Este Leidmaa, PhD

Researcher in neuroscience studing cell adhesion molecules, endocannabinoid system and the BBB

Research Expertise

neuroscience
regulation of feeding behaviour
endocannabinoids
neurogenesis
astrocytes
Behavioral Neuroscience
Cell Biology
Molecular Biology
Biochemistry
Biophysics
Biological Psychiatry
Cellular and Molecular Neuroscience
Psychiatry and Mental health
Physiology
Neurology
Inorganic Chemistry
Organic Chemistry
Physical and Theoretical Chemistry
Computer Science Applications
Spectroscopy
Catalysis
Clinical Biochemistry
Pharmacology
Toxicology
Nutrition and Dietetics

Publications

Lower anxiety and a decrease in agonistic behaviour in Lsamp-deficient mice
Behavioural Brain Research
2011
Neural cell adhesion molecule Negr1 deficiency in mouse results in structural brain endophenotypes and behavioral deviations related to psychiatric disorders
Scientific Reports
2019
Enrichment and individual housing reinforce the differences in aggressiveness and amphetamine response in 129S6/SvEv and C57BL/6 strains
Behavioural Brain Research
2014
Lsamp–/– mice display lower sensitivity to amphetamine and have elevated 5-HT turnover
Biochemical and Biophysical Research Communications
2013
Gene expression patterns and environmental enrichment-induced effects in the hippocampi of mice suggest importance of Lsamp in plasticity
Frontiers in Neuroscience
2015
Cannabinoid receptor 1 signalling modulates stress susceptibility and microglial responses to chronic social defeat stress
Translational Psychiatry
2021
Blunted leptin sensitivity during hedonic overeating can be reinstated by activating galanin 2 receptors (Gal2R) in the lateral hypothalamus
Acta Physiologica
2019
Diacylglycerol lipase alpha in astrocytes is involved in maternal care and affective behaviors
Glia
2020
Modulation of feeding behavior and metabolism by dynorphin
Scientific Reports
2020
Regulation of adult neurogenesis by the endocannabinoid-producing enzyme diacylglycerol lipase alpha (DAGLa)
Scientific Reports
2022
Dynamic Changes in the Endocannabinoid System during the Aging Process: Focus on the Middle-Age Crisis
International Journal of Molecular Sciences
2022
Expression and impact of Lsamp neural adhesion molecule in the serotonergic neurotransmission system
Pharmacology Biochemistry and Behavior
2020
Brain Expression, Physiological Regulation and Role in Motivation and Associative Learning of Peroxisome Proliferator-activated Receptor γ
Neuroscience
2021
High-Fat Diet Induces Pre-Diabetes and Distinct Sex-Specific Metabolic Alterations in Negr1-Deficient Mice
Biomedicines
2021
Restoring Serotonergic Homeostasis in the Lateral Hypothalamus Rescues Sleep Disturbances Induced by Early-Life Obesity
The Journal of Neuroscience
2017
Depression-Associated Negr1 Gene-Deficiency Induces Alterations in the Monoaminergic Neurotransmission Enhancing Time-Dependent Sensitization to Amphetamine in Male Mice
Brain Sciences
2022
Autocrine regulation of adult neurogenesis by the endocannabinoid 2-arachidonoylglycerol (2-AG)
Unknown Venue
2021
Early development of hedonic and motivational aspects of eating behaviour
Appetite
2016
Epidrugs in the Therapy of Central Nervous System Disorders: A Way to Drive on?
Cells
2023

Education

Graduate School of Systemic Neuroscience and Ludwig-Maximilians-Universität München

PhD (Neurosciences), Max Planck Institute of Psychiatry / June, 2016

Munich

Georg-August Universität Göttingen

MSc (Neurosciences), International Max Planck Research School / October, 2011

Göttingen

University of Tartu

MSc (Biomedicine), Institute of Physiology / September, 2011

Tartu

University of Tartu

BA, Dept. of Psychology / June, 2008

Tartu

Experience

University of Tartu

Associate Professor / December, 2022Present

University of Bonn

Post-doctoral fellow / 2017November, 2022

Max-Planck-Institut für Psychiatrie

PhD student / September, 2011February, 2016

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