumigatus Strains Carrying the TR34/L98H Mutations in the cyp51A Gene in India
PLoS ONE
2012
Invasive Mycosis Due to Species of Blastobotrys in Immunocompromised Patients with Reduced Susceptibility to Antifungals
Journal of Clinical Microbiology
2014
Post-transcriptional control of antifungal resistance in human fungal pathogens
Critical Reviews in Microbiology
2022
High terbinafine resistance in Trichophyton interdigitale isolates in Delhi, India harbouring mutations in the squalene epoxidase gene
Mycoses
2018
Identification by Molecular Methods and Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry and Antifungal Susceptibility Profiles of Clinically Significant Rare Aspergillus Species in a Referral Chest Hospital in Delhi, India
Journal of Clinical Microbiology
2016
Perspective on the origin, resistance, and spread of the emerging human fungal pathogen Candida auris
PLOS Pathogens
2023
Delineation of the Direct Contribution of Candida auris ERG11 Mutations to Clinical Triazole Resistance
Microbiology Spectrum
2021
Molecular and genetic basis of azole antifungal resistance in the opportunistic pathogenic fungusCandida albicans
Journal of Antimicrobial Chemotherapy
2019
Anti-fungal activity of a novel triazole, PC1244, against emerging azole-resistant Aspergillus fumigatus and other species of Aspergillus
Journal of Antimicrobial Chemotherapy
2019
Genomic perspective of triazole resistance in clinical and environmental Aspergillus fumigatus isolates without cyp51A mutations
Fungal Genetics and Biology
2019
In vitro combination of voriconazole with micafungin against azole-resistant clinical isolates of Aspergillus fumigatus from different geographical regions
Diagnostic Microbiology and Infectious Disease
2018
Investigation of Multiple Resistance Mechanisms in Voriconazole-Resistant Aspergillus flavus Clinical Isolates from a Chest Hospital Surveillance in Delhi, India
Antimicrobial Agents and Chemotherapy
2018
Molecular bases of antifungal resistance in filamentous fungi
International Journal of Antimicrobial Agents
2017
Whole Genome-Based Amplified Fragment Length Polymorphism Analysis Reveals Genetic Diversity in Candida africana
Frontiers in Microbiology
2017
Arabidopsis CBL interacting protein kinase 3 interacts with ABR1, an APETALA2 domain transcription factor, to regulate ABA responses
Plant Science
2017
Azole Resistance in Moulds—Approach to Detection in a Clinical Laboratory
Current Fungal Infection Reports
2016
Diversity and origins of Indian multi‐triazole resistant strains of Aspergillus fumigatus
Mycoses
2016
Evidence of genotypic diversity among Candida auris isolates by multilocus sequence typing, matrix-assisted laser desorption ionization time-of-flight mass spectrometry and amplified fragment length polymorphism
Clinical Microbiology and Infection
2016
Whole genome sequencing of emerging multidrug resistant Candida auris isolates in India demonstrates low genetic variation
New Microbes and New Infections
2016
Draft Genome Sequence of a Fluconazole-Resistant Candida auris Strain from a Candidemia Patient in India
Genome Announcements
2015
Triazole-resistant Aspergillus fumigatus harbouring G54 mutation: Is it de novo or environmentally acquired?
Journal of Global Antimicrobial Resistance
2015
Prevalence and mechanism of triazole resistance in Aspergillus fumigatus in a referral chest hospital in Delhi, India and an update of the situation in Asia
Frontiers in Microbiology
2015
Molecular Epidemiology and In-Vitro Antifungal Susceptibility of Aspergillus terreus Species Complex Isolates in Delhi, India: Evidence of Genetic Diversity by Amplified Fragment Length Polymorphism and Microsatellite Typing
PLOS ONE
2015
Exploring azole antifungal drug resistance in Aspergillus fumigatus with special reference to resistance mechanisms
Future Microbiology
2014
Multilocus sequence typing of Candida africana from patients with vulvovaginal candidiasis in New Delhi, India
Mycoses
2014
Azole-resistant Aspergillus fumigatus with the environmental TR46/Y121F/T289A mutation in India
Journal of Antimicrobial Chemotherapy
2013
Multi-azole-resistant Aspergillus fumigatus in the environment in Tanzania
Journal of Antimicrobial Chemotherapy
2014
New Clonal Strain ofCandida auris, Delhi, India
Emerging Infectious Diseases
2013
Candida nivariensis as an etiologic agent of vulvovaginal candidiasis in a tertiary care hospital of New Delhi, India
Diagnostic Microbiology and Infectious Disease
2013

Education

V. P. Chest Institute, University of Delhi

Ph.D., Medical Mycology / July, 2018

Delhi

Experience

University of Texas Health Science Center at San Antonio

Postdoctoral Fellow / March, 2020Present

University of Tennessee Health Science Center

Post Doctoral Researcher / September, 2018March, 2020

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