\- High content imaging CRISPR screens \(gene silencing & gene editing\)\. \- High Content Imaging as an Early Drug Discovery Tool \(Small molecule Library screens\)\. \- Live cultures\, including live co\-cultures\. \- Neuronal assays\, including neuronal co\-cultures\, chemotaxis\, and neurotoxicity assays\. \- iPSC \-derived assays including differentiation and regeneration\. \- 3D cultures\, like Neurospheres\. \- Any multiplexed mechanism of action studies\, including co\-localization\, internalization\, morphology changes\. Software Capabilities: Harmony High-Content Imaging and Analysis Software, CellProfiler and CellProfiler Analyst, Spotfire, StratoMineR. Data management: AWS Cloud platform. Our systems produce over 3TB data/week. I manage our cloud services and investigate opportunities to reduce spend across the multi-cloud environments. #High Throughput Screening, #High-content imaging-based screens, #High throughput cell-based assay development, #Drug Development
Ranjithmenon Muraleedharan
Broad Institute of MIT and Harvard
Research Expertise
About
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Education
University of Nottingham
Ph.D, Stem cell biology, Cancer Biology and Imaging / December, 2014
University of Nottingham
MSC, MOLECULAR MEDICAL MICROBIOLOGY / September, 2007
Experience
Cincinnati Children's Hospital Medical Center
Post-Doctoral Associate / May, 2014 — April, 2018
Yale University
Associate Research Scientist / May, 2018 — October, 2021
Broad Institute of MIT & Harvard
Research Scientist / October, 2021 — Present
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