Jordan Woehl, Ph.D.
Scripps Research/Calibr
Research Expertise
About
Publications
Education
University of Missouri
B.S., Medicinal Chemistry / May, 2011
University of Missouri–Kansas City
M.S., Cell and Molecular Biology / May, 2013
Kansas State University
Ph.D., Biochemistry and Molecular Biophysics / May, 2017
Experience
Scripps Research
Postdoctoral Fellow / June, 2017 — March, 2020
• Elucidate the host and/or microbiome targets of anti-proteolytic proteins produced in response to distal gut inflammation • Development of covalent neutrophil elastase inhibitor/biochemical probe through small molecule sulfonyl fluoride/fluorosulfate screen • Development and mechanistic understanding of small molecule inhibitor(s) of streptopain from S. pyogenes; followed by a high-throughput lead optimization strategy using SuFEx-based chemistry
International AIDS Vaccine Initiative
Analytical Scientist I/II / April, 2020 — October, 2023
• Characterization of protein/antibody preparations using biophysical methodology • Determination of kinetic properties of antibody/antigen interactions • Antigen screening through novel, synthetic yeast-display antibody and nanobody libraries • Affinity maturation of neutralizing antibodies through yeast-display methods • Development of fluorescent pseudovirus system for library-on-library screening
Scripps Research/Calibr
Sr. Staff Scientist / October, 2023 — Present
• Characterization of protein/antibody preparations using biophysical methodology • Determination of kinetic properties of antibody/antigen interactions • Antigen screening through novel, synthetic yeast-display antibody and nanobody libraries • Affinity maturation of neutralizing antibodies through yeast-display methods
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