Colin McCaig

Regius Professor of Physiology at University of Aberdeen

About

Regius Professor of Physiology with over 30 years of experience in academic leadership, teaching, and research focused on physiological electrical signals in cell behavior, development, and wound healing. Internationally recognized for contributions to understanding how electric fields influence nerve growth, cell division, and tissue repair, with significant translational impact, including clinical applications for spinal cord injury and wound treatment. Experienced in managing large academic departments and institutes, course design, and securing continuous external research funding.

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Publications

ELECTRICAL FIELDS, CALCIUM GRADIENTS, AND CELL GROWTH
Annals of the New York Academy of Sciences
1980
The direction of growth of differentiating neurones and myoblasts from frog embryos in an applied electric field.
The Journal of Physiology
1981
The ontogeny of the transepidermal potential difference in frog embryos
Developmental Biology
1982
The distribution of lectin receptors on the plasma membrane of the fertilized sea urchin egg during first and second cleavage
Developmental Biology
1982
Motoneuron death and motor unit size during embryonic development of the rat
The Journal of Neuroscience
1984
Critical periods in rat motoneuron development
Developmental Biology
1984
A potential difference across mouse ovarian follicle
Experientia
1985
Myoblasts and myoblast‐conditioned medium attract the earliest spinal neurites from frog embryos.
The Journal of Physiology
1986
Dynamic aspects of amphibian neurite growth and the effects of an applied electric field.
The Journal of Physiology
1986
Myoblasts and notochord influence the orientation of somitic myoblasts from Xenopus laevis
Development
1986
Electric fields, contact guidance and the direction of nerve growth
Development
1986
Embryonic somatic nerve destruction with ?-bungarotoxin
Cell and Tissue Research
1987
Spinal neurite reabsorption and regrowth in vitro depend on the polarity of an applied electric field
Development
1987
On the Mechanism of Nerve Galvanotropism
The Biological Bulletin
1989
On the Mechanism of Oriented Myoblast Differentiation in an Applied Electric Field
The Biological Bulletin
1989
ENHANCED DEVELOPMENT OF STRIATED MYOFIBRILS IN XENOPUS MYOBLASTS CULTURED IN AN APPLIED ELECTRIC FIELD
Quarterly Journal of Experimental Physiology
1989
Nerve growth in the absence of growth cone filopodia and the effects of a small applied electric field
Journal of Cell Science
1989
Studies on the mechanism of embryonic frog nerve orientation in a small applied electric field
Journal of Cell Science
1989
Nerve branching is induced and oriented by a small applied electric field
Journal of Cell Science
1990
Nerve growth in a small applied electric field and the effects of pharmacological agents on rate and orientation
Journal of Cell Science
1990
Factors influencing perpendicular elongation of embryonic frog muscle cells in a small applied electric field
Journal of Cell Science
1991
Electric field‐induced orientation of rat hippocampal neurones in vitro
Experimental Physiology
1992
The effects of melanocortins and electrical fields on neuronal growth
Experimental Neurology
1992
Hippocampal growth cone responses to focally applied electric fields
Journal of Neurobiology
1993

Education

University of Glasgow, Scotland

PhD / 1980

University of Edinburgh, Scotland

B.Sc. Honours / 1975

Experience

University of Aberdeen

Regius Professor of Physiology / January, 2002December

Holds a prestigious Royal appointment. Leads research and academic activities within the physiology department, overseeing significant contributions to the field of bioelectricity.

Head of School of Medical Sciences / January, 2003December, 2015

Managed a School with 70 academic and 350 total staff. Chaired the Faculty Promotions Committee and was responsible for support documentation for national Teaching Quality Assessment (Excellent rating) and Research Assessment Exercises (top rating of 5, later 60-80% world-leading research). Appointed approximately 250 new academic staff, improving staff gender equality.

Head of School of Biomedical Sciences / January, 1998December, 2003

Managed a department with 34 academic and over 120 total staff. Oversaw departmental operations and contributed to teaching and research excellence.

Head of Institute of Medical Sciences / January, 2009December, 2011

Director of the Institute of Medical Sciences, providing leadership during a period covering sabbatical leave.

Professor, Lecturer & Researcher / January, 1986December

Developed and implemented new courses in neuroscience, physiology, cell biology, and developmental biology for medical, dental, and science students. Served as Degree Coordinator for BSc Honours Programmes (1991-1998), Departmental Examinations Officer (1991-1998), and Chair of School Examinations Board (1998-2015). Created Joint PhD with Tongji University Shanghai (2013-Present). Supervised fifteen successful PhD students and numerous postdoctoral fellows. Provided expertise in primary tissue culture, electric field application to cells, confocal microscopy, and immunocytochemistry. Secured continuous external funding for over 35 years.

Wellcome Trust University Award Lecturer / January, 1988December, 1993

Conducted research on nerve growth, filopodia, signal transduction mechanisms, and nerve branching, publishing seminal back-to-back papers.

MRC Senior Postdoctoral Fellow / January, 1986December, 1988

Independently funded research demonstrating that nerve retraction and re-growth depend on electric field polarity, with implications for spinal cord injury treatment.

University of Edinburgh

Beit Memorial Research Fellow / January, 1983December, 1986

Independent postdoctoral research establishing muscle cells produce chemoattractants and determining dynamics of filopodia on neuronal growth cones. Also involved in planning and presenting lectures at honors level and leading tutorial sessions for medical and dental students.

University of Otago, Department of Physiology

New Zealand MRC Senior Fellow / January, 1980December, 1983

Postdoctoral research on motoneurone death in mammalian embryos. Taught endocrinology and reproductive physiology courses, created and coordinated curricula, and managed lab sessions.

Universities of Colorado and Connecticut

NIH Postdoctoral Fellow / January, 1978December, 1981

Conducted research on the direction of growth of differentiating neurons and myoblasts from frog embryos in an applied electric field, a seminal work in the field.

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