Dr. Joshua Johnson, Ph.D.

Cambridge Postdoctoral Researcher with publications in DNA nanotechnology and experience with creating artificial cells.

Research Expertise

Biophysics
DNA origami
Molecular Biology
Cell Biology
Biochemistry
Biomaterials
Biotechnology
Biomedical Engineering
Condensed Matter Physics
Mechanics of Materials
Mechanical Engineering
Physiology
Ceramics and Composites
Bioengineering
Pathology and Forensic Medicine
Endocrinology
Internal Medicine
Endocrinology, Diabetes and Metabolism
Physical and Theoretical Chemistry
Electronic, Optical and Magnetic Materials
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry
Catalysis
Surgery
Cardiology and Cardiovascular Medicine
Anthropology
Health Informatics
Computer Science Applications

About

Biophysicist most recently employed at University of Cambridge as a Postdoctoral Researcher to develop DNA origami nanomachines for advanced cancer detection and integration into artificial cells. A range of diverse laboratory experiences have enabled me to fabricate, functionalize, characterize, troubleshoot, and analyze a broad range of custom equipment, devices, structures on the meso, micro, and nano scales.

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Publications

Mechanical design of DNA nanostructures
Nanoscale
2015
Integrated computer-aided engineering and design for DNA assemblies
Nature Materials
2021
Reciprocal Control of Hierarchical DNA Origami-Nanoparticle Assemblies
Nano Letters
2019
The path towards functional nanoparticle-DNA origami composites
Materials Science and Engineering: R: Reports
2019
A quantitative model for a nanoscale switch accurately predicts thermal actuation behavior
Nanoscale
2021
Correction: Co-self-assembly of multiple DNA origami nanostructures in a single pot
Chemical Communications
2022
Probing Nucleosome Stability with a DNA Origami Nanocaliper
Unknown Venue
Reciprocal Control of Hierarchical DNA Origami-Nanoparticle Assemblies
Biophysical Journal
2020
Erratum: “Compact quantum dot surface modification to enable emergent behaviors in quantum dot-DNA composites” [J. Chem. Phys. 151, 144706 (2019)]
The Journal of Chemical Physics
2020
Integrating computer-aided engineering and computer-aided design for DNA assemblies
Unknown Venue
2020
Self-Assembly of Geometry-Based DNA Origami-Histone Protein Hybrid Nanostructures for Constructing Rationally-Designed Higher-Order Structures
Unknown Venue
Dynamic Control of DNA Origami Nanostructures via Gold Nanoparticles
Biophysical Journal
2016
Co-self-assembly of multiple DNA origami nanostructures in a single pot
Chemical Communications
2021
Compact quantum dot surface modification to enable emergent behaviors in quantum dot-DNA composites
The Journal of Chemical Physics
2019

Education

Colorado School of Mines

MS Applied Physics, Physics

Golden, Colorado, United States of America

Colorado School of Mines

BS Physics Engineering, Physics / May, 2014

Golden, Colorado, United States of America

The Ohio State University

Ph.D., Biophysics / January, 2020

Columbus, Ohio, United States of America

Experience

Imperial College London

Research Associate / March, 2020 — Present

Designed, built, and programmed custom instrumentation needed for precise and varied annealing protocols as cheaper and higher throughput alternative to existing equipment. Designed novel methods for integrating DNA nanomachines with artificial cells and nanopores for enhanced cancer detection

The Ohio State University

Graduate Research Associate / May, 2014 — February, 2020

Research focused on design and characterization of DNA origami nanomachines. Emphasis on combining organic and inorganic nanomaterials using thermal or optical inputs as control mechanisms for dynamic DNA nanostructures.

University of Cambridge

Postdoctoral Research Associate / October, 2022 — April, 2023

Transferred from Imperial College to continue with research in DNA nanotechnology. During the moving process I helped establish laboratory infrastructure including the development and approval of standard operating procedures and safety protocols to ensure compliance with regulations within the Department of Chemical Engineering and Biotechnology.

Links & Social Media

Research Web Site

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