Alvaro Rojas-Pena

University of Michigan, Ann Arbor

Research Expertise

Transplantation
Pediatrics, Perinatology and Child Health
Surgery
Orthopedics and Sports Medicine
Electrical and Electronic Engineering
Surfaces, Coatings and Films
Metals and Alloys
Instrumentation
Condensed Matter Physics
Electronic, Optical and Magnetic Materials
Materials Chemistry
Bioengineering
Biophysics
Biomedical Engineering
Biomaterials
Fluid Flow and Transfer Processes
Colloid and Surface Chemistry
Analytical Chemistry
Drug Discovery
Molecular Medicine
Pharmaceutical Science
Advanced and Specialized Nursing
Cardiology and Cardiovascular Medicine
Radiology, Nuclear Medicine and imaging
Safety Research
Physiology (medical)
Molecular Biology
Biochemistry
Biotechnology
Clinical Biochemistry
Critical Care and Intensive Care Medicine
Pulmonary and Respiratory Medicine
Complementary and alternative medicine
Pharmacology (medical)
Physical and Theoretical Chemistry
Obstetrics and Gynecology

Legacy Map

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Publications

Donation After Circulatory Determination of Death
Transplantation
2014
Ex Situ Perfusion of Human Limb Allografts for 24 Hours
Transplantation
2017
Development of an artificial placenta I: pumpless arterio-venous extracorporeal life support in a neonatal sheep model
Journal of Pediatric Surgery
2009
The Effect of Ex Situ Perfusion in a Swine Limb Vascularized Composite Tissue Allograft on Survival up to 24 Hours
The Journal of Hand Surgery
2016
Improving blood compatibility of intravascular oxygen sensors via catalytic decomposition of S-nitrosothiols to generate nitric oxide in situ
Sensors and Actuators B: Chemical
2007
An extracorporeal artificial placenta supports extremely premature lambs for 1week
Journal of Pediatric Surgery
2015
Ex Situ Limb Perfusion System to Extend Vascularized Composite Tissue Allograft Survival in Swine
Transplantation
2015
Development of an Artificial Placenta IV
ASAIO Journal
2012
Development of an artificial placenta V: 70h veno-venous extracorporeal life support after ventilatory failure in premature lambs
Journal of Pediatric Surgery
2013
Achieving 12 Hour Normothermic Ex Situ Heart Perfusion: An Experience of 40 Porcine Hearts
ASAIO Journal
2016
Assessment of liver function during extracorporeal membrane oxygenation in the non–heart beating donor swine
Transplantation Proceedings
2004
A small-scale, rolled-membrane microfluidic artificial lung designed towards future large area manufacturing
Biomicrofluidics
2017
Normothermic Ex Vivo Heart Perfusion: Effects of Live Animal Blood and Plasma Cross Circulation
ASAIO Journal
2017
EL DERECHO A LA AUTONOMÍA POLÍTICA EN LOS PUEBLOS Y COMUNIDADES INDÍGENAS DE AMÉRICA LATINA
Los pueblos y comunidades indígenas de América Latina
2019
Improved in Vivo Performance of Amperometric Oxygen (PO2) Sensing Catheters via Electrochemical Nitric Oxide Generation/Release
Analytical Chemistry
2015
Portable Nitric Oxide (NO) Generator Based on Electrochemical Reduction of Nitrite for Potential Applications in Inhaled NO Therapy and Cardiopulmonary Bypass Surgery
Molecular Pharmaceutics
2017
Development of a wearable bioartificial kidney using the Bioartificial Renal Epithelial Cell System (BRECS)
Journal of Tissue Engineering and Regenerative Medicine
2016
Nitric oxide-releasing semi-crystalline thermoplastic polymers: preparation, characterization and application to devise anti-inflammatory and bactericidal implants
Biomaterials Science
2018
Timing of Heparin and Perfusion Temperature During Procurement of Organs with Extracorporeal Support in Donors After Circulatory Determination of Death
ASAIO Journal
2011
A selective cytopheretic inhibitory device for use during cardiopulmonary bypass surgery
Perfusion
2012
Atrial Infarction-Induced Spontaneous Focal Discharges and Atrial Fibrillation in Sheep
Circulation: Arrhythmia and Electrophysiology
2018
Ex Vivo Heart Perfusion for 72 Hours Using Plasma Cross Circulation
ASAIO Journal
2019
Cerebral Oxygenation of Premature Lambs Supported by an Artificial Placenta
ASAIO Journal
2018
Inflammatory Effects of Blood–Air Interface in a Porcine Cardiopulmonary Bypass Model
ASAIO Journal
2020
Development of an Ex-Situ Limb Perfusion System for a Rodent Model
ASAIO Journal
2019
Assessing and improving the biocompatibility of microfluidic artificial lungs
Acta Biomaterialia
2020
Gastrointestinal mucosal development and injury in premature lambs supported by the artificial placenta
Journal of Pediatric Surgery
2018
Splenic development and injury in premature lambs supported by the artificial placenta
Journal of Pediatric Surgery
2019
Extracorporeal circulatory-assisted non-heart-beating organ donation
Organ Donation and Transplantation after Cardiac Death
2009
Low-Resistance, Concentric-Gated Pediatric Artificial Lung for End-Stage Lung Failure
ASAIO Journal
2020
Evaluation of Continuous Lactate Monitoring Systems within a Heparinized In Vivo Porcine Model Intravenously and Subcutaneously
Biosensors
2018
Thrombolytic-Enhanced Extracorporeal Cardiopulmonary Resuscitation After Prolonged Cardiac Arrest
Critical Care Medicine
2016
Organ Donation After Cardiac Determination of Death (DCD): A Swine Model
ASAIO Journal
2009
Twenty-four-hour normothermic perfusion of isolated ex vivo hearts using plasma exchange
The Journal of Thoracic and Cardiovascular Surgery
2022
Novel Leukocyte Modulator Device Reduces the Inflammatory Response to Cardiopulmonary Bypass
ASAIO Journal
2019
A Novel Rotary Pulsatile Flow Pump for Cardiopulmonary Bypass
ASAIO Journal
2014
Nitric Oxide-Releasing Insert for Disinfecting the Hub Region of Tunnel Dialysis Catheters
ACS Applied Materials & Interfaces
2020
Pediatric Artificial Lung: A Low-Resistance Pumpless Artificial Lung Alleviates an Acute Lamb Model of Increased Right Ventricle Afterload
ASAIO Journal
2017
A Simple, Standard Method to Characterize Pressure/Flow Performance of Vascular Access Cannulas
ASAIO Journal
2013
Enhancing analytical accuracy of intravascular electrochemical oxygen sensors via nitric oxide release using S-nitroso-N-acetyl-penicillamine (SNAP) impregnated catheter tubing
Talanta
2019
Successful Porcine Renal Transplantation After 60 Minutes of Donor Warm Ischemia
ASAIO Journal
2015
Tidal Flow Perfusion for the Artificial Placenta: A Paradigm Shift
ASAIO Journal
2019
Large Animal Model of Pumpless Arteriovenous Extracorporeal CO2 Removal Using Room Air via Subclavian Vessels
ASAIO Journal
2016
Quantification of thermal spread and burst pressure after endoscopic vessel harvesting: A comparison of 2 commercially available devices
The Journal of Thoracic and Cardiovascular Surgery
2011
Enhanced Hemocompatibility and In Vivo Analytical Accuracy of Intravascular Potentiometric Carbon Dioxide Sensors via Nitric Oxide Release
Analytical Chemistry
2020
Long-term Effects of Hypothermic Ex Situ Perfusion on Skeletal Muscle Metabolism, Structure, and Force Generation After Transplantation
Transplantation
2019
Mechanical Circulatory Support for the Failing Fontan: Conversion to Assisted Single Ventricle Circulation—Preliminary Observations
World Journal for Pediatric and Congenital Heart Surgery
2018
In Vivo Testing of a Novel Blood Pump for Short-Term Extracorporeal Life Support
The Annals of Thoracic Surgery
2014
Nitric Oxide Attenuates the Inflammatory Effects of Air During Extracorporeal Circulation
ASAIO Journal
2019
Ex Situ Organ Preservation
Transplantation
2018
The Implantable Pediatric Artificial Lung
ASAIO Journal
2015
Prolonged (24-hour) Normothermic ex vivo Heart Perfusion Facilitated by Perfusate Hemofiltration
ASAIO Journal
2022
Lung Physiology During ECS Resuscitation of DCD Donors Followed by In Situ Assessment of Lung Function
ASAIO Journal
2009
Extracorporeal life support without systemic anticoagulation: a nitric oxide-based non-thrombogenic circuit for the artificial placenta in an ovine model
Pediatric Research
2023
Hepatic Function in Premature Lambs Supported by the Artificial Placenta and Total Parenteral Nutrition
ASAIO Journal
2022
Prolonged (≥24 Hours) Normothermic (≥32 °C) Ex Vivo Organ Perfusion: Lessons From the Literature
Transplantation
2020
Rodent Skeletal Muscle Metabolomic Changes Associated With Static Cold Storage
Transplantation Proceedings
2019
Long-Term Animal Model of Venovenous Extracorporeal Membrane Oxygenation with Atrial Septal Defect as a Bridge to Lung Transplantation
ASAIO Journal
2013
The Wearable Artificial Kidney: Is Peritoneal Dialysis the Solution?
Peritoneal Dialysis - From Basic Concepts to Clinical Excellence
2009
BIOARTIFICIAL RENAL EPITHELIAL CELL SYSTEM (BRECS): A COMPACT, CRYOPRESERVABLE EXTRACORPOREAL RENAL REPLACMENT DEVICE
Cell Medicine
2012
Toward a Servoregulation Controller to Automate CO2 Removal in Wearable Artificial Lungs
ASAIO Journal
2021
Delivery system can vary ventilatory parameters across multiple patients from a single source of mechanical ventilation
PLOS ONE
2020
Evaluation of an Anti-Thrombotic Continuous Lactate and Blood Pressure Monitoring Catheter in an In Vivo Piglet Model undergoing Open-Heart Surgery with Cardiopulmonary Bypass
Chemosensors
2020
A Model of Pediatric End-Stage Lung Failure in Small Lambs <20 kg
ASAIO Journal
2020
An Early Investigation into Possible Alternatives to Stapled Hysterotomy in Open Fetal Surgery
American Journal of Perinatology
2018
Development of a Model of Pediatric Lung Failure Pathophysiology
ASAIO Journal
2017
A Portable Servoregulation Controller to Automate CO2 Removal in Artificial Lungs
Bioengineering
2022
Ovine model of prolonged normothermic ex situ heart perfusion and support for 72 hours
Cryobiology
2018
Therapeutic Effect of Argatroban During Cardiopulmonary Resuscitation and Streptokinase During Extracorporeal Cardiopulmonary Resuscitation in a Porcine Model of Prolonged Cardiac Arrest
Critical Care Explorations
2023
Abstract 161: Impact Of Leukocyte Filtration And Leukocyte Modulation On Myocardial Injury After Prolonged Cardiac Arrest Treated With Extracorporeal Cardiopulmonary Resuscitation In A Swine Model
Circulation
2022
Novel Left Atrial Cannulation Technique for Attachment of a Pumpless Artificial Lung
ASAIO Journal
2022
Abstract 363: Examination of the Effects of Extracorporeal Cardiopulmonary Resuscitation on Sublingual Microcirculation in a Swine Model of Cardiac Arrest
Circulation
2018
Filling the Translational Gap in ARDS with a Clinically-Relevant, High-Fidelity Swine Model
A25. CRITICAL CARE: THE WIND IN THE WILLOWS - ARDS: OF SWINE AND MEN
2019
In Vivo Testing of a Novel Blood Pump for Short-Term Extracorporeal Life Support
The Journal of Heart and Lung Transplantation
2013
NORMOTHERMIC Vs. HYPOTHERMIC EXTRACORPOREAL MEMBRANE OXYGENATION (ECMO) SUPPORT DURING PROCUREMENT OF ABDOMINAL ORGANS FROM DONORS AFTER CARDIAC DEATH (DCD) IN SWINE.
Transplantation
2006
A Pumpless Pediatric Artificial Lung Maintains Function for 72 h Without Systemic Anticoagulation Using the Nitric Oxide Surface Anticoagulation System
Journal of Pediatric Surgery
2024
Artificial Intelligence-Assisted Strain Echocardiography in an Ex Vivo Heart
ASAIO Journal
2023
Twenty-Four Hour Normothermic Ex Vivo Heart Perfusion With Hemofiltration In an Adult Porcine Model
Transplantation Proceedings
2023
CARC18: Donor Heart Refusal Following Circulatory Death: An Analysis Of UNOS Refusal Codes
ASAIO Journal
2023
BIO7: PAL-LR: a Reduced Resistance, Concentric-Gated Artificial Membrane Lung for Pediatric End-Stage Lung Failure
ASAIO Journal
2023
BIO12: Toward a Wearable Extracorporeal CO2 Removal System with Integrated Exhaust Gas CO2 Sensing
ASAIO Journal
2023
BIO21: Development And Optimization Of A Novel Nitric Oxide Releasing Surface for Extracorporeal Circuits
ASAIO Journal
2023
PULM7: Toward Automatic Control Of Arterial Blood Paco2 Using Artificial Lung Exhaust Gas CO2 As A Surrogate
ASAIO Journal
2023
In Vivo Testing of an Ambient Air Based, Portable, and Automated CO2 Removal Controller for Artificial Lungs
ASAIO Journal
2023
Abstract 11924: Nicorandil Attenuates Ventricular Dysfunction in a Piglet Model of Cardiopulmonary Bypass and Cardioplegic Arrest
Circulation
2022
Normothermic Ex Vivo Perfusion with Hemofiltration Maintains Heart Performance after Prolonged Cold Ischemia Time
Journal of the American College of Surgeons
2022
Seven-day in vivo testing of a novel, low-resistance, pumpless pediatric artificial lung for long-term support
Journal of Pediatric Surgery
2022
Management Of Congenital Diaphragmatic Hernia Treated With Extracorporeal Life Support: Interim Guidelines Consensus Statement From The Extracorporeal Life Support Organization: Erratum
ASAIO Journal
2022
CARD18: Successful Transplantation of Porcine Hearts after 24 hr of Cold Ischemia Following Resuscitation using Ex Vivo Normothermic Perfusion
ASAIO Journal
2022
BIO2: Acute In Vivo Testing of a Portable Controller to Automate CO2 Removal in Artificial Lungs
ASAIO Journal
2022
CARD17: Mitigation of the Inflammatory Response During Cardiopulmonary Bypass with Nitric Oxide Gas
ASAIO Journal
2022
BIO30: A Novel Lipophilic Nitric Oxide (NO) Donor in Extracorporeal Life Support.
ASAIO Journal
2022
Abstract 14195: Impact of Leukocyte Filtration and Leukocyte Modulation on Recovery of Heart Function After Prolonged Cardiac Arrest Treated With ECPR in a Porcine Model
Circulation
2021
Development of a Novel, Low-Resistance Pediatric Artificial Lung for Long-Term Support
Pediatrics
2021
Abstract 113: Effects of Anticoagulation and Thrombolytic Therapy in a Porcine Model of Prolonged Out-of-hospital Cardiac Arrest Treated with ECPR
Circulation
2020
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