John Joe

Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK

Research Expertise

microbiology
systems biology
genetics
quantum biology
Management of Technology and Innovation
Microbiology (medical)
Developmental Biology
Neurology (clinical)
Molecular Biology
Cognitive Neuroscience
Developmental Neuroscience
Atomic and Molecular Physics, and Optics
Applied Mathematics
Modeling and Simulation
Statistics and Probability
Clinical Biochemistry
Drug Discovery
Pharmacology
Molecular Medicine
Biochemistry
Virology
Immunology
Parasitology
Gastroenterology
Psychiatry and Mental health
Neurology
Clinical Psychology
Experimental and Cognitive Psychology
Applied Microbiology and Biotechnology
Bioengineering
Biotechnology
Immunology and Allergy
Infectious Diseases
Astronomy and Astrophysics
Statistical and Nonlinear Physics
Mechanical Engineering
Mechanics of Materials
Electrochemistry
Condensed Matter Physics
Biomaterials
Electronic, Optical and Magnetic Materials
Pharmacology (medical)
Hepatology
Electrical and Electronic Engineering
Cell Biology
Public Health, Environmental and Occupational Health
Computational Theory and Mathematics
Cellular and Molecular Neuroscience
Ecology
Ecology, Evolution, Behavior and Systematics
Biomedical Engineering
Computer Science Applications
Food Science
Structural Biology

Legacy Map

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Publications

Sequence and characteristics or IS900, an insertion element identified in a human Crohn's disease isolate orMycobacterium paratuberculosis
Nucleic Acids Research
1989
Use of highly specific DNA probes and the polymerase chain reaction to detect Mycobacterium paratuberculosis in Johne's disease
Journal of Clinical Microbiology
1990
Life on the edge: the coming of age of quantum biology
Choice Reviews Online
2016
Detection of mycobacterial DNA in sarcoidosis and tuberculosis with polymerase chain reaction
The Lancet
1992
Crohn's disease-isolated mycobacteria are identical to Mycobacterium paratuberculosis, as determined by DNA probes that distinguish between mycobacterial species
Journal of Clinical Microbiology
1987
Triple functionalisation of single-walled carbon nanotubes with doxorubicin, a monoclonal antibody, and a fluorescent marker for targeted cancer therapy
Carbon
2009
Quantum Evolution: How Physics’ Weirdest Theory Explains Life’s Biggest Mystery. By Johnjoe  McFadden. New York: W. W. Norton. $16.95 (paper). xiii + 338 p; ill.; index. ISBN: 0–393–32301–2. 2000.
The Quarterly Review of Biology
2002
Synchronous firing dynamics in a heterogeneous neurosecretory-cell population in an insect
Brain Research
2002
GSMN-TB: a web-based genome-scale network model of Mycobacterium tuberculosis metabolism
Genome Biology
2007
Biologically distinct subtypes of Mycobacterium avium differ in possession of insertion sequence IS901
Journal of Clinical Microbiology
1992
Higher Dispersion Efficacy of Functionalized Carbon Nanotubes in Chemical and Biological Environments
ACS Nano
2010
PCR of peripheral blood for diagnosis of meningococcal disease
Journal of Clinical Microbiology
1996
IS901, a new member of a widespread class of atypical insertion sequences, is associated with pathogenicity inMycobacterium avium
Molecular Microbiology
1991
Polymerase chain reaction for diagnosis of meningococcal meningitis
The Lancet
1992
Conscious Electromagnetic (CEMI) Field Theory
NeuroQuantology
2007
Drug loading, dispersion stability, and therapeutic efficacy in targeted drug delivery with carbon nanotubes
Carbon
2012
The Genetic Requirements for Fast and Slow Growth in Mycobacteria
PLoS ONE
2009
A quantum mechanical model of adaptive mutation
Biosystems
1999
Mycobacterium tuberculosis DNA in tissue affected by sarcoidosis.
BMJ
1993
Carbon flux rerouting during Mycobacterium tuberculosis growth arrest
Molecular Microbiology
2010
The origins of quantum biology
Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences
2018
13C-Flux Spectral Analysis of Host-Pathogen Metabolism Reveals a Mixed Diet for Intracellular Mycobacterium tuberculosis
Chemistry & Biology
2013
The use of DNA probes identifying restriction-fragment-length polymorphisms to examine the Mycobacterium avium complex
Molecular Microbiology
1987
13C Metabolic Flux Analysis Identifies an Unusual Route for Pyruvate Dissimilation in Mycobacteria which Requires Isocitrate Lyase and Carbon Dioxide Fixation
PLoS Pathogens
2011
Specific detection of Mycobacterium paratuberculosis DNA associated with granulomatous tissue in Crohn's disease.
Gut
1994
DNA PROBES DEMONSTRATE A SINGLE HIGHLY CONSERVED STRAIN OF MYCOBACTERIUM AVIUM INFECTING AIDS PATIENTS
The Lancet
1989
Identification of spheroplast-like agents isolated from tissues of patients with Crohn's disease and control tissues by polymerase chain reaction
Journal of Clinical Microbiology
1993
Integrating information in the brain’s EM field: the cemi field theory of consciousness
Neuroscience of Consciousness
2020
Mycobacterium tuberculosis strains disrupted in mce3 and mce4 operons are attenuated in mice
Journal of Medical Microbiology
2008
Polymerase chain reaction for detection of Mycobacterium leprae in nasal swab specimens
Journal of Clinical Microbiology
1993
Activity of mycobacterial promoters during intracellular and extracellular growth
Microbiology
1995
Modeling and simulation of the main metabolism in Escherichia coli and its several single-gene knockout mutants with experimental verification
Microbial Cell Factories
2010
Recombination in mycobacteria
Molecular Microbiology
1996
Determination of Genome Size and DNA Homology between an Unclassified Mycobacterium Species Isolated from Patients with Crohn's Disease and Other Mycobacteria
Microbiology
1987
Characterization of the virulence of Mycobacterium avium complex (MAC) isolates in mice
Clinical and Experimental Immunology
1994
Compiling a Molecular Inventory for Mycobacterium bovis BCG at Two Growth Rates: Evidence for Growth Rate-Mediated Regulation of Ribosome Biosynthesis and Lipid Metabolism
Journal of Bacteriology
2005
Simple enzymic method for isolation of DNA from diverse bacteria
Journal of Microbiological Methods
1989
Identification of proteins from tuberculin purified protein derivative (PPD) by LC-MS/MS
Tuberculosis
2009
Gene replacement by homologous recombination in Mycobacterium bovis BCG
Molecular Microbiology
1995
Recombinant Mycobacterium bovis BCG Expressing the Sm14 Antigen of Schistosoma mansoni Protects Mice from Cercarial Challenge
Infection and Immunity
2004
Quantum Biology: An Update and Perspective
Quantum Reports
2021
Generation and characterization of a PhoP homologue mutant of Neisseria meningitidis
Molecular Microbiology
2004
Mycobacteria in Crohn's disease: DNA probes identify the wood pigeon strain of Mycobacterium avium and Mycobacterium paratuberculosis from human tissue
Journal of Clinical Microbiology
1992
The Acute-Phase Reactant C-Reactive Protein Binds to Phosphorylcholine-Expressing Neisseria meningitidis and Increases Uptake by Human Phagocytes
Infection and Immunity
2008
Generation of Chemically Unmodified Pure Single-Walled Carbon Nanotubes by Solubilizing with RNA and Treatment with Ribonuclease A
Advanced Materials
2006
The magnetic immuno-polymerase chain reaction assay for the detection of Campylobacter in milk and poultry
Letters in Applied Microbiology
1996
Transcriptomic Analysis Identifies Growth Rate Modulation as a Component of the Adaptation of Mycobacteria to Survival inside the Macrophage
Journal of Bacteriology
2007
Uptake and Release of Double-Walled Carbon Nanotubes by Mammalian Cells
Advanced Functional Materials
2010
Construction and use of integrative vectors to express foreign genes in mycobacteria
Molecular Microbiology
1993
Quadruple antimycobacterial chemotherapy in Crohn's disease: results at 9 months of a pilot study in 20 patients
Alimentary Pharmacology & Therapeutics
2007
AFM imaging of functionalized carbon nanotubes on biological membranes
Nanotechnology
2009
Optimising DNA binding to carbon nanotubes by non-covalent methods
Carbon
2011
Systems-Based Approaches to Probing Metabolic Variation within the Mycobacterium tuberculosis Complex
PLoS ONE
2013
IS900-promoted stable integration of a foreign gene into mycobacteria
Molecular Microbiology
1991
Investigation of mycobacteria in Crohn's disease tissue by Southern blotting and DNA hybridisation with cloned mycobacterial genomic DNA probes from a Crohn's disease isolated mycobacteria.
Gut
1988
Design of double-walled carbon nanotubes for biomedical applications
Nanotechnology
2012
Towards the Immunoproteome of Neisseria meningitidis
PLoS ONE
2009
Infection with an Avirulent phoP Mutant of Neisseria meningitidis Confers Broad Cross-Reactive Immunity
Infection and Immunity
2004
Infrequent Transmission of Double-stranded RNA Virus Particles but Absence of DNA Proviruses in Single Ascospore Cultures of Gaeumannomyces graminis
Journal of General Virology
1983
Intracellular Mycobacterium tuberculosis Exploits Multiple Host Nitrogen Sources during Growth in Human Macrophages
Cell Reports
2019
Auxotrophic complementation as a selectable marker for stable expression of foreign antigens in Mycobacterium bovis BCG
Tuberculosis
2007
Identification and characterization of a novel insertion sequence, IS1106, downstream of the porA gene in B15 Neisseria meningitidis
Molecular Microbiology
1992
Context-sensitive transposition of IS6110 in mycobacteria
Microbiology
1999
Stimulation of transposition of the Mycobacterium tuberculosis insertion sequence IS6110 by exposure to a microaerobic environment
Molecular Microbiology
1999
Genus- and species-specific DNA probes to identify mycobacteria using the polymerase chain reaction
Molecular and Cellular Probes
1990
A microfluidic system for long-term time-lapse microscopy studies of mycobacteria
Tuberculosis
2012
Mycobacteria and Crohn's disease.
Gut
1988
Naturally occurring insertional inactivation of theporAgene ofNeisseria meningitidisby integration of IS1301
Molecular Microbiology
1998
DNA fingerprinting as an indicator of active transmission of multidrug-resistant tuberculosis in Poland
International Journal of Infectious Diseases
1998
Interrogation of global mutagenesis data with a genome scale model of Neisseria meningitidis to assess gene fitness in vitro and in sera
Genome Biology
2011
Phenotypic and Transcriptional Characterization of the Meningococcal PhoPQ System, a Magnesium-Sensing Two-Component Regulatory System That Controls Genes Involved in Remodeling the Meningococcal Cell Surface
Journal of Bacteriology
2005
Escape From Evolutionary Stasis by Transposon-mediated Deleterious Mutations
Journal of Theoretical Biology
1997
Properties of Thirteen Viruses and Virus Variants Obtained from Eight Isolates of the Wheat Take-All Fungus, Gaeumannomyces graminis var. tritici.
Journal of General Virology
1981
Chloroquine-enhanced gene delivery mediated by carbon nanotubes
Carbon
2011
Comparative evaluation of Mycobacterium vaccae as a surrogate cloning host for use in the study of mycobacterial genetics
Microbiology
2002
The anaplerotic node is essential for the intracellular survival of Mycobacterium tuberculosis
Journal of Biological Chemistry
2018
Epidemiological and genetic markers, virulence factors and intracellular growth of Mycobacterium avium in AIDS
Research in Microbiology
1992
Mycobacterial DNA not detected in liver sections from patients with primary biliary cirrhosis
Journal of Hepatology
1998
Slow Protein Fluctuations Explain the Emergence of Growth Phenotypes and Persistence in Clonal Bacterial Populations
PLoS ONE
2013
Expression of the B-cell and T-cell epitopes of the rabies virus nucleoprotein in Mycobacterium bovis BCG and induction of an humoral response in mice
Vaccine
2001
Integrating Kinetic Model of E. coli with Genome Scale Metabolic Fluxes Overcomes Its Open System Problem and Reveals Bistability in Central Metabolism
PLOS ONE
2015
Differential Producibility Analysis (DPA) of Transcriptomic Data with Metabolic Networks: Deconstructing the Metabolic Response of M. tuberculosis
PLoS Computational Biology
2011
PCR-single-stranded confirmational polymorphism analysis for non-culture-based subtyping of meningococcal strains in clinical specimens
Journal of Clinical Microbiology
1997
No evidence for antibodies to mycobacterial A60 antigen in Crohn's disease sera by enzyme-linked immunoabsorbent assay (ELISA)
Journal of Medical Microbiology
1988
Academic Press Geology Series
Quantitative Methods
1990
Protamine and Chloroquine Enhance Gene Delivery and Expression Mediated by RNA-Wrapped Single Walled Carbon Nanotubes
Journal of Nanoscience and Nanotechnology
2012
Mycobacteria as possible causes of sarcoidosis and Crohn's disease
Journal of Applied Bacteriology
1996
MUFINS: multi-formalism interaction network simulator
npj Systems Biology and Applications
2016
New Recombinant Mycobacterium bovis BCG Expression Vectors: Improving Genetic Control over Mycobacterial Promoters
Applied and Environmental Microbiology
2016
Updating and curating metabolic pathways of TB
Tuberculosis
2013
Cellular localization, accumulation and trafficking of double-walled carbon nanotubes in human prostate cancer cells
Nano Research
2012
Modeling the binding of peptides on carbon nanotubes and their use as protein and DNA carriers
Journal of Nanoparticle Research
2012
Transposon libraries identify novel Mycobacterium bovis BCG genes involved in the dynamic interactions required for BCG to persist during in vivo passage in cattle
BMC Genomics
2019
System-level strategies for studying the metabolism of Mycobacterium tuberculosis
Molecular BioSystems
2010
Acorn: A grid computing system for constraint based modeling and visualization of the genome scale metabolic reaction networks via a web interface
BMC Bioinformatics
2011
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