Regan Hamel

Senior bioinformatics scientist, specializing in single cell omics in the context of cellular reprogramming and neuroinflammation

Cambridge

Research Expertise

single cell biology
transcriptomics
Cellular and Molecular Neuroscience
Cell Biology
Developmental Biology
Immunology
Immunology and Allergy
Drug Discovery
Pharmacology
Genetics
Molecular Biology
Molecular Medicine
History and Philosophy of Science

About

Regan Hamel has an MPhil and PhD in Clinical Neurosciences from University of Cambridge. She also has a Bachelor of Science in Neurosciences from McGill University. Her PhD with Stefano Pluchino and John Marioni focused on single cell transcriptomics in the context of neuroinflammation. Since 2021 she has worked as a Bioinformatics scientist at Mogrify Ltd, applying a multitude of computational biology techniques (including single cell omics, bulk RNAseq, and predictive modelling) in the context of cell reprogramming

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Publications

Harnessing the Neural Stem Cell Secretome for Regenerative Neuroimmunology
Frontiers in Cellular Neuroscience
2020
Stem Cell Therapies for Progressive Multiple Sclerosis
Frontiers in Cell and Developmental Biology
2021
Characterization of Human iPSC-derived Spinal Motor Neurons by Single-cell RNA Sequencing
Neuroscience
2020
Metabolic Control of Smoldering Neuroinflammation
Frontiers in Immunology
2021
Combination of In Situ Lcn2 pRNA-RNAi Nanotherapeutics and iNSC Transplantation Ameliorates Experimental SCI in Mice
Molecular Therapy
2020
Bioinformatics analysis identified apolipoprotein E as a hub gene regulating neuroinflammation in macrophages and microglia following spinal cord injury
Frontiers in Immunology
2022
Time-resolved single-cell RNAseq profiling identifies a novel Fabp5-expressing subpopulation of inflammatory myeloid cells in chronic spinal cord injury
Unknown Venue
2020
Single cell biology—a Keystone Symposia report
Annals of the New York Academy of Sciences
2021
The therapeutic potential of exogenous adult stem cells for the injured central nervous system
Handbook of Innovations in Central Nervous System Regenerative Medicine
2020
Integrative multi-omics analysis reveals molecular landscape associated with chronic lipid accumulation following contusive spinal cord injury
Unknown Venue
2023
Multiple sclerosis and neuromyelitis optica spectrum disorders
Neurobiology of Brain Disorders
2023
Time-resolved single-cell RNAseq profiling identifies a novel Fabp5+ subpopulation of inflammatory myeloid cells with delayed cytotoxic profile in chronic spinal cord injury
Heliyon
2023

Education

University of Cambridge

PhD, Clinical Neurosciences / September, 2021

Cambridge

University of Cambridge

MPhil, Clinical Neurosciences / September, 2018

Cambridge

McGill University

Bachelor of Science, Neurosciences / June, 2017

Montreal

Experience

Mogrify Ltd

Bioinformatics scientist / August, 2021June, 2023

Senior Bioinformatics Scientist / July, 2023Present

Links & Social Media

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