Javier O. Morales

Professor of drug delivery and pharmaceutical product development at University of Chile

Research Expertise

Pharmaceutics
Biotechnology
Pharmaceutical Science
Drug Discovery
Agronomy and Crop Science
Aquatic Science
Ecology
Ecology, Evolution, Behavior and Systematics
Pharmacology
Organic Chemistry
Physical and Theoretical Chemistry
Surfaces and Interfaces
Colloid and Surface Chemistry
Bioengineering
Biomedical Engineering
Development
Molecular Biology
Molecular Medicine
Clinical Biochemistry
Biochemistry
Pharmacology (medical)
Immunology
Infectious Diseases
Microbiology (medical)
Microbiology
Materials Chemistry
Inorganic Chemistry
Atomic and Molecular Physics, and Optics
Condensed Matter Physics
Spectroscopy
Electronic, Optical and Magnetic Materials

About

Javier O. Morales is a highly accomplished and experienced pharmaceutical professional with a strong academic background and extensive practical experience. He obtained his Bachelor of Science degree in Pharmacy in 2006 and the Pharmaceutical Chemist degree in 2008 from the University of Chile. He then went on to obtain his Ph.D. in Pharmaceutics from The University of Texas at Austin in 2012. Dr. Morales has since worked as an Assistant Professor and later as an Associate Professor at the University of Chile. He has also served as the Director of the Center of New Drugs for Hypertension (CENDHY), where he led a team of researchers in developing new and innovative pharmaceutical treatments for hypertension. Dr. Morales has a strong passion for research and has published numerous articles in international journals and has patented his developed technologies. His expertise in pharmaceuticals, nano and microstructured drug delivery systems, implants, and peptide drug discovery has made him a sought-after speaker at conferences and symposiums around the world. In addition to his academic and research achievements, Dr. Morales is also a dedicated mentor and has supervised and mentored several students in their research projects. He is known for his commitment to excellence and his ability to motivate and inspire others. Overall, Dr. Morales is a highly respected and accomplished pharmaceutical professional with a strong track record of success in academia. His contributions to the field of pharmaceutical sciences have made a significant impact, and he continues to be a leader in the industry.

Legacy Map

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Publications

Manufacture and characterization of mucoadhesive buccal films
European Journal of Pharmaceutics and Biopharmaceutics
2011
Challenges and Future Prospects for the Delivery of Biologics: Oral Mucosal, Pulmonary, and Transdermal Routes
The AAPS Journal
2017
Nanoparticles for diagnosis and therapy of atherosclerosis and myocardial infarction: evolution toward prospective theranostic approaches
Theranostics
2018
Overview and Future Potential of Buccal Mucoadhesive Films as Drug Delivery Systems for Biologics
AAPS PharmSciTech
2016
Effect of plasticizers on the physico-mechanical properties of pullulan based pharmaceutical oral films
European Journal of Pharmaceutical Sciences
2017
Nanoparticles for the Treatment of Wounds
Current Pharmaceutical Design
2015
Buccal delivery of small molecules and biologics: of mucoadhesive polymers, films, and nanoparticles
Current Opinion in Pharmacology
2017
Novel strategies for the buccal delivery of macromolecules
Drug Development and Industrial Pharmacy
2014
Films loaded with insulin-coated nanoparticles (ICNP) as potential platforms for peptide buccal delivery
Colloids and Surfaces B: Biointerfaces
2014
Lipid nanoparticles for the topical delivery of retinoids and derivatives
Nanomedicine
2015
Inkjet Printing of Proteins: an Experimental Approach
The AAPS Journal
2016
Characterization, phase-solubility, and molecular modeling of inclusion complex of 5-nitroindazole derivative with cyclodextrins
Bioorganic & Medicinal Chemistry
2008
Surfactants: their critical role in enhancing drug delivery to the lungs
Therapeutic Delivery
2011
The Effect of Inkjet Printing over Polymeric Films as Potential Buccal Biologics Delivery Systems
AAPS PharmSciTech
2018
Effect of surfactants and drug load on physico-mechanical and dissolution properties of nanocrystalline tadalafil-loaded oral films
European Journal of Pharmaceutical Sciences
2017
Buccal Dosage Forms: General Considerations for Pediatric Patients
AAPS PharmSciTech
2016
Inkjet printing of small molecules, biologics, and nanoparticles
International Journal of Pharmaceutics
2021
Protein-coated nanoparticles embedded in films as delivery platforms
Journal of Pharmacy and Pharmacology
2013
Magnesium-doped zinc oxide nanoparticles alter biofilm formation of Proteus mirabilis
Nanomedicine
2019
Nanomedicine and nanotoxicology: the pros and cons for neurodegeneration and brain cancer
Nanomedicine
2016
The Influence of Recrystallized Caffeine on Water-Swellable Polymethacrylate Mucoadhesive Buccal Films
AAPS PharmSciTech
2013
Development of Novel EE/Alginate Polyelectrolyte Complex Nanoparticles for Lysozyme Delivery: Physicochemical Properties and In Vitro Safety
Pharmaceutics
2019
Buccal and Sublingual Vaccines: A Review on Oral Mucosal Immunization and Delivery Systems
Vaccines
2021
Nanoparticles as Potential Novel Therapies for Urinary Tract Infections
Frontiers in Cellular and Infection Microbiology
2021
Delivery of ionizable hydrophilic drugs based on pharmaceutical formulation of ion pairs and ionic liquids
European Journal of Pharmaceutics and Biopharmaceutics
2020
Finding key nanoprecipitation variables for achieving uniform polymeric nanoparticles using neurofuzzy logic technology
Drug Delivery and Translational Research
2017
Flavonoids in Microheterogeneous Media, Relationship between Their Relative Location and Their Reactivity towards Singlet Oxygen
PLOS ONE
2015
A design of experiments to optimize a new manufacturing process for high activity protein-containing submicron particles
Drug Development and Industrial Pharmacy
2013
Drug-Loaded Lipid-Core Micelles in Mucoadhesive Films as a Novel Dosage Form for Buccal Administration of Poorly Water-Soluble and Biological Drugs
Pharmaceutics
2020
Orally disintegrating tablets and orally disintegrating mini tablets – novel dosage forms for pediatric use
Pharmaceutical Development and Technology
2019
A mechanistic approach for the optimization of loperamide loaded nanocarriers characterization: Diafiltration and mathematical modeling advantages
European Journal of Pharmaceutical Sciences
2018
Preparation of a novel lipid-core micelle using a low-energy emulsification method
Drug Delivery and Translational Research
2018
Organic and Inorganic Nanoparticles for Prevention and Diagnosis of Gastric Cancer
Current Pharmaceutical Design
2015
Poloxamer 188-Coated Ammonium Methacrylate Copolymer Nanocarriers Enhance Loperamide Permeability across Pgp-Expressing Epithelia
Molecular Pharmaceutics
2020
Poly-ε-caprolactone Nanoparticles Loaded with 4-Nerolidylcatechol (4-NC) for Growth Inhibition of Microsporum canis
Antibiotics
2020
Novel Nanostructured Polymeric Carriers to Enable Drug Delivery for Cardiovascular Diseases
Current Pharmaceutical Design
2015
Buccal delivery of small molecules and biologics: Of mucoadhesive polymers, films, and nanoparticles – An update
International Journal of Pharmaceutics
2023
Nanoparticle-Mediated Angiotensin-(1-9) Drug Delivery for the Treatment of Cardiac Hypertrophy
Pharmaceutics
2021
Nanomedicines for Brain Drug Delivery
Neuromethods
2021
Inhibition of cancer metabolism: a patent landscape
Pharmaceutical Patent Analyst
2019
Surface-Modified Nanoparticles to Improve Drug Delivery
Dekker Encyclopedia of Nanoscience and Nanotechnology, Third Edition
2014
Selected abstracts from Excipient Fest 2017
Drug Development and Industrial Pharmacy
2017
Drug Delivery Systems: Oral Mucosal
Encyclopedia of Biomedical Polymers and Polymeric Biomaterials
2015
Book Review
Drug Development and Industrial Pharmacy
2014
Structuration in the Interface of Direct and Reversed Micelles of Sucrose Esters, Studied by Fluorescent Techniques
PLOS ONE
2015
Book Review
Drug Development and Industrial Pharmacy
2014
The development of ink jet printing on textiles
Ink Jet Textile Printing
2015
Photothermal Activatable Mucoadhesive Fiber Mats for On-Demand Delivery of Insulin via Buccal and Corneal Mucosa
Unknown Venue
Los bienes humanos básicos en la doctrina de Tomás de Aquino
Intus-Legere Filosofía
2007
Improving Lurasidone Hydrochloride’s Solubility and Stability by Higher-Order Complex Formation with Hydroxypropyl-β-cyclodextrin
Pharmaceutics
2023
Experimental design and optimization of a novel dual-release drug delivery system with therapeutic potential against infection with Helicobacter pylori
Colloids and Surfaces B: Biointerfaces
2022
Mechanical Particle-Size Reduction Techniques
Formulating Poorly Water Soluble Drugs
2022
Development of a Nanostructured Lipid Carrier (NLC) by a Low-Energy Method, Comparison of Release Kinetics and Molecular Dynamics Simulation
Pharmaceutics
2021
Aptamer-functionalized lipid-core micelles loaded with rhenium tricarbonyl complex
Polyhedron
2021
Dember photovoltaic effect as method for structural characterization of phospholipidic membranes
Journal of Molecular Liquids
2021
Safety and Nanotoxicity Aspects of Nanomedicines for Brain-Targeted Drug Delivery
Neuromethods
2020
Screening of critical variables in fabricating polycaprolactone nanoparticles using Neuro Fuzzy Logic
International Journal of Pharmaceutics
2021
Buccal Delivery of Nanoparticles
Mucosal Delivery of Drugs and Biologics in Nanoparticles
2020
Light-induced release of the cardioprotective peptide angiotensin-(1–9) from thermosensitive liposomes with gold nanoclusters
Journal of Controlled Release
2020
Preface to advances in thin film technologies in drug delivery
International Journal of Pharmaceutics
2019
Formulation and Delivery of Macromolecules
AAPS PharmSciTech
2016
Mechanical Particle-Size Reduction Techniques
Formulating Poorly Water Soluble Drugs
2016
Preface for buccal drug delivery theme issue
Drug Development and Industrial Pharmacy
2014

Education

BSc, Pharmacy / November, 2006

Santiago

University of Chile

Professional Degree, PharmD / January, 2008

Santiago

The University of Texas at Austin

Ph.D., Pharmaceutics / December, 2012

Austin, Texas, United States of America

Experience

University of Chile

Assistant Professor / January, 2013October, 2019

University of Chile

Associate Professor / November, 2019Present

Center of New Drugs for Hypertension (CENDHY)

Director / December, 2019December, 2023

http://www.cendhy.cl/

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