Jenya Antonova

Independent Health Economist with deep expertise in PRO and COA, fusing a passion for winning strategies with a track record of award-winning research excellence

Research Expertise

Pharmaceutical Science
Health Policy
Pharmacy
Dermatology
Immunology and Allergy
Immunology
Pulmonary and Respiratory Medicine
Demography
Life-span and Life-course Studies
Gerontology
Public Health, Environmental and Occupational Health
Infectious Diseases
Molecular Medicine
Rheumatology
Orthopedics and Sports Medicine
Critical Care and Intensive Care Medicine
Emergency Medicine
Geriatrics and Gerontology
Oncology
Obstetrics and Gynecology

About

As an independent health economist, I am opening my schedule to new projects and partnerships. Contact me if you need expert support with patient-reported outcomes (PROs), clinical outcome assessment (COA), or health economics and outcomes research (HEOR). #OpenToWork   My clients hire me for my strategic acumen, organizational agility, holistic vision, and scientific excellence in project execution. Here's a snapshot of areas where I've had the privilege to make an impact:   **HEOR Strategic Acumen:** Tailored value propositions, access strategies, and evidence generation plans that resonate with payers, regulators, policymakers, healthcare providers, and patients.   **PRO & COA Strategic and Tactical Support**: Maximized the value of products through robust and comprehensive PRO and COA strategy for regulatory, HTA, and publication purposes; supported regulatory communications; demonstrated excellence in the execution of PRO and COA dossiers, statistical analysis plans, clinical study reports, and publications.   **Literature Reviews**: Executed targeted (quick and clean) and systematic literature reviews that deliver insights that drive strategy.   **In-House Support and Collaborative Leadership**: Provided strategic in-house tactical support and adeptly steered cross-functional collaboration within matrix organizations, leading to unified progress and shared victories.

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Publications

Patient Outcomes, Health Care Resource Use, and Costs Associated with High Versus Low HEDIS Asthma Medication Ratio
Journal of Managed Care & Specialty Pharmacy
2017
Baseline asthma burden, comorbidities, and biomarkers in omalizumab-treated patients in PROSPERO
Annals of Allergy, Asthma & Immunology
2017
Omalizumab response in patients with chronic idiopathic urticaria: Insights from the XTEND-CIU study
Journal of the American Academy of Dermatology
2018
Importance of angioedema-free days in patients with chronic idiopathic or spontaneous urticaria
Annals of Allergy, Asthma & Immunology
2017
Corticosteroid-related toxicity in patients with chronic idiopathic urticaria‐chronic spontaneous urticaria
Allergy and Asthma Proceedings
2016
Health care resource use and costs associated with possible side effects of high oral corticosteroid use in asthma: a claims-based analysis
ClinicoEconomics and Outcomes Research
2016
Improvement of sleep in patients with chronic idiopathic/spontaneous urticaria treated with omalizumab: results of three randomized, double-blind, placebo-controlled studies
Clinical and Translational Allergy
2016
Angioedema in the omalizumab chronic idiopathic/spontaneous urticaria pivotal studies
Annals of Allergy, Asthma & Immunology
2016
Timing and duration of omalizumab response in patients with chronic idiopathic/spontaneous urticaria
Journal of Allergy and Clinical Immunology
2016
Resource Use and Costs in an Insured Population of Patients with Chronic Idiopathic/Spontaneous Urticaria
American Journal of Clinical Dermatology
2015
Can Bundled Payment Improve Quality and Efficiency of Care for Patients with Hip Fractures?
Journal of Aging & Social Policy
2015
Seasonal influenza vaccination trends from 2007–2011 in privately insured children and adults in the United States
Vaccine
2014
Tibia shaft fractures: costly burden of nonunions
BMC Musculoskeletal Disorders
2013
Burden of paediatric influenza in Western Europe: a systematic review
BMC Public Health
2012
Older people presenting to the emergency department after a fall: a population with substantial recurrent healthcare use
Emergency Medicine Journal
2011
Scope and Severity Index: A Metric for Quantifying Nursing Home Survey Deficiency Number, Scope, and Severity Adjusted for the State-Related Measurement Bias
Journal of the American Medical Directors Association
2012
Omalizumab substantially improves dermatology‐related quality of life in patients with chronic spontaneous urticaria
Journal of the European Academy of Dermatology and Venereology
2017
An Updated Review of Food and Drug Administration Warning and Untitled Letters for Clinical Outcome Assessment Claims Between 2013 and 2021
Value in Health
2023
The Incidence, Prevalence, and Associated Costs of Anemia, Malignancy, Venous Thromboembolism, Major Adverse Cardiovascular Events, and Infections in Rheumatoid Arthritis Patients by Treatment History in the United States
ACR Open Rheumatology
2021
The Impact of Special Focus Facility Nursing Homes on Market Quality
The Gerontologist
2010
Efficacy of niraparib therapy in patients with newly diagnosed advanced ovarian cancer by BRCA and homologous recombination status: PRIMA/ENGOT-OV26/GOG-3012 study
Gynecologic Oncology
2020

Education

University of Wisconsin–Madison

Ph.D., Health system engineering / June, 2008

Madison, Wisconsin, United States of America

University of Wisconsin–Madison

M.S., Health Services Research / June, 2006

Madison, Wisconsin, United States of America

University of Wisconsin–Madison

M.S., Industrial and system engineering / June, 2005

Madison, Wisconsin, United States of America

Ural State University of Economics

B.S., Economics

Yekaterinburg

Experience

Compass Strategy and Research, Inc.

Principal Scientist / February, 2022Present

Was hired to maximize treatment value through patient-centered outcomes • Support executive team to enhance product value proposition through robust Value & Access strategy • Champion excellence in HEOR and PRO/COA strategy implementation through effective in-house project management and strategic oversight • Maximize the value propositions of medical products through the development of HEOR and PRO/COA strategy focused on multiple stakeholders (patients, caregivers, regulators, HTA and payer agencies, and policymakers) • Persuasively communicated the unique value of products to multiple stakeholders, securing their support and partnership • Enable excellence and compliance in the planning, execution, and publication of HEOR and PRO/COA research by optimizing scientific planning, oversight, and publication approval processes

Aqtual, Inc.

Head of Value & Access / January, 2023December, 2023

Was hired to build V&A capacity and shape the product value proposition • Addressed and resolved pivotal issues to refine business strategies and optimize decision-making in development programs • Crafted and articulated a compelling product value story, tailored to optimize value from the payer perspective • Formulated a robust Value & Access (V&A) strategy, concentrating on current and future indications to enhance market positioning • Established strategic relationships with key payer decision-makers, fostering avenues for impactful collaborations • Facilitated a standout market debut for a company emerging from stealth mode through strategic planning and execution of key publications • Established and maintained company-level standards of excellence and compliance in HEOR and PRO/COA research planning, execution, and publication, through streamlined scientific planning, meticulous oversight, and robust publication approval processes

Gilead Sciences, Inc.

Director, PRO and COA Center of Excellence / March, 2020February, 2022

Was hired to ensure excellence in COA strategy, execution, analyses, and publications • Enabled successful PRO discussions with regulatory agencies (FDA, EMA) by contributing to briefing documents and participating in meetings with the FDA • Drove excellence in patient-focused drug development by developing training on the value of PRO/COA for multiple stakeholders and best practices in PRO/COA strategy and research • Ensured success of critical (high-priority and high-visibility) projects by advising therapeutic-area HEOR colleagues on PRO strategy during launches, protocol design, COA analyses, and regulatory communications • Enabled excellence and compliance in the planning, execution, and publication of PRO/COA research by optimizing scientific planning, oversight, and publication approval processes • Maximized the value of Gilead products by optimizing PRO/COA for HTA and payer decisions

Director, Health Economics and Outcomes Research / September, 2017February, 2020

Was hired to create a comprehensive research agenda to demonstrate the value of a multi-indication product via real-world evidence and clinical outcome assessment • Led, developed, and executed HEOR strategy supporting a product launch • Communicated the value Gilead products by leading 25+ publications • Gilead Sciences (continued) • Enabled successful publications of PRO and COA in clinical trial result in oncology, inflammation, liver disease • Strengthened clinical programs by informing clinical trial design, statistical analysis plans, and best practices in PRO and COA methodology • Elevated Gilead recognition in the clinical and scientific communities by cultivating and managing relationships with clinical experts and key opinion leaders (KOLs)

Genentech, LLC

Senior Health Economist / February, 2014August, 2017

Was hired to lead HEOR activities (economic modeling, real-world evidence, COA research) for 2 sequential launches • Ensured close cross-functional integration of HEOR strategy through collaborative development and execution of HEOR strategic plans • Enabled two successful launches of two line-extensions through RWE, economic modeling, and PRO research • Enabled the successful assessment of PRO in Genentech Phase 4 and observational studies by developing PRO strategy and informing endpoint • Facilitated patient centricity in clinical practice by developing an iOS app (MyHivesDiary) to collect symptoms of chronic idiopathic urticaria (CIU) in daily life • Expanded the value of Xolair by developing publication strategy and leading 50+ peer-reviewed publications (receiving 4 publication awards)

MedImmune, Inc.

Senior Manager, Health Economics and Outcomes Research / March, 2011December, 2013

Was hired to support a product launch in the EU, set up and execute a comprehensive research agenda, and communicate the product value through publications • Ensured a successful launch of a MedImmune product by executing and publishing HEOR research (RWE, economic modeling, value dossier) • Advised expansion of value proposition in oncology by outlining the highest unmet need in patients through early-phase economic modeling • Informed national and local policies on pediatric vaccination in the US and UK through economic models demonstrating that vaccination of school-age children protects the elderly from influenza morbidity and mortality

Eli Lilly and Company, Inc.

Research Scientist / July, 2008February, 2011

Was hired to support a portfolio of multiple indications to ensure comprehensive value proposition, HEOR strategy • Supported a successful launch of an acquired (short-notice) product through the leadership developing PRO strategy and executing qualitative research to support the PRO instrument design • Ensured breadth and strength of treatment value by leading cross-functional work on the development of value-proposition documents for products in men’s health and musculoskeletal health • Supported the expansion of the treatment value proposition by developing PRO strategy for clinical trials • Maximized the value of treatments by advising clinical trial design and instrument development; represented PRO expertise at the FDA meetings

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