Dear Sir/Madam, This is Dr. Anup Kumar Patel, who has been working as a Postdoctoral Scientist at City of Hope CA. My research involves the synthesis and characterization of polymeric (PS, PLA, and PMMA), metallic (Au, Ag), and silica nanoparticles, functionalization, hydrogels, drug delivery for cancer treatment, UV curable & 3-D printable ink for wound healing applications, bio tribology, polymeric coatings and Surface‐Enhanced Raman Scattering with nanophotonic and biomedical amplifying systems for an early diagnosis of Alzheimer’s disease pathology (functionalization of HCPCF with NPs to generate SERS for early Alzheimer’s detection). Currently, I am working on the synthesis. Efficacy and formulation optimization of various injectable polymeric hydrogel materials (cross-linked hyaluronic acid gel, peptide SIINFEKL (H-2 Kb) gel for stimulation of T cells, PLA & PLGA gel/glue/NPs, cross-linked gelatin-based gel, PLA-based drug eluting rods, etc. for targeted and controlled drug delivery in cancer treatment, etc.). I am eagerly looking for an R&D opening to use my expertise and gain more work exposure. I will be available immediately to shoulder the responsibility. ***I have a J1 VISA with validity up to Aug. 2027 and I am always open for O1 as well as H1B sponsorship for the same.*** I pursued my Ph.D. dissertation under the guidance of Professor Kantesh Balani (IIT-Kanpur India) on a most significant problem: formation of wear debris, aseptic-loosening, and implant failure associated with polymeric-based acetabular cup liner used in orthopedic-applications (THR and THR). The title of the thesis is entitled “Effect of Carbon Nanotubes and Aluminum Oxide Reinforcement on Multifunctional Properties of UHMWPE Biocomposites for Biomedical Applications”. I have done the functionalization of MWCNTs with 3-APTES, hydrothermal synthesis of ZnO particles, and reinforced in UHMWPE with the varying weight percentage of Aluminum oxide using ball milling. Fabrication of composite was done using compression molding technique and characterized for mechanical, thermal, tribological, and biological (mineralization of apatite, cell culture, and bactericidal efficacy) properties. It would be great if work involves any synthesis and fabrication of materials, surface functionalization of nano-particles, stimuli-responsive polymers, hydrogels and 3-D printing, and anti-adhesive coatings. During my Ph.D. and postdocs, I gained a confident level of experience in the fabrication of biomaterials & their characterization using various techniques: XPS, SPR, AFM, XRD, FTIR, DSC, TEM, SEM, Raman, and nanoindentation for morphological, phase stability, and mechanical properties. Simultaneously, the synthesis of carbon nanofibers, and cell culture expertise (culture studies on various material surfaces with and without modification using L929 Mouse fibroblast cell line as well as MSCs cells) work were also pursued. I also have been working for \~ 2 years as a project associate in the Dept. of Chemical & Mechanical Eng. at IIT Kanpur with Profs. Y.M. Joshi, Ashutosh Sharma, and Sumit Basu respectively (pre-PhD). Lastly, I will be highly obliged to you for allowing me to work with your organization. Thank you very much! Sincerely, Anup

Dr. Anup Kumar Patel

Indian Institute of Technology Kanpur India & Beckman Research Institute of Coh, CA, United States

Research Expertise

Biomaterials

Tissue Engineering

Polymer Composites

Drug Delivery

Nanotechnology

About

Publications

Tribological performance of laser peened Ti–6Al–4V

Wear / Jan 01, 2015

Kumar, D., Nadeem Akhtar, S., Kumar Patel, A., Ramkumar, J., & Balani, K. (2015). Tribological performance of laser peened Ti–6Al–4V. Wear, 322–323, 203–217. https://doi.org/10.1016/j.wear.2014.11.016

Processing, Characterization and Fretting Wear of Zinc Oxide and Silver Nanoparticles Reinforced Ultra High Molecular Weight Polyethylene Biopolymer Nanocomposite

JOM / Mar 17, 2015

Alam, F., Kumar, A., Patel, A. K., Sharma, R. K., & Balani, K. (2015). Processing, Characterization and Fretting Wear of Zinc Oxide and Silver Nanoparticles Reinforced Ultra High Molecular Weight Polyethylene Biopolymer Nanocomposite. JOM, 67(4), 688–701. https://doi.org/10.1007/s11837-015-1358-z

Domination of volumetric toughening by silver nanoparticles over interfacial strengthening of carbon nanotubes in bactericidal hydroxyapatite biocomposite

Materials Science and Engineering: C / Jan 01, 2014

Herkendell, K., Shukla, V. R., Patel, A. K., & Balani, K. (2014). Domination of volumetric toughening by silver nanoparticles over interfacial strengthening of carbon nanotubes in bactericidal hydroxyapatite biocomposite. Materials Science and Engineering: C, 34, 455–467. https://doi.org/10.1016/j.msec.2013.09.034

Enhanced Tribological and Bacterial Resistance of Carbon Nanotube with Ceria- and Silver-Incorporated Hydroxyapatite Biocoating

Nanomaterials / May 24, 2018

Pandey, A., Patel, A. K., S., A., Kumar, V., Sharma, R. K., Kanhed, S., Nigam, V. K., Keshri, A., Agarwal, A., & Balani, K. (2018). Enhanced Tribological and Bacterial Resistance of Carbon Nanotube with Ceria- and Silver-Incorporated Hydroxyapatite Biocoating. Nanomaterials, 8(6), 363. https://doi.org/10.3390/nano8060363

Applications of Biomaterials

Biosurfaces / Dec 12, 2014

Verma, S., Patel, A. K., Fatma, B., Rajesh, P. S. M., Singh, V., Verma, V., & Balani, K. (2014, December 12). Applications of Biomaterials. Biosurfaces; Wiley; Portico. https://doi.org/10.1002/9781118950623.ch10

Tissue Interaction with Biomaterials

Biosurfaces / Dec 12, 2014

Pandey, A., Patel, A. K., & Balani, K. (2014, December 12). Tissue Interaction with Biomaterials. Biosurfaces; Wiley; Portico. https://doi.org/10.1002/9781118950623.ch2

Functionalized Metallic Nanoparticles: Theranostic Applications

Multifunctional And Targeted Theranostic Nanomedicines / Jan 01, 2023

Patel, K. D., Patel, A. K., Sawadkar, P., Singh, B., & Perriman, A. W. (2023). Functionalized Metallic Nanoparticles: Theranostic Applications. In Multifunctional And Targeted Theranostic Nanomedicines (pp. 97–117). Springer Nature Singapore. https://doi.org/10.1007/978-981-99-0538-6_5

Tuning the properties of inorganic nanomaterials for theranostic applications in infectious diseases: Carbon nanotubes, quantum dots, graphene, and mesoporous carbon nanoparticles

Nanotheranostics for Treatment and Diagnosis of Infectious Diseases / Jan 01, 2022

Patel, K. D., Patel, A. K., Kurian, A. G., Singh, R. K., & Kim, H.-W. (2022). Tuning the properties of inorganic nanomaterials for theranostic applications in infectious diseases: Carbon nanotubes, quantum dots, graphene, and mesoporous carbon nanoparticles. In Nanotheranostics for Treatment and Diagnosis of Infectious Diseases (pp. 319–352). Elsevier. https://doi.org/10.1016/b978-0-323-91201-3.00011-6

Microporous Hydroxyapatite Ceramic Composites as Tissue Engineering Scaffolds: An Experimental and Computational Study

Advanced Engineering Materials / Mar 22, 2018

Kanhed, S., Awasthi, S., Midha, S., Nair, J., Nisar, A., Patel, A. K., Pandey, A., Sharma, R., Goel, S., Upadhyaya, A., Ghosh, S., & Balani, K. (2018). Microporous Hydroxyapatite Ceramic Composites as Tissue Engineering Scaffolds: An Experimental and Computational Study. Advanced Engineering Materials, 20(7). Portico. https://doi.org/10.1002/adem.201701062

Carbon Nanotube Functionalization Decreases Osteogenic Differentiation in Aluminum Oxide Reinforced Ultrahigh Molecular Weight Polyethylene

ACS Biomaterials Science & Engineering / Jul 19, 2016

Patel, A. K., Trivedi, P., & Balani, K. (2016). Carbon Nanotube Functionalization Decreases Osteogenic Differentiation in Aluminum Oxide Reinforced Ultrahigh Molecular Weight Polyethylene. ACS Biomaterials Science & Engineering, 2(8), 1242–1256. https://doi.org/10.1021/acsbiomaterials.6b00154

Cellular response ofEscherichia colito Mg-2Zn-2Gd alloy with different grain structure: mechanism of disruption of colonisation

Materials Technology / Nov 09, 2016

Trivedi, P., Nune, K. C., Misra, R. D. K., Patel, A. K., Balani, K., & Jayganthan, R. (2016). Cellular response ofEscherichia colito Mg-2Zn-2Gd alloy with different grain structure: mechanism of disruption of colonisation. Materials Technology, 31(13), 836–844. https://doi.org/10.1080/10667857.2016.1239798

Dispersion fraction enhances cellular growth of carbon nanotube and aluminum oxide reinforced ultrahigh molecular weight polyethylene biocomposites

Materials Science and Engineering: C / Jan 01, 2015

Patel, A. K., & Balani, K. (2015). Dispersion fraction enhances cellular growth of carbon nanotube and aluminum oxide reinforced ultrahigh molecular weight polyethylene biocomposites. Materials Science and Engineering: C, 46, 504–513. https://doi.org/10.1016/j.msec.2014.10.075

Nanomechanical Characterization and Protein Adsorption of Cold-Rolled Zirconium Alloy

JOM / Feb 12, 2015

Trivedi, P., Patel, A. K., Maurya, R., Jayaganthan, R., & Balani, K. (2015). Nanomechanical Characterization and Protein Adsorption of Cold-Rolled Zirconium Alloy. JOM, 67(4), 726–732. https://doi.org/10.1007/s11837-015-1324-9

Education

Indian Institute of Technology Kanpur

PhD, Materials Engg. / April, 2017

Kanpur

Experience

City of Hope Beckman Research Institute

Postdoc

Links & Social Media

Research Web Site

https://scholar.google.co.in/citations?user=4UtgzxwAAAAJ&hl=en

ORCID

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