Gokhan Bahcecioglu

Assistant Research Professor in Bioengineering and Tissue Engineering , Breast Cancer and Aging

Research Expertise

Biomaterials and tissue engineering
breast cancer
aging
cardiac engineering
cartilage engineering
Biomaterials
Biotechnology
Bioengineering
Biochemistry
Biomedical Engineering
Molecular Biology
Structural Biology
Mechanics of Materials
Ceramics and Composites
Biophysics
Polymers and Plastics
Materials Chemistry
Modeling and Simulation
Physiology (medical)

About

Creative bioengineer with exceptional organizational skills and extensive experience in tissue engineering and regenerative medicine, 2D and 3D culture methods, **aging**, disease modeling, **spheroids/organoids**, decellularized extracellular matrices, exosomes, microRNAs, and **single cell sequencing**. Known for expertise in hydrogels, tissue engineering **breast cancer** and **aging** models, and 3D printing. Driven by sense of urgency, integrity, and accountability committed to personal and professional growth. Dedicated to **aging** research and **aging-related diseases**, especially **cancer**.

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Publications

Breast cancer models: Engineering the tumor microenvironment
Acta Biomaterialia
2020
A 3D printed PCL/hydrogel construct with zone-specific biochemical composition mimicking that of the meniscus
Biofabrication
2019
Electrically conductive 3D printed Ti3C2T MXene-PEG composite constructs for cardiac tissue engineering
Acta Biomaterialia
2022
Hydrogels of agarose, and methacrylated gelatin and hyaluronic acid are more supportive for in vitro meniscus regeneration than three dimensional printed polycaprolactone scaffolds
International Journal of Biological Macromolecules
2019
Anatomical meniscus construct with zone specific biochemical composition and structural organization
Biomaterials
2019
Effect of cellular and ECM aging on human iPSC-derived cardiomyocyte performance, maturity and senescence
Biomaterials
2021
Effects of microarchitecture and mechanical properties of 3D microporous PLLA-PLGA scaffolds on fibrochondrocyte and L929 fibroblast behavior
Biomedical Materials
2018
Hydrogels in Regenerative Medicine
Gels Handbook
2016
The Extracellular Matrix and Vesicles Modulate the Breast Tumor Microenvironment
Bioengineering
2020
Construction and in vitro testing of a multilayered, tissue-engineered meniscus
Journal of Bioactive and Compatible Polymers
2014
Human Heart Anoxia and Reperfusion Tissue (HEART) Model for the Rapid Study of Exosome Bound miRNA Expression As Biomarkers for Myocardial Infarction (Small 28/2022)
Small
2022
Immune System Effects on Breast Cancer
Cellular and Molecular Bioengineering
2021
Myocardial infarction from a tissue engineering and regenerative medicine point of view: A comprehensive review on models and treatments
Biophysics Reviews
2022
Evaluation of Hard and Soft Tissue Responses to Four Different Generation Bioresorbable Materials-Poly-l-Lactic Acid (PLLA), Poly-l-Lactic Acid/Polyglycolic Acid (PLLA/PGA), Uncalcined/Unsintered Hydroxyapatite/Poly-l-Lactic Acid (u-HA/PLLA) and Uncalcined/Unsintered Hydroxyapatite/Poly-l-Lactic Acid/Polyglycolic Acid (u-HA/PLLA/PGA) in Maxillofacial Surgery: An In-Vivo Animal Study
Materials
2023
Maternal obesity driven changes in collagen linearity of breast extracellular matrix induces invasive mammary epithelial cell phenotype
Biomaterials
2023
Systematically Engineered Go with Magnetic Cufe2o4 to Enhance Bone Regeneration on 3d Printed Pcl Scaffold
Unknown Venue
2023
An Experimental and Numerical Investigation of Cardiac Tissue-Patch Interrelation
Journal of Biomechanical Engineering
2023
Tissue failure propagation as mediated by circulatory flow
Unknown Venue
2020
Differentiation of BMSCs into Nerve Precursor Cells on Fiber-Foam Constructs for Peripheral Nerve Tissue Engineering
Journal of Siberian Federal University. Biology
2018
Yabancı Dil Olarak Türkçe Öğrenen Öğrencilerin Yazılı Anlatımlarının Yanlış Çözümleme Yaklaşımına Göre Değerlendirilmesi
Ana Dili Eğitimi Dergisi
2014
Deri Doku Mühendisliği Amaçlı Üç Boyutlu Biyobaskı ve Keratinosit Kültürü
Dicle Tıp Dergisi
2018
SAĞLIK & BİLİM 2023: Kök Hücre ve Rejeneratif Tıp-I
Unknown Venue
2023
Aged breast matrix bound vesicles promote breast cancer invasiveness
Biomaterials
2024
Engineering the cardiac tissue microenvironment
Progress in Biomedical Engineering
2023
Aged Breast Matrix Bound Vesicles Promote Breast Cancer Invasiveness
Unknown Venue
2023
Age and Sex-Dependent Differences in Human Cardiac Matrix-Bound Exosomes Modulate Fibrosis through Synergistic miRNA Effects
Unknown Venue
2022
Human Heart Anoxia and Reperfusion Tissue (HEART) Model for the Rapid Study of Exosome Bound miRNA Expression As Biomarkers for Myocardial Infarction
Small
2022
Aged Breast Extracellular Matrix Drives Mammary Epithelial Cells to an Invasive and Cancer‐Like Phenotype
Advanced Science
2021
Tissue Failure Propagation as Mediated by Circulatory Flow
Biophysical Journal
2020
Aged Breast Extracellular Matrix Drives Mammary Epithelial Cells to an Invasive and Cancer-Like Phenotype
Unknown Venue
2020
Anatomical meniscus construct with zone specific biochemical composition and structural organization
Unknown Venue
2019
Cell behavior on the alginate-coated PLLA/PLGA scaffolds
International Journal of Biological Macromolecules
2019

Education

Middle East Technical University

PhD, Biotechnology / February, 2018

Ankara

Middle East Technical University

MSc, Biotechnology / December, 2011

Ankara

Middle East Technical University

BSc, Biological Science / June, 2008

Ankara

Experience

University of Notre Dame

September, 2018Present

Orta Doğu Teknik Üniversitesi Biyoloji Bölümü

Research and Teaching Assistant / December, 2009February, 2018

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