Gayan Senavirathne

Senior Research Scientist

Research Expertise

Biophysical chemistry
Bioanalytical chemistry and Single-molecule biophysics
Genetics
Molecular Biology
Genetics (clinical)
Cell Biology
Biochemistry
Biotechnology
Biophysics

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Publications

microRNAs in action: biogenesis, function and regulation
Nature Reviews Genetics
2023
Single-stranded DNA Scanning and Deamination by APOBEC3G Cytidine Deaminase at Single Molecule Resolution
Journal of Biological Chemistry
2012
Activation-induced deoxycytidine deaminase (AID) co-transcriptional scanning at single-molecule resolution
Nature Communications
2015
Widespread nuclease contamination in commonly used oxygen-scavenging systems
Nature Methods
2015
Expression and purification of nuclease-free protocatechuate 3,4-dioxygenase for prolonged single-molecule fluorescence imaging
Analytical Biochemistry
2018
Dynamic unwrapping of nucleosomes by HsRAD51 that includes sliding and rotational motion of histone octamers
Nucleic Acids Research
2016
Prototype foamy virus intasome aggregation is mediated by outer protein domains and prevented by protocatechuic acid
Scientific Reports
2019
Expression and Purification of Nuclease-Free Oxygen Scavenger Protocatechuate 3,4-Dioxygenase
Journal of Visualized Experiments
2019
Watching Aid Scanning Single Stranded and Transcribed DNA with Single Molecule Resolution
Biophysical Journal
2014
Single-Stranded DNA Scanning and Deamination by APOBEC3G with Single-Molecule Resolution
Biophysical Journal
2013
On the thermodynamic feasibility of acid-base equilibria
Unknown Venue
2024
On the thermodynamic feasibility of acid-base equilibria
Unknown Venue
2024
DNA strand breaks and gaps target retroviral intasome binding and integration
Nature Communications
2023
DNA Strand Breaks and Gaps Target Retroviral Binding and Integration
Unknown Venue
2021
Retroviral prototype foamy virus intasome binding to a nucleosome target does not determine integration efficiency
Journal of Biological Chemistry
2021
Expression and Purification of Nuclease-Free Oxygen Scavenger Protocatechuate 3,4-Dioxygenase
Journal of Visualized Experiments
2019

Education

Wayne State University

Ph.D., Chemistry / October, 2013

Detroit, Michigan, United States of America

University of Colombo

BS, Chemistry / August, 2007

Colombo
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