Work with Jette Jacobsen, Ph.D. | NotedSource
Associate Professor, Department of Pharmacy, University of
Copenhagen
https://cv.notedsource.io/me/8OR4744R
Jette Jacobsen, Ph.D.
Associate Professor, Department of Pharmacy, University of Copenhagen
Publications
Safety and efficacy of sodium caprate in
promoting oral drug absorption: from in
vitro to the clinic
Advanced Drug Delivery Reviews
2009
Characterising the behaviour of poorly
water soluble drugs in the intestine:
application of biorelevant media for
solubility, dissolution and transport
studies
Journal of Pharmacy and
Pharmacology
2010
TR146 cells grown on filters as a model
for human buccal epithelium: I.
Morphology, growth, barrier properties,
and permeability
International Journal of
Pharmaceutics
1995
Development and in vitro/in vivo testing
of mucoadhesive buccal patches releasing
benzydamine and lidocaine
International Journal of
Pharmaceutics
1996
Fabrication of Mucoadhesive Buccal Films
for Local Administration of Ketoprofen and
Lidocaine Hydrochloride by Combining Fused
Deposition Modeling and Inkjet Printing
Journal of Pharmaceutical
Sciences
2020
Medicated Chewing Gum
American Journal of Drug Delivery
2004
Filter‐grown TR146 cells as an in vitro
model of human buccal epithelial
permeability
European Journal of Oral Sciences
1999
The role of citric acid in oral peptide
and protein formulations: Relationship
between calcium chelation and proteolysis
inhibition
European Journal of Pharmaceutics and
Biopharmaceutics
2014
Fed and fasted state gastro-intestinal in
vitro lipolysis: In vitro in vivo
relations of a conventional tablet, a
SNEDDS and a solidified SNEDDS
European Journal of Pharmaceutical
Sciences
2014
Polymeric microcontainers improve oral
bioavailability of furosemide
International Journal of
Pharmaceutics
2016
Intestinal lymphatic transport of
halofantrine in rats assessed using a
chylomicron flow blocking approach: The
influence of polysorbate 60 and 80
European Journal of Pharmaceutical
Sciences
2008
Buccal iontophoretic delivery of
atenolol·HCl employing a new in vitro
three-chamber permeation cell
Journal of Controlled Release
2001
Cyclodextrin inclusion complexes of
antimycotics intended to act in the oral
cavity – drug supersaturation, toxicity on
TR146 cells and release from a delivery
system
European Journal of Pharmaceutics and
Biopharmaceutics
1999
Multivariate toxicity screening of
liposomal formulations on a human buccal
cell line
International Journal of
Pharmaceutics
2007
A mechanistic based approach for enhancing
buccal mucoadhesion of chitosan
International Journal of
Pharmaceutics
2014
Swelling of mucoadhesive electrospun
chitosan/polyethylene oxide nanofibers
facilitates adhesion to the sublingual
mucosa
Carbohydrate Polymers
2020
Development of simulated intestinal fluids
containing nutrients as transport media in
the Caco-2 cell culture model: Assessment
of cell viability, monolayer integrity and
transport of a poorly aqueous soluble drug
and a substrate of efflux mechanisms
European Journal of Pharmaceutical
Sciences
2007
Kolliphor Surfactants Affect
Solubilization and Bioavailability of
Fenofibrate. Studies of in Vitro Digestion
and Absorption in Rats
Molecular Pharmaceutics
2015
In vivo human buccal permeability of
nicotine
International Journal of
Pharmaceutics
2006
Development of an ex vivo retention model
simulating bioadhesion in the oral cavity
using human saliva and physiologically
relevant irrigation media
International Journal of
Pharmaceutics
2013
Buccal delivery of metformin: TR146 cell
culture model evaluating the use of
bioadhesive chitosan discs for drug
permeability enhancement
International Journal of
Pharmaceutics
2013
A novel excipient, 1-perfluorohexyloctane
shows limited utility for the oral
delivery of poorly water-soluble drugs
European Journal of Pharmaceutical
Sciences
2011
Polymer coated liposomes for use in the
oral cavity – a study of the
in vitro toxicity, effect on cell
permeability and interaction with mucin
Journal of Liposome Research
2016
In vitro, ex vivo and in vivo examination
of buccal absorption of metoprolol with
varying pH in TR146 cell culture, porcine
buccal mucosa and Göttingen minipigs
European Journal of Pharmaceutical
Sciences
2013
Cinnarizine food-effects in beagle dogs
can be avoided by administration in a Self
Nano Emulsifying Drug Delivery System
(SNEDDS)
European Journal of Pharmaceutical
Sciences
2014
Analytical aspects of printed oral dosage
forms
International Journal of
Pharmaceutics
2018
Effect of a local anesthetic lozenge in
relief of symptoms in burning mouth
syndrome
Oral Diseases
2016
Characterization of spray dried
bioadhesive metformin microparticles for
oromucosal administration
European Journal of Pharmaceutics and
Biopharmaceutics
2013
Mucoadhesive Electrospun Patch Delivery of
Lidocaine to the Oral Mucosa and
Investigation of Spatial Distribution in a
Tissue Using MALDI-Mass Spectrometry
Imaging
Molecular Pharmaceutics
2019
Acids ‘generally recognized as safe’
affect morphology and biocompatibility of
electrospun chitosan/polyethylene oxide
nanofibers
Carbohydrate Polymers
2019
Effect of food intake and
co-administration of placebo
self-nanoemulsifying drug delivery systems
on the absorption of cinnarizine in
healthy human volunteers
European Journal of Pharmaceutical
Sciences
2016
A genuine clotrimazole γ-cyclodextrin
inclusion complex-isolation, antimycotic
activity, toxicity and an unusual
dissolution rate
International Journal of
Pharmaceutics
1998
Waterborne Electrospinning of
α-Lactalbumin Generates Tunable and
Biocompatible Nanofibers for Drug Delivery
ACS Applied Nano Materials
2020
TR146 cells as a model for human buccal
epithelium: II. Optimisation and use of a
cellular sensitivity MTS/PMS assay
International Journal of
Pharmaceutics
1996
Mucin dispersions as a model for the
oromucosal mucus layer in in vitro and ex
vivo buccal permeability studies of small
molecules
European Journal of Pharmaceutics and
Biopharmaceutics
2017
Effect of cryoprotectants for maintaining
drug permeability barriers in porcine
buccal mucosa
International Journal of
Pharmaceutics
2016
Mucoadhesive Electrospun Nanofiber-Based
Hybrid System with Controlled and
Unidirectional Release of Desmopressin
International Journal of Molecular
Sciences
2022
An econazole β-cyclodextrin inclusion
complex: an unusual dissolution rate,
supersaturation, and biological efficacy
example
International Journal of
Pharmaceutics
1998
Mucoadhesive chitosan- and cellulose
derivative-based nanofiber-on-foam-on-film
system for non-invasive peptide delivery
Carbohydrate Polymers
2023
Combining in vitro and in silico methods
for better prediction of surfactant
effects on the absorption of poorly water
soluble drugs—a fenofibrate case example
International Journal of
Pharmaceutics
2014
New lidocaine lozenge as topical
anesthesia compared to lidocaine viscous
oral solution before upper
gastrointestinal endoscopy
Local and Regional Anesthesia
2012
Ex Vivo Correlation of the Permeability of
Metoprolol Across Human and Porcine Buccal
Mucosa
Journal of Pharmaceutical
Sciences
2014
Effect of bile on the oral absorption of
halofantrine in polyethylene glycol 400
and polysorbate 80 formulations dosed to
bile duct cannulated rats
Journal of Pharmacy and
Pharmacology
2011
Effects of polysorbate 80 on the in-vitro
precipitation and oral bioavailability of
halofantrine from polyethylene glycol 400
formulations in rats
Journal of Pharmacy and
Pharmacology
2010
Evaluation of the Use of Göttingen
Minipigs to Predict Food Effects on the
Oral Absorption of Drugs in Humans
Journal of Pharmaceutical
Sciences
2015
Effect of different surfactants in
biorelevant medium on the secretion of a
lipophilic compound in lipoproteins using
Caco-2 cell culture
Journal of Pharmaceutical
Sciences
2006
Electrospun α-Lactalbumin Nanofibers for
Site-Specific and Fast-Onset Delivery of
Nicotine in the Oral Cavity: An
In Vitro, Ex Vivo, and
Tissue Spatial Distribution Study
Molecular Pharmaceutics
2020
Buccal delivery of small molecules –
Impact of levulinic acid, oleic acid,
sodium dodecyl sulfate and hypotonicity on
ex vivo permeability and spatial
distribution in mucosa
European Journal of Pharmaceutics and
Biopharmaceutics
2018
Exploration of in vitro drug release
testing methods for saquinavir
microenvironmental pH modifying buccal
films
European Journal of Pharmaceutical
Sciences
2021
Buccal absorption of diazepam is improved
when administered in bioadhesive
tablets—An in vivo study in conscious
Göttingen mini-pigs
International Journal of
Pharmaceutics
2016
An Evaluation of the Physicochemical
Properties of Preservative-Free 0.005%
(w/v) Latanoprost Ophthalmic Solutions,
and the Impact on In Vitro Human
Conjunctival Goblet Cell Survival
Journal of Clinical Medicine
2022
Effect of Permeation Enhancers on the
Buccal Permeability of Nicotine: Ex vivo
Transport Studies Complemented by MALDI MS
Imaging
Pharmaceutical Research
2018
Permeability Barriers for Nicotine and
Mannitol in Porcine Buccal Mucosa Studied
by High-Resolution MALDI Mass Spectrometry
Imaging
Molecular Pharmaceutics
2018
Impact of sodium dodecyl sulphate on the
dissolution of poorly soluble drug into
biorelevant medium from drug-surfactant
discs
International Journal of
Pharmaceutics
2014
An updated and simplified method for bile
duct cannulation of rats
Laboratory Animals
2010
Impact of benzalkonium chloride-preserved
and preservative-free latanoprost eye
drops on cultured human conjunctival
goblet cells upon acute exposure and
differences in physicochemical properties
of the eye drops
BMJ Open Ophthalmology
2021
Absorption of Bupivacaine after
Administration of a Lozenge as Topical
Treatment for Pain from Oral Mucositis
Basic & Clinical Pharmacology &
Toxicology
2016
Generic benzalkonium chloride‐preserved
travoprost eye drops are not identical to
the branded polyquarternium‐1‐preserved
travoprost eye drop
Acta Ophthalmologica
2022
Polymeric Lids for Microcontainers for
Oral Protein Delivery
Macromolecular Bioscience
2019
Predicting in vivo performance of
fenofibrate amorphous solid dispersions
using in vitro non-sink dissolution and
dissolution permeation setup
International Journal of
Pharmaceutics
2021
Multi-material 3D printing of programmable
and stretchable oromucosal patches for
delivery of saquinavir
International Journal of
Pharmaceutics
2021
Microenvironmental pH modifying films for
buccal delivery of saquinavir: Effects of
organic acids on pH and drug release in
vitro
International Journal of
Pharmaceutics
2020
Visualization of the penetration modifying
mechanism of laurocapram by Mass
Spectrometry Imaging in buccal drug
delivery
European Journal of Pharmaceutical
Sciences
2019
Characterizing interregional differences
in the rheological properties and
composition of rat small intestinal mucus
Drug Delivery and Translational
Research
2024
Assessing acute colitis induced by dextran
sulfate sodium in rats and its impact on
gastrointestinal fluids
Drug Delivery and Translational
Research
2023
Characterization of burning mouth syndrome
profiles based on response to a local
anaesthetic lozenge
Oral Diseases
2020
Bupivacaine Lozenge Compared with
Lidocaine Spray as Topical Pharyngeal
Anesthetic before Unsedated Upper
Gastrointestinal Endoscopy: A Randomized,
Controlled Trial
Clinical Medicine Insights:
Gastroenterology
2014
Process development for spray drying of
sticky pharmaceuticals; case study of
bioadhesive nicotine microparticles for
compressed medicated chewing gum
International Journal of
Pharmaceutics
2013
Dissolution enhancement of griseofulvin
from griseofulvin-sodium dodecyl sulfate
discs investigated by UV imaging
Journal of Drug Delivery Science and
Technology
2017
Enhancing Buccal Drug Delivery: The Impact
of Glycerol in Slot-Die-Coated Pectin
Films
Molecular Pharmaceutics
2024
Conscious and anaesthetised Göttingen
mini-pigs as anin-vivomodel for
buccal absorption – pH-dependent
absorption of metoprolol from bioadhesive
tablets
Drug Development and Industrial
Pharmacy
2014
Azone® Decreases the Buccal Mucosal
Permeation of Diazepam in a
Concentration-Dependent Manner via a
Reservoir Effect
Journal of Pharmaceutical
Sciences
2014
In vitro and ex vivo evaluation of
bilayered effervescent microenvironmental
pH modifying buccal films with saquinavir
Journal of Drug Delivery Science and
Technology
2022
Colon targeting of fluticasone propionate
inclusion complex: a novel approach in
inflammatory bowel disease
Journal of Inclusion Phenomena and
Macrocyclic Chemistry
2012
Development of a μDissolution-Permeation
model with in situ drug concentration
monitoring
Journal of Drug Delivery Science and
Technology
2016
Cyclodextrin Inclusion Complexes of
Miconazole and Econazole—Isolation,
Toxicity on Human Cells, and Confirmation
of a New Interpretation of the Drug
Supersaturation Phenomenon
Drug Development and Industrial
Pharmacy
1999
Dissolution Model Development: Formulation
Effects and Filter Complications
Dissolution Technologies
2016
Medicated Chewing Gum
Modified-Release Drug Delivery
Technology
2002
Betaxolol Ophthalmic Solution as
Alternative Treatment for Patients with
Timolol Allergy: A Case Report
Reports
2020
The physicochemical properties of
preserved and preservative‐free
latanoprost eye drops and their impact on
human conjunctival goblet cells
Acta Ophthalmologica
2022
Achieving delayed release of freeze-dried
probiotic strains by extrusion,
spheronization and fluid bed coating -
evaluated using a three-step in vitro
model
International Journal of
Pharmaceutics
2020
Medicated Chewing Gum
Drugs and the Pharmaceutical
Sciences
2002
Kritik af den kognitive kapitalisme
Dansk Sociologi
2008
21 (10 Bl., C.)
Fragments of Roman Poetry c.60 BC–AD
20
2007
Institut for Rumforskning og -teknologi på
Danmarks Tekniske Universitet
Encyclopedia of Astrobiology
2011
Education
Ph.D., Pharmaceutics / December, 1995
Copenhagen
MSc (pharm.), Pharmaceutics / June, 1990
Copenhagen
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