Carolina Duarte
Multidisciplinary Biomedical Researcher
Research Expertise
About
Publications
Effects of IL‐34 and anti‐IL‐34 neutralizing mAb on alveolar bone loss in a ligature‐induced model of periodontitis
Molecular Oral Microbiology / Oct 30, 2023
Duarte, C., Yamada, C., Ngala, B., Garcia, C., Akkaoui, J., Birsa, M., Ho, A., Nusbaum, A., AlQallaf, H., John, V., & Movila, A. (2023). Effects of IL‐34 and anti‐IL‐34 neutralizing mAb on alveolar bone loss in a ligature‐induced model of periodontitis. Molecular Oral Microbiology. Portico. https://doi.org/10.1111/omi.12437
IL-34 exacerbates pathogenic features of Alzheimer’s disease and calvaria osteolysis in triple transgenic (3x-Tg) female mice
Biomedicine & Pharmacotherapy / Oct 01, 2023
Ho, A., Ngala, B., Yamada, C., Garcia, C., Duarte, C., Akkaoui, J., Ciolac, D., Nusbaum, A., Kochen, W., Efremova, D., Groppa, S., Nathanson, L., Bissel, S., Oblak, A., Kacena, M. A., & Movila, A. (2023). IL-34 exacerbates pathogenic features of Alzheimer’s disease and calvaria osteolysis in triple transgenic (3x-Tg) female mice. Biomedicine & Pharmacotherapy, 166, 115435. https://doi.org/10.1016/j.biopha.2023.115435
An Alzheimer’s disease risk variant in TTC3 modifies the actin cytoskeleton organization and the PI3K-Akt signaling pathway in iPSC-derived forebrain neurons
Neurobiology of Aging / Nov 01, 2023
Cukier, H. N., Duarte, C. L., Laverde-Paz, M. J., Simon, S. A., Van Booven, D. J., Miyares, A. T., Whitehead, P. L., Hamilton-Nelson, K. L., Adams, L. D., Carney, R. M., Cuccaro, M. L., Vance, J. M., Pericak-Vance, M. A., Griswold, A. J., & Dykxhoorn, D. M. (2023). An Alzheimer’s disease risk variant in TTC3 modifies the actin cytoskeleton organization and the PI3K-Akt signaling pathway in iPSC-derived forebrain neurons. Neurobiology of Aging, 131, 182–195. https://doi.org/10.1016/j.neurobiolaging.2023.07.007
Crosstalk between dihydroceramides produced by Porphyromonas gingivalis and host lysosomal cathepsin B in the promotion of osteoclastogenesis
Journal of Cellular and Molecular Medicine / Apr 16, 2022
Duarte, C., Yamada, C., Garcia, C., Akkaoui, J., Ho, A., Nichols, F., & Movila, A. (2022). Crosstalk between dihydroceramides produced by Porphyromonas gingivalis and host lysosomal cathepsin B in the promotion of osteoclastogenesis. Journal of Cellular and Molecular Medicine, 26(10), 2841–2851. Portico. https://doi.org/10.1111/jcmm.17299
Age-dependent effects of the recombinant spike protein/SARS-CoV-2 on the M–CSF– and IL-34-differentiated macrophages in vitro
Biochemical and Biophysical Research Communications / Mar 01, 2021
Duarte, C., Akkaoui, J., Ho, A., Garcia, C., Yamada, C., & Movila, A. (2021). Age-dependent effects of the recombinant spike protein/SARS-CoV-2 on the M–CSF– and IL-34-differentiated macrophages in vitro. Biochemical and Biophysical Research Communications, 546, 97–102. https://doi.org/10.1016/j.bbrc.2021.01.104
Potential Role of Phosphoglycerol Dihydroceramide Produced by Periodontal Pathogen Porphyromonas gingivalis in the Pathogenesis of Alzheimer’s Disease
Frontiers in Immunology / Nov 23, 2020
Yamada, C., Akkaoui, J., Ho, A., Duarte, C., Deth, R., Kawai, T., Nichols, F., Lakshmana, M. K., & Movila, A. (2020). Potential Role of Phosphoglycerol Dihydroceramide Produced by Periodontal Pathogen Porphyromonas gingivalis in the Pathogenesis of Alzheimer’s Disease. Frontiers in Immunology, 11. https://doi.org/10.3389/fimmu.2020.591571
Contribution of Porphyromonas gingivalis lipopolysaccharide to experimental periodontitis in relation to aging
GeroScience / Aug 26, 2020
Akkaoui, J., Yamada, C., Duarte, C., Ho, A., Vardar-Sengul, S., Kawai, T., & Movila, A. (2020). Contribution of Porphyromonas gingivalis lipopolysaccharide to experimental periodontitis in relation to aging. GeroScience, 43(1), 367–376. https://doi.org/10.1007/s11357-020-00258-1
Elusive Roles of the Different Ceramidases in Human Health, Pathophysiology, and Tissue Regeneration
Cells / Jun 02, 2020
Duarte, C., Akkaoui, J., Yamada, C., Ho, A., Mao, C., & Movila, A. (2020). Elusive Roles of the Different Ceramidases in Human Health, Pathophysiology, and Tissue Regeneration. Cells, 9(6), 1379. https://doi.org/10.3390/cells9061379
Efficacy of probiotics used as a periodontal treatment aid: A pilot study
The Saudi Dental Journal / Jan 01, 2019
Duarte, C., Al-Yagoob, A., & Al-Ani, A. (2019). Efficacy of probiotics used as a periodontal treatment aid: A pilot study. The Saudi Dental Journal, 31(1), 143–147. https://doi.org/10.1016/j.sdentj.2018.09.005
Prevalence and characteristics of supernumerary teeth in patients from Ras Al Khaimah: A retrospective study from a Teaching Dental Hospital in the UAE
Hamdan Medical Journal / Jan 01, 2018
Duarte, C., & Almuheiri, F. (2018). Prevalence and characteristics of supernumerary teeth in patients from Ras Al Khaimah: A retrospective study from a Teaching Dental Hospital in the UAE. Hamdan Medical Journal, 11(3), 116. https://doi.org/10.4103/hmj.hmj_20_18
Oral health risks associated with recreational and professional scuba diving: A pilot study
Hamdan Medical Journal / Jan 01, 2018
Duarte, C., & Abu-Youssef, A. (2018). Oral health risks associated with recreational and professional scuba diving: A pilot study. Hamdan Medical Journal, 11(2), 65. https://doi.org/10.4103/hmj.hmj_19_18
Hormone Relaxin as Biomarker for Bone Health and Disease
Biomarkers in Bone Disease / Jan 01, 2015
Kobayashi, Y., Duarte, C., & Moriyama, K. (2015). Hormone Relaxin as Biomarker for Bone Health and Disease. In Biomarkers in Disease: Methods, Discoveries and Applications (pp. 1–25). Springer Netherlands. https://doi.org/10.1007/978-94-007-7745-3_12-1
A preliminary investigation of the effect of relaxin on bone remodelling in suture expansion
The European Journal of Orthodontics / May 03, 2016
Duarte, C., Kobayashi, Y., Morita, J., Kawamoto, T., & Moriyama, K. (2016). A preliminary investigation of the effect of relaxin on bone remodelling in suture expansion. The European Journal of Orthodontics, cjw037. https://doi.org/10.1093/ejo/cjw037
RELAXIN enhances differentiation and matrix mineralization through Relaxin/insulin-like family peptide receptor 2 (Rxfp2) in MC3T3-E1 cells in vitro
Bone / Aug 01, 2014
Duarte, C., Kobayashi, Y., Kawamoto, T., & Moriyama, K. (2014). RELAXIN enhances differentiation and matrix mineralization through Relaxin/insulin-like family peptide receptor 2 (Rxfp2) in MC3T3-E1 cells in vitro. Bone, 65, 92–101. https://doi.org/10.1016/j.bone.2014.05.005
Relaxin receptors 1 and 2 and nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) mRNAs are expressed in oral components of developing mice
Archives of Oral Biology / Feb 01, 2014
Duarte, C., Kobayashi, Y., Kawamoto, T., & Moriyama, K. (2014). Relaxin receptors 1 and 2 and nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) mRNAs are expressed in oral components of developing mice. Archives of Oral Biology, 59(2), 111–118. https://doi.org/10.1016/j.archoralbio.2013.10.010
Education
Tokyo Medical and Dental University
PhD, Maxillofacial Orthognathics / March, 2014
Universidad Nacional Autonoma de Honduras Facultad de Odontologia
Doctor in Dental Surgery, Dentistry / November, 2008
Experience
University of Miami
Assitant Scientist
Assistant Scientist / January, 2022 — September, 2023
Nova Southeastern University
Adjunct Faculty / August, 2021 — Present
Postdoctoral Research Associate / September, 2019 — January, 2022
Ras Al Khaimah Medical and Health Sciences University College of Dental Sciences
Assistant Professor / August, 2014 — August, 2017
Tokyo Medical and Dental University
Research Assistant / April, 2011 — March, 2014
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