James N. Alexander IV, Ph.D.

Retired - Associate R&D Director at Dow Chemical Co

Philadelphia, Pennsylvania, United States of America

Research Expertise

Analytical Chemistry
Mass Spectrometry
Separations Science
Complex Problem Solving
Competitive Materials Characterization
Driving Innovation and Excellence in Measurement Science

About

James N. Alexander IV, Ph.D. is a highly skilled and experienced analytical chemist with over 25 years of experience in the industry. He obtained his Bachelor of Science in Chemistry from Berry College in 1982, followed by a Master of Science in Analytical Chemistry from University of Georgia in 1984. In 1999, he earned his Ph.D. in Analytical Chemistry from Uppsala Universitet. After completing his formal education, Dr. Alexander worked as a Scientist at Wyeth before joining Rohm and Haas Chemicals LLC as a Distinguished Scientist and Group Leader for Separations and MS. He then moved on to become the Associate R&D Director at Dow Chemical Co. With his vast experience and expertise in the field of analytical chemistry, Dr. Alexander started his own consulting company, JN Alexander Consulting LLC, where he serves as the Principal Consultant. He has a strong track record of developing and implementing innovative solutions for complex analytical challenges, and has contributed to numerous publications and patents in the field. Dr. Alexander is highly respected in the industry and has been recognized for his contributions with several awards and honors. He is also an active member of various professional organizations, and regularly presents at conferences and seminars. In addition to his work in the industry, he is also passionate about mentoring young scientists and has served as a guest lecturer at several universities. Award-winning, analytical scientist with substantial separation science, mass spectrometry, and technical leadership experience, with expertise in the characterization of electronic materials, emulsion polymers, and surfactants. Highly innovative and innate skill in developing new analytical technology, with ongoing connection with industry / market to continually learn and shape future innovations. Detail-oriented and organized, adept at managing and planning large scale projects that meet customer requirements, budget guidelines, and timelines. Highly collaborative and adaptable leader who builds and empowers high-performing teams and creates performance culture through process execution and talent development.

Publications

Capillary Ion Chromatography with On-Line High-Pressure Electrodialytic NaOH Eluent Production and Gradient Generation

Analytical Chemistry / Apr 01, 1997

Sjögren, A., Boring, C. B., Dasgupta, P. K., & Alexander. (1997). Capillary Ion Chromatography with On-Line High-Pressure Electrodialytic NaOH Eluent Production and Gradient Generation. Analytical Chemistry, 69(7), 1385–1391. https://doi.org/10.1021/ac961215n

Development of a nano-electrospray mass spectrometry source for nanoscale liquid chromatography and sheathless capillary electrophoresis

Rapid Communications in Mass Spectrometry / Sep 15, 1998

Alexander, J. N., Schultz, G. A., & Poli, J. B. (1998). Development of a nano-electrospray mass spectrometry source for nanoscale liquid chromatography and sheathless capillary electrophoresis. Rapid Communications in Mass Spectrometry, 12(17), 1187–1191. https://doi.org/10.1002/(sici)1097-0231(19980915)12:17<1187::aid-rcm300>3.0.co;2-t

Ultra‐high performance size‐exclusion chromatography of synthetic polymers

Journal of Separation Science / Aug 02, 2013

Janco, M., Alexander, J. N., Bouvier, E. S. P., & Morrison, D. (2013). Ultra‐high performance size‐exclusion chromatography of synthetic polymers: Demonstration of capability. Journal of Separation Science, 36(17), 2718–2727. Portico. https://doi.org/10.1002/jssc.201300444

Evaluation of Automated Isocratic and Gradient Nano-Liquid Chromatography and Capillary Electrochromatography

Analytical Chemistry / May 07, 1999

Alexander, Poli, J. B., & Markides, K. E. (1999). Evaluation of Automated Isocratic and Gradient Nano-Liquid Chromatography and Capillary Electrochromatography. Analytical Chemistry, 71(13), 2398–2409. https://doi.org/10.1021/ac981443c

Mass Distribution Measurement of Water-Insoluble Polymers by Charge-Reduced Electrospray Mobility Analysis

Analytical Chemistry / Dec 13, 2003

Ku, B. K., Fernandez de la Mora, J., Saucy, D. A., & Alexander. (2003). Mass Distribution Measurement of Water-Insoluble Polymers by Charge-Reduced Electrospray Mobility Analysis. Analytical Chemistry, 76(3), 814–822. https://doi.org/10.1021/ac034594a

Liquid chromatographic fractionation of oligomers of nonylphenyl-oligo(ethylene glycol)

Journal of Chromatography A / Jan 01, 1985

Alexander, J. N., McNally, M. E., & Rogers, L. B. (1985). Liquid chromatographic fractionation of oligomers of nonylphenyl-oligo(ethylene glycol). Journal of Chromatography A, 318, 289–298. https://doi.org/10.1016/s0021-9673(01)90689-2

Aerosol size standards in the nanometer size range

Journal of Colloid and Interface Science / Jan 01, 2006

Ude, S., Fernandez de la Mora, J., Alexander, J. N., & Saucy, D. A. (2006). Aerosol size standards in the nanometer size range. Journal of Colloid and Interface Science, 293(2), 384–393. https://doi.org/10.1016/j.jcis.2005.06.052

Evaporative light scattering detection for microcolumn liquid chromatography

Journal of Microcolumn Separations / Jan 01, 1998

Alexander, J. N. (1998). Evaporative light scattering detection for microcolumn liquid chromatography. Journal of Microcolumn Separations, 10(6), 491–502. https://doi.org/10.1002/(sici)1520-667x(1998)10:6<491::aid-mcs4>3.0.co;2-b

Coupling Charge Reduction Mass Spectrometry to Liquid Chromatography for Complex Mixture Analysis

Analytical Chemistry / Mar 21, 2016

Stutzman, J. R., Crowe, M. C., Alexander, J. N., Bell, B. M., & Dunkle, M. N. (2016). Coupling Charge Reduction Mass Spectrometry to Liquid Chromatography for Complex Mixture Analysis. Analytical Chemistry, 88(7), 4130–4139. https://doi.org/10.1021/acs.analchem.6b00485

Organic acid analysis by ion chromatography—particle beam mass spectrometry

Journal of Chromatography A / Sep 01, 1993

Alexander, J. N., & Quinn, C. J. (1993). Organic acid analysis by ion chromatography—particle beam mass spectrometry. Journal of Chromatography A, 647(1), 95–100. https://doi.org/10.1016/0021-9673(93)83328-p

Incorporation of a RAM cell in a microcolumn for on-column detection of radiolabeled molecules for LC-RAM-ESI-MS

Journal of Microcolumn Separations / Jan 01, 1998

Schultz, G. A., & Alexander, J. N. (1998). Incorporation of a RAM cell in a microcolumn for on-column detection of radiolabeled molecules for LC-RAM-ESI-MS. Journal of Microcolumn Separations, 10(5), 431–437. https://doi.org/10.1002/(sici)1520-667x(1998)10:5<431::aid-mcs6>3.0.co;2-h

An affordable high-performance pumping system for gradient capillary liquid chromatography

Journal of Microcolumn Separations / Jan 01, 1999

Kephart, T. S., Dasgupta, P. K., & Alexander, J. N. (1999). An affordable high-performance pumping system for gradient capillary liquid chromatography. Journal of Microcolumn Separations, 11(4), 299–304. https://doi.org/10.1002/(sici)1520-667x(1999)11:4<299::aid-mcs7>3.0.co;2-1

Compact, field-portable capillary ion chromatograph

Journal of Chromatography A / Apr 01, 1998

Boring, C. B., Dasgupta, P. K., & Sjögren, A. (1998). Compact, field-portable capillary ion chromatograph. Journal of Chromatography A, 804(1–2), 45–54. https://doi.org/10.1016/s0021-9673(98)00139-3

Education

Uppsala Universitet

Ph.D., Analytical Chemistry / October, 1999

Uppsala

University of Georgia

MS, Analytical Chemistry / July, 1984

Athens, Georgia, United States of America

Berry College

BS, Chemistry / June, 1982

Mount Berry, Georgia, United States of America

Experience

Dow Chemical Co

Associate R&D Director / April, 2009June, 2023

Led North American team (+50) in complex problem solving, developing, and deploying world-class measurement science solutions to accelerate value delivery, and accelerating the innovation pipeline globally across all Dow businesses through strong collaboration with R&D, Sales & Technical Service, and M&E functions.

Rohm and Haas Chemicals LLC

Distinguished Scientist / Group Leader Separations and MS / September, 1987March, 2009

Directed separation science and mass spectroscopy teams supporting the R&H technical community. Led development of new analytical techniques used in polymer, surfactant, and small molecule characterization. Strong focus on Electronic and Coating Materials.

Wyeth

Scientist / September, 1984September, 1987

JN Alexander Consulting LLC

Principal Consultant / July, 2023Present

Deliver consulting services to chemical, specialty materials, and analytical instrument companies globally. Technical expertise areas include complex problem solving, materials reverse engineering, analytical chemistry, separation science, mass spectrometry, instrument design and hyphenation, and safe laboratory operations. Leadership development across R&D, sales and technical service, and plant functions. Focused on inclusive team leadership, empowering high-performing teams, talent development, and meeting customer (internal and external) demands.

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