I have successfully authored several grant proposals (NJ Department of Health, American Society of Hematology, WES leukemia society), top-notch scientific papers (7 peer-reviewed scientific articles and counting), technical reports (international patent deposit for anti-leukemic small inhibitors), and presented my results to world-renowned experts during national and international meetings (Outstanding Abstract Award - Federation of American Societies for Experimental Biology among the others). In a nutshell: Oncology scientist with proficiency in drug discovery, pre-clinical discovery, target validation, epigenetics. Expert in in vivo/in vitro disease and mechanistic modeling, with focus on T-cell and myeloid leukemias therapeutics. In vivo modeling of tumor generation, bone marrow transplants, PDXs, in vivo treatment, tissue sampling, necroscopy. Gene editing expertise via viral and RNP gene transduction, RNAi, gene overexpression, gene silencing, CRISPR/Cas9. Expertness in cell-based techniques, primary human samples isolation, cell culturing, aseptic techniques, drug testing. NGS assays (RNA-Seq, scRNA-Seq, ChIP-Seq), RNA assays (qPCR), DNA assays (PCR, ChIP), Protein assays (IP, WB), Flow cytometry. Critical thinker capable in managing complex scientific programs with excellent track record of scientific achievements.
Luca Tottone, Ph.D.
Oncology Scientist at the Sylvester Comprehensive Cancer Center (SCCC) - University of Miami
Research Expertise
About
Publications
Education
Sapienza University of Rome
PhD, Molecular Medicine
Sapienza University of Rome
Medical Biotechnology, Molecular Medicine
University of Teramo
Biotechnology
Experience
Sylvester Comprehensive Cancer Center
Assistant Scientist / May, 2022 — Present
Rutgers University New Brunswick
Postdoctoral Fellowship / March, 2018 — Present
Istituto Pasteur-Fondazione Cenci Bolognetti
Postdoctoral Fellowship / November, 2017 — January, 2018
Istituto Italiano di Tecnologia Center for Life Nano Science
Postdoctoral Fellowship / February, 2017 — October, 2017
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