Santosh Kumar

Assistant Professor in Vascular biology at University of Iowa

Research Expertise

Vascular endothelial function

Pharmaceutical Science

Cardiology and Cardiovascular Medicine

Toxicology

Health, Toxicology and Mutagenesis

Physiology

Physiology (medical)

Endocrinology, Diabetes and Metabolism

Internal Medicine

Pharmacology

Pharmacology (medical)

Biotechnology

Bioengineering

Biochemistry

Applied Microbiology and Biotechnology

Genetics

Molecular Biology

Genetics (clinical)

Biophysics

Cell Biology

Atomic and Molecular Physics, and Optics

Clinical Biochemistry

Public Health, Environmental and Occupational Health

Critical Care and Intensive Care Medicine

Emergency Medicine

Agronomy and Crop Science

Orthopedics and Sports Medicine

Immunology and Allergy

Immunology

Ophthalmology

Plant Science

Horticulture

Virology

Infectious Diseases

Food Science

Nutrition and Dietetics

Surgery

Drug Discovery

Organic Chemistry

Materials Chemistry

Surfaces, Coatings and Films

Condensed Matter Physics

Surfaces and Interfaces

Inorganic Chemistry

Physical and Theoretical Chemistry

Cancer Research

Spectroscopy

Biochemistry (medical)

Analytical Chemistry

Electrochemistry

Epidemiology

Pulmonary and Respiratory Medicine

Pediatrics, Perinatology and Child Health

Otorhinolaryngology

Radiology, Nuclear Medicine and imaging

Industrial and Manufacturing Engineering

Electrical and Electronic Engineering

Strategy and Management

Computer Science Applications

Information Systems and Management

Oral Surgery

Small Animals

Animal Science and Zoology

Equine

Food Animals

Publications

Alginate microspheres of isoniazid for oral sustained drug delivery

International Journal of Pharmaceutics

Oxidative stress and cardiac hypertrophy: a review

Toxicology Mechanisms and Methods

Histone and DNA Methylation–Mediated Epigenetic Downregulation of Endothelial Kruppel-Like Factor 2 by Low-Density Lipoprotein Cholesterol

Arteriosclerosis, Thrombosis, and Vascular Biology

Homocysteine promotes human endothelial cell dysfunction via site-specific epigenetic regulation of p66shc

Cardiovascular Research

Vascular microRNA-204 is remotely governed by the microbiome and impairs endothelium-dependent vasorelaxation by downregulating Sirtuin1

Nature Communications

Sirtuin1-regulated lysine acetylation of p66Shc governs diabetes-induced vascular oxidative stress and endothelial dysfunction

Proceedings of the National Academy of Sciences

Recent advances on the association of apoptosis in chronic non healing diabetic wound

World Journal of Diabetes

P66Shc-Induced MicroRNA-34a Causes Diabetic Endothelial Dysfunction by Downregulating Sirtuin1

Arteriosclerosis, Thrombosis, and Vascular Biology

Sirtuin 1 regulates cardiac electrical activity by deacetylating the cardiac sodium channel

Nature Medicine

Epigenetic upregulation of p66shc mediates low-density lipoprotein cholesterol-induced endothelial cell dysfunction

American Journal of Physiology-Heart and Circulatory Physiology

Canonical Wnt Signaling Induces Vascular Endothelial Dysfunction via p66 ^Shc -Regulated Reactive Oxygen Species

Arteriosclerosis, Thrombosis, and Vascular Biology

Catecholamine-induced myocardial fibrosis and oxidative stress is attenuated by Terminalia arjuna (Roxb.)

Journal of Pharmacy and Pharmacology

Terminalia arjuna (Arjun Tree): A Sacred plant with high Medicinal and Therapeutic Potential

Research Journal of Pharmacy and Technology

MicroRNA-204 promotes vascular endoplasmic reticulum stress and endothelial dysfunction by targeting Sirtuin1

Scientific Reports

MicroRNAs and obesity-induced endothelial dysfunction: key paradigms in molecular therapy

Cardiovascular Diabetology

A single-nucleotide variation in a p53-binding site affects nutrient-sensitive human SIRT1 expression

Human Molecular Genetics

Production of biomass, carbon dioxide, volatile acids, and their interrelationship with decrease in chemical oxygen demand, during distillery waste treatment by bacterial strains

Enzyme and Microbial Technology

Redox Factor-1 Activates Endothelial SIRTUIN1 through Reduction of Conserved Cysteine Sulfhydryls in Its Deacetylase Domain

P66Shc and vascular endothelial function

Bioscience Reports

Endothelial CaMKII as a regulator of eNOS activity and NO-mediated vasoreactivity

Effect of U50,488H, a κ-opioid receptor agonist on myocardial α-and β-myosin heavy chain expression and oxidative stress associated with isoproterenol-induced cardiac hypertrophy in rat

Molecular and Cellular Biochemistry

Peripheral benzodiazepine receptor ligand Ro5-4864 inhibits isoprenaline-induced cardiac hypertrophy in rats

European Journal of Pharmacology

Sirtuin1 protects endothelial Caveolin-1 expression and preserves endothelial function via suppressing miR-204 and endoplasmic reticulum stress

Scientific Reports

P66Shc mediates increased platelet activation and aggregation in hypercholesterolemia

Biochemical and Biophysical Research Communications

Chronic β-adrenergic activation-induced left ventricular systolic dysfunction is associated with systemic release of TNF-α and IL-1-β in rats

Pharmacological Reports

SUMO2 regulates vascular endothelial function and oxidative stress in mice

American Journal of Physiology-Heart and Circulatory Physiology

Production potential, nutrient uptake and economics of Indian mustard (Brassica juncea) under integrated nutrient management practices

The Indian Journal of Agricultural Sciences

Prevalence and association of depression in in-patient orthopaedic trauma patients: A single centre study in India

Journal of Clinical Orthopaedics and Trauma

Microbiota-governed microRNA-204 impairs endothelial function and blood pressure decline during inactivity in db/db mice

Scientific Reports

Abnormal CD161 + immune cells and retinoic acid receptor–related orphan receptor γt–mediate enhanced IL-17F expression in the setting of genetic hypertension

Journal of Allergy and Clinical Immunology

Risk factors for prolonged fatigue after recovery from COVID‐19

Journal of Medical Virology

Influence of Lactitol and Psyllium on Bowel Function in Constipated Indian Volunteers: A Randomized, Controlled Trial

Inter-hospital transfer of trauma patients in a developing country: A prospective descriptive study

International Journal of Surgery

Preparation, characterization, and biodistribution study of technetium-99m-labeled leuprolide acetate-loaded liposomes in ehrlich ascites tumor-bearing mice

Design, synthesis and anticancer activity of 2-arylimidazo[1,2-a]pyridinyl-3-amines

Bioorganic Chemistry

Behaviour of ionic liquid adsorbed on the surface of nano silica particles and in confined system of silica matrices

Surface Science

Synthesis, characterization and antibacterial activity evaluation of trinuclear Ni(II) complexes with N-substituted salicylhydrazide ligands

Registration of variety: CIM-Surabhi: A linalool rich, high essential oil yielding variety of sweet basil (Ocimum basilicum)

Journal of Medicinal and Aromatic Plant Sciences

Genetic analysis of reproductive performance of Frieswal cattle at Military Farm, Ambala

Veterinary World

Effect of Terminalia arjuna on Cardiac Hypertrophy

Bioactive Food as Dietary Interventions for Cardiovascular Disease

Pharmacological and Non-pharmacological Treatment for Decompensated Heart Failure: What Is New?

Current Heart Failure Reports

Test Method for Determination for Chemical Oxygen Demand (Manganese III Oxygen Demand) of Water

Sirtuin1 in vascular endothelial function, an overview

Machine Learning Based Prediction of Soil pH

2021 5th International Conference on Electronics, Communication and Aerospace Technology (ICECA)

Impact of Organic and Inorganic Plant Growth Promoters on Growth Indices and Yield of Wheat (Triticum aestivum L.) Varieties

Environment and Ecology

Indazole and its Derivatives in Cardiovascular Diseases: Overview, Current Scenario, and Future Perspectives

Current Topics in Medicinal Chemistry

Effect of Trichodermaharzianumstrainsand IRRI BMP on Growth, Nodulation, Yield and Economics of Lentil under Lowland Rainfed Ecology of Bihar

Journal of AgriSearch

A Correlation between Glycosylated Haemoglobin & Lipid Profile in Type-2 Diabetes Mellitus with & without Complications

International Journal of Contemporary Medicine

Method for Enhanced Separation of Cardiac Myosin Heavy Chain Isoforms by Nongradient SDS-PAGE

Analytical Letters

Quality Standards and Pharmacological Interventions of Natural Oils: Current Scenario and Future Perspectives

Enzymatic studies of bacteria used for distillery waste treatment

Enzyme and Microbial Technology

A new particle size distribution

Industrial & Engineering Chemistry Process Design and Development

Editorial: New Insights Into Oxidative Stress and Inflammation in the Pathophysiology and Treatment of Cardiovascular Diseases

Frontiers in Molecular Biosciences

Authentication and quality evaluation of an Indian traditional medicinal plant: Salparni

Annals of Phytomedicine: An International Journal

Physical activity pacifies the problematic p66Shc

European Journal of Preventive Cardiology

Correction: Corrigendum: Sirtuin1 protects endothelial Caveolin-1 expression and preserves endothelial function via suppressing miR-204 and endoplasmic reticulum stress

Scientific Reports

Performance of bacterial strains used for distillery waste treatment on different substrates

Enzyme and Microbial Technology

Functional outcome of mid-shaft clavicle fracture treated with precontoured superior plate placement: A retrospective study

Journal of Orthopaedic Diseases and Traumatology

Comparison of Carotid Intima-media Thickness between Hypertensive Patients and Control Group- A study from rural tertiary care hospital in central India

journal of medical science and clinical research

OS 02-02 microRNA-204 AND SIRTUIN1 REGULATE VASCULAR ENDOPLASMIC RETICULUM STRESS AND ENDOTHELIUM-DEPENDENT VASORELAXATION.

Journal of Hypertension

Cleidocranial Dysplasia in Son and Father: Report of Two Rare Cases with Review of Literature

Journal of Indian Academy of Oral Medicine and Radiology

P66Shc Mediates SUMO2-induced Endothelial Dysfunction

Abstract 14657: p66Shc Mediates SUMO2-Induced Endothelial Dysfunction and ROS Production

Abstract 214: Sumo2 Regulates Oxidative Function Of Adaptor Protein P66shc

Arteriosclerosis, Thrombosis, and Vascular Biology

RORγt‐Dependent Pro‐inflammatory Cytokine IL‐17F in SHR Impairs Endothelium‐Dependent Vascular Relaxation

The FASEB Journal

microRNA‐204, SIRTUIN1, and Caveolin‐1 regulate vascular endoplasmic reticulum stress and endothelium‐dependent vasorelaxation

The FASEB Journal

Abstract 14050: The Gut Flora Promotes Endothelial Dysfunction Through Vascular MicroRNA-204-mediated Down-regulation of Endothelial Sirtuin1

Abstract 14746: Dynamic SIRTUIN1-modulated Lysine Acetylation of P66shc Governs Vascular Endothelial Oxidative Stress and Dysfunction of Diabetes

A comprehensive mathematical model to calculate polish time for oxide chemical mechanical process (CMP)

International Journal of Manufacturing Technology and Management

Temporomandibular joint ankylosis—a retrospective analysis of 57 cases

International Journal of Oral and Maxillofacial Surgery

Hydrogen Production from Molasses Using Chlorinated Alkane-contaminated Groundwater as an Inoculum

95/06174 Fixed film biomethanation of distillery spentwash using low cost porous media

Fuel and Energy Abstracts

Bubaline versus bovine reproduction

Education

All India Institute of Medical Sciences

PhD, Pharmacology / February, 2010

New Delhi

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