Colleen Pike

PhD Scientist with 9+ years experience in cell and molecular biology

Research Expertise

Microbiology (medical)
Immunology
Microbiology
Infectious Diseases
Cell Biology
Biochemistry
Molecular Biology
Immunology and Allergy
Parasitology
Genetics
Biotechnology

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Publications

Clostridioides difficile exploits toxin-mediated inflammation to alter the host nutritional landscape and exclude competitors from the gut microbiota
Nature Communications
2021
Legionella Effector AnkX Disrupts Host Cell Endocytic Recycling in a Phosphocholination-Dependent Manner
Frontiers in Cellular and Infection Microbiology
2017
The Legionella effector RavD binds phosphatidylinositol-3-phosphate and helps suppress endolysosomal maturation of the Legionella-containing vacuole
Journal of Biological Chemistry
2019
Mechanisms of Colonization Resistance Against Clostridioides difficile
The Journal of Infectious Diseases
2020
Tauroursodeoxycholic Acid Inhibits Clostridioides difficile Toxin-Induced Apoptosis
Infection and Immunity
2022
Exploitation of Phosphoinositides by the Intracellular Pathogen,Legionella pneumophila
Pathogenic Bacteria
2020
The microbial derived bile acid lithocholate and its epimers inhibitClostridioides difficilegrowth and pathogenicity while sparing members of the gut microbiota
Unknown Venue
2023
Legionella pneumophila targets autophagosomes and promotes host autophagy during late infection
Unknown Venue
2021
Interactions of Legionella Effector Proteins with Host Phosphoinositide Lipids
Methods in Molecular Biology
2012
Subversion of host vesicular trafficking by phosphoinositide‐binding bacterial proteins
The FASEB Journal
2017
Pathogen‐derived biosensors for detection of phosphoinositides in mammalian cells
The FASEB Journal
2016
Characterization and optimization of variability in a human colonic epithelium culture model
Unknown Venue
2023

Education

University of Delaware

PhD, Molecular Biology / December, 2019

Newark, Delaware, United States of America
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