Dr. Matthias Steiert, Ph.D.

Consultant with 30 years of interdisciplinary R&D experience in drug discovery and material sciences

Research Expertise

nanomedicine
biomaterials
antimicrobials
cancer
biosensors
Drug Discovery
Pharmaceutical Science
Microbiology (medical)
Microbiology
Molecular Biology
Immunology and Allergy
Hematology
Immunology
Biophysics
Biochemistry
Cell Biology
Infectious Diseases
Pharmacology (medical)
Pharmacology
Biomedical Engineering
Bioengineering
Mechanical Engineering
Mechanics of Materials
Condensed Matter Physics
Applied Microbiology and Biotechnology
Biotechnology
Oncology
Medical–Surgical Nursing

About

Matthias Steiert has extensive experience with nano-scale systems both for the development of drug delivery systems and diagnostics particularly in the areas of cancer and antimicrobial disease diagnostics. He is also a consultant for various companies involved in nanotechnological applications and is cofounder of Afaf Translations LLC, a scientific language service provider. Previously, he was co-founder of Los Gatos Pharmaceuticals and before held a position as Senior Director of R&D at Matrix Sensors Inc. and prior to that 10 years of senior-level research positions at several biotechnology companies in the fields of nanotechnology, drug development, diagnostics, and blood safety in the San Francisco Bay Area. Earlier in his career, Matthias was Senior Scientist at GlaxoSmithKline (Italy), a research fellow at the National Institute of Health and Environment (The Netherlands), and a consultant for the World Health Organization. He received his postdoctoral training from the University of California, Berkeley. Matthias holds a degree in plant physiology from the University of Freiburg (Germany) and obtained his Ph.D. in biochemistry from the University of Basel (Switzerland).

Publications

Crystal structures explain functional properties of two E. coli porins

Nature / Aug 01, 1992

Cowan, S. W., Schirmer, T., Rummel, G., Steiert, M., Ghosh, R., Pauptit, R. A., Jansonius, J. N., & Rosenbusch, J. P. (1992). Crystal structures explain functional properties of two E. coli porins. Nature, 358(6389), 727–733. https://doi.org/10.1038/358727a0

Targeted nanoparticles for detecting and treating cancer

Drug Development Research / Jan 01, 2006

Sunderland, C. J., Steiert, M., Talmadge, J. E., Derfus, A. M., & Barry, S. E. (2006). Targeted nanoparticles for detecting and treating cancer. Drug Development Research, 67(1), 70–93. Portico. https://doi.org/10.1002/ddr.20069

Pharmacokinetics and biodistribution of RGD-targeted doxorubicin-loaded nanoparticles in tumor-bearing mice

International Journal of Pharmaceutics / Apr 01, 2005

Bibby, D. C., Talmadge, J. E., Dalal, M. K., Kurz, S. G., Chytil, K. M., Barry, S. E., Shand, D. G., & Steiert, M. (2005). Pharmacokinetics and biodistribution of RGD-targeted doxorubicin-loaded nanoparticles in tumor-bearing mice. International Journal of Pharmaceutics, 293(1–2), 281–290. https://doi.org/10.1016/j.ijpharm.2004.12.021

Development of a multiplex-PCR for direct detection of the genes for enterotoxin B and C, and toxic shock syndrome toxin-1 in Staphylococcus aureus isolates

Journal of Medical Microbiology / Apr 01, 1998

Schmitz, F.-J., Steiert, M., Hofmann, B., Verhoef, J., Hadding, U., Heinz, H.-P., & Kohrer, K. (1998). Development of a multiplex-PCR for direct detection of the genes for enterotoxin B and C, and toxic shock syndrome toxin-1 in Staphylococcus aureus isolates. Journal of Medical Microbiology, 47(4), 335–340. https://doi.org/10.1099/00222615-47-4-335

Secondary structure of the outer membrane proteins OmpA of Escherichia coli and OprF of Pseudomonas aeruginosa

Journal of Bacteriology / Oct 01, 1996

Sugawara, E., Steiert, M., Rouhani, S., & Nikaido, H. (1996). Secondary structure of the outer membrane proteins OmpA of Escherichia coli and OprF of Pseudomonas aeruginosa. Journal of Bacteriology, 178(20), 6067–6069. https://doi.org/10.1128/jb.178.20.6067-6069.1996

Typing of methicillin-resistant Staphylococcus aureus isolates from Dusseldorf by six genotypic methods

Journal of Medical Microbiology / Apr 01, 1998

Schmitz, F.-J., Steiert, M., Tichy, H.-V., Hofmann, B., Verhoef, J., Heinz, H.-P., Kohrer, K., & Jones, M. E. (1998). Typing of methicillin-resistant Staphylococcus aureus isolates from Dusseldorf by six genotypic methods. Journal of Medical Microbiology, 47(4), 341–351. https://doi.org/10.1099/00222615-47-4-341

Photochemical inactivation with amotosalen and long‐wavelength ultraviolet light of Plasmodium and Babesia in platelet and plasma components

Transfusion / Jul 29, 2008

Grellier, P., Benach, J., Labaied, M., Charneau, S., Gil, H., Monsalve, G., Alfonso, R., Sawyer, L., Lin, L., Steiert, M., & Dupuis, K. (2008). Photochemical inactivation with amotosalen and long‐wavelength ultraviolet light of Plasmodium and Babesia in platelet and plasma components. Transfusion, 48(8), 1676–1684. Portico. https://doi.org/10.1111/j.1537-2995.2007.01762.x

Versicor to Merge with Biosearch Italia

PharmaDeals Review / Aug 01, 2002

Review Editor, B. (2002). Versicor to Merge with Biosearch Italia. PharmaDeals Review, 2002(27). https://doi.org/10.3833/pdr.v2002i27.1024

Structural and Functional Characterization of a His-Tagged PhoE Pore Protein ofEscherichia coli

Biochemical and Biophysical Research Communications / Dec 01, 1996

Gelder, P. V., Steiert, M., Khattabi, M. E., Rosenbusch, J. P., & Tommassen, J. (1996). Structural and Functional Characterization of a His-Tagged PhoE Pore Protein ofEscherichia coli. Biochemical and Biophysical Research Communications, 229(3), 869–875. https://doi.org/10.1006/bbrc.1996.1894

Establishment of a European network for the surveillance of Mycobacterium tuberculosis, MRSA and penicillin-resistant pneumococci

Journal of Antimicrobial Chemotherapy / Nov 01, 1996

VAN EMBDEN, D. A., VAN SOOLINGEN, D., HEERSMA, H. F., DE NEELING, A. J., JONES, M. E., STEIERT, M., GREK, V., MOOI, F. R., & VERHOEF, J. (1996). Establishment of a European network for the surveillance of Mycobacterium tuberculosis, MRSA and penicillin-resistant pneumococci. Journal of Antimicrobial Chemotherapy, 38(5), 905–907. https://doi.org/10.1093/jac/38.5.905

Detection of Staphylococcal Genes Directly from Cerebrospinal and Peritoneal Fluid Samples Using a Multiplex Polymerase Chain Reaction

European Journal of Clinical Microbiology & Infectious Diseases / Jul 03, 1998

Schmitz, F.-J., Steiert, M., Hofmann, B., Fluit, A. C., Verhoef, J., Heinz, H.-P., & Jones, M. E. (1998). Detection of Staphylococcal Genes Directly from Cerebrospinal and Peritoneal Fluid Samples Using a Multiplex Polymerase Chain Reaction. European Journal of Clinical Microbiology & Infectious Diseases, 17(4), 272–274. https://doi.org/10.1007/s100960050061

Label-Free Biodetection Using Capacitive Micromachined Ultrasonic Transducers (CMUTs) and Its Application for Cardiovascular Disease Diagnostics

Journal of Nanomedicine & Nanotechnology / Jan 01, 2012

Eaimkhong, S. (2012). Label-Free Biodetection Using Capacitive Micromachined Ultrasonic Transducers (CMUTs) and Its Application for Cardiovascular Disease Diagnostics. Journal of Nanomedicine & Nanotechnology, 03(05). https://doi.org/10.4172/2157-7439.1000144

Modeling and Modal Analysis on Capacitive Micromachined Ultrasound Transducers

Applied Mechanics and Materials / Aug 18, 2014

Li, Y., & Zhang, P. Y. (2014). Modeling and Modal Analysis on Capacitive Micromachined Ultrasound Transducers. Applied Mechanics and Materials, 620, 300–303. https://doi.org/10.4028/www.scientific.net/amm.620.300

Education

PhD, Biochemistry / June, 1993

Basel

Experience

Please check my LinkedIn profile

Links & Social Media

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