Dushani L. Palliyaguru, Ph.D.
Toxicologist | Aging, Nutrition and Metabolism Research Scientist | Systems Biologist
Research Expertise
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Education
University of Pittsburgh
Ph.D., Environmental and Occupational Health (Toxicology) / May, 2016
Clark University
B.A., Biochemistry and Molecular Biology, Mathematics / May, 2009
Experience
National Institute on Aging Intramural Research Program, Translational Gerontology Branch
IRTA Postdoctoral Fellow, K99/R00 Grant Recipient / September, 2018 — Present
-Leading, managing and coordinating large population longitudinal studies within US Federal Government and Industry partnerships - Successfully writing, submitting, and managing grants and manuscripts to ensure continuity of research initiatives -Hiring, mentoring, and supervising research fellows and technicians -Applying epidemiological, machine learning and data science methods to multi-omics data to characterize biomarkers of aging and aging-related diseases -Testing nutritional and pharmacological compounds for lifespan extension, and prevention of chronic diseases (eg. Alzheimer’s)
University of Pittsburgh, Department of Pharmacology and Chemical Biology
Postdoctoral Fellow / May, 2016 — September, 2018
Identified a novel urinary biomarker of cruciferous vegetable intake in cancer prevention clinical trials using liquid chromatography mass spectrometry -Led and managed project that showed broccoli-derived sulforaphane prevented breast cancer through altering gene expression and lipidomics profiles
Healthcare Ready
Health Policy Fellow / January, 2017 — January, 2018
-Synthesized data, mined literature and wrote Toolkits/ Issue Brief on “Pharmacy and Emergency Preparedness: A Landscape Analysis”
University of Pittsburgh, Department of Environmental and Occupational Health
Graduate Student Researcher / August, 2010 — May, 2016
-Identified gene and protein expression profiles and pharmacodynamic properties of novel chemopreventive compounds -Studied the global geographical overlap of liver cancer risk factors - aflatoxin exposure and hepatitis viruses with public health data -Evaluated the molecular basis of organ toxicity induced by acetaminophen, diquat and high fat diet and tested how interventions can prevent or minimize these toxicities
UMASS Medical School, Department of Pathology
Research Technician / May, 2009 — May, 2010
-Investigated the role of the immunoproteasome in antigen presentation in the adaptive immune system
UMASS Medical School, Department of Cancer Biology
Research Intern / May, 2007 — May, 2009
-Studied the role of insulin receptor substrate (IRS) in breast cancer metastasis in cell lines and tumors using bioinformatics software
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