Sakshi Gera

Research scientist with experience in biotech startup. Published in high end journals

Research Expertise

Endocrinology
Immunotherapy

Publications

Astrocytic β 2 -adrenergic receptors mediate hippocampal long-term memory consolidation
Proceedings of the National Academy of Sciences
2016
FSH blockade improves cognition in mice with Alzheimer’s disease
Nature
2022
First-in-class humanized FSH blocking antibody targets bone and fat
Proceedings of the National Academy of Sciences
2020
FSH-metabolic circuitry and menopause
Journal of Molecular Endocrinology
2019
Thyrotropin, Hyperthyroidism, and Bone Mass
The Journal of Clinical Endocrinology & Metabolism
2021
PMON51 A Single Multipurpose FSH–Blocking Therapeutic for Osteoporosis, Obesity and Alzheimer's Disease
Journal of the Endocrine Society
2022
Optimizing a therapeutic humanized follicle‐stimulating hormone–blocking antibody formulation by protein thermal shift assay
Annals of the New York Academy of Sciences
2023
Cathepsin K and Bone Resorption
Encyclopedia of Bone Biology
2020
Abstract 5894: Novel splicing-derived neoantigen in triple negative breast cancer uncovered by SpliceIO™ a robust platform for the discovery and validation of disease-specific immunotherapies
Cancer Research
2024
Abstract 5888: Novel immune-therapeutic target for lung cancer uncovered by SpliceIO™, an innovative platform that identifies disease-specific alternative splicing
Cancer Research
2024
Development and Biophysical Characterization of a Humanized FSH–Blocking Monoclonal Antibody Therapeutic Formulated at an Ultra–High Concentration
Unknown Venue
2023
SAT668 Can We Treat Osteoporosis, Obesity And Neurodegeneration With A Single FSH-blocking Drug?
Journal of the Endocrine Society
2023
SpliceIO: A robust platform for the discovery and validation of splicing-derived neoantigens.
Journal of Clinical Oncology
2023
Abstract 448: Computational discovery and experimental validation of splicing-derived neoantigens
Cancer Research
2023
Development and validation of an AI/ML platform for the discovery of splice-switching oligonucleotide targets
Unknown Venue
2022
SpliceIO™ a novel AI platform for the discovery of splicing-derived immunotherapeutic targets
European Journal of Cancer
2022
Convergence Research Unmasks Drug Targets Beyond Bone
Encyclopedia of Bone Biology
2020
RF10 | PMON205 LH/CG Receptor Activation Protects Mice from Diet-Induced Obesity and Modifies Adipose Tissue Immune Response
Journal of the Endocrine Society
2022
Author response: The hepcidin regulator erythroferrone is a new member of the erythropoiesis-iron-bone circuitry
Unknown Venue
2021
Regulation of pancreatic stellate cell activation by Notch3
BMC Cancer
2018
Crosstalk between Notch and FSH signaling, key to ovarian cancer progression
Mechanisms of Development
2017
The hepcidin regulator erythroferrone is a new member of the erythropoiesis-iron-bone circuitry
eLife
2021
Beyond bone biology: Lessons from team science
Journal of Orthopaedic Research
2020
Repurposing erectile dysfunction drugs tadalafil and vardenafil to increase bone mass
Proceedings of the National Academy of Sciences
2020
Oxytocin regulates body composition
Proceedings of the National Academy of Sciences
2019
Follicle-Stimulating Hormone Is an Autocrine Regulator of the Ovarian Cancer Metastatic Niche Through Notch Signaling
Journal of the Endocrine Society
2018
The soluble ligand Y box-1 activates Notch3 receptor by binding to epidermal growth factor like repeats 20-23
Archives of Biochemistry and Biophysics
2018
Interaction Between Cibacron Blue F3GA and Luteinizing Hormone: A Chromatographic Investigation
IOSR Journal of Pharmacy (IOSRPHR)
2012

Education

Indian Institute of Science Bangalore

Life science / July, 2017

Bengaluru

Experience

Icahn School of Medicine at Mount Sinai

Postdoctoral fellow / March, 2019January, 2022

Research Scientist / January, 2022Present

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