Dr. Raja Mukherjee, Ph.D.

Senior Research Scientist at TCGLIFESCIENCES

Research Expertise

Organic synthesis
Chemical Biology
Synthetic Biology
Catalysis
Biochemistry
Organic Chemistry
Drug Discovery
Colloid and Surface Chemistry
Electrical and Electronic Engineering
Ecology, Evolution, Behavior and Systematics
Physical and Theoretical Chemistry

About

Dr. Raja Mukherjee is a highly accomplished chemist with a strong research background in organic chemistry. He completed his PhD in Chemistry from Indian Institute of Technology Kharagpur in 2014, where his research focused on the development of new methods for the synthesis of natural products. Following his PhD, he worked as a Post Doctoral Research Fellow at University of Alberta and Boston College, where he gained extensive experience in the field of synthetic organic chemistry and chemical biology. Currently, Dr. Mukherjee is working as a Senior Research Scientist at TCGLIFESCIENCES, a leading pharmaceutical company. In this role, he leads a team of scientists and oversees projects related to drug discovery and development. He has published numerous research papers in top peer-reviewed journals and has presented his work at international conferences. Dr. Mukherjee's expertise lies in the design and synthesis of novel molecules with medicinal properties. He has a deep understanding of various analytical techniques and has experience in using them to characterize and elucidate the structure of complex molecules. Apart from his research work, Dr. Mukherjee is also passionate about mentoring young scientists and has supervised several graduate and undergraduate students. Overall, Dr. Raja Mukherjee is a dedicated and highly skilled chemist with a proven track record of success in the field of organic chemistry. His passion for research and his commitment to making a positive impact in the world through his work make him a valuable asset to any organization.

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Publications

A Precise Chemical Strategy To Alter the Receptor Specificity of the Adeno‐Associated Virus
Angewandte Chemie International Edition
2016
Defining the current scope and limitations of dual noncanonical amino acid mutagenesis in mammalian cells
Chemical Science
2017
Expanding the Scope of Single- and Double-Noncanonical Amino Acid Mutagenesis in Mammalian Cells Using Orthogonal Polyspecific Leucyl-tRNA Synthetases
Biochemistry
2017
Structure and synthesis of nudiflorine
Tetrahedron
1966
Precise Photoremovable Perturbation of a Virus–Host Interaction
Angewandte Chemie
2017
Genetically Encoded Fragment-Based Discovery from Phage-Displayed Macrocyclic Libraries with Genetically Encoded Unnatural Pharmacophores
Journal of the American Chemical Society
2021
Garratt–Braverman Cyclization, a Powerful Tool for C–C Bond Formation
Synlett
2012
Selectivity in Garratt–Braverman Cyclization of Aryl-/Heteroaryl-Substituted Unsymmetrical Bis-Propargyl Systems: Formal Synthesis of 7′-Desmethylkealiiquinone
The Journal of Organic Chemistry
2014
Reactivity of Bispropargyl Sulfones under Basic Conditions: Interplay Between Garratt–Braverman and Schmittel/Myers–Saito Cyclization Pathway
Chemistry – An Asian Journal
2012
Genetically-encoded discovery of proteolytically stable bicyclic inhibitors for morphogen NODAL
Chemical Science
2021
A self-organizing fuzzy inference system for electric field optimization of HV electrode systems
IEEE Transactions on Dielectrics and Electrical Insulation
2001
Synthesis of 1-Indol-3-yl-carbazoles via Garratt-Braverman Cyclization
Synlett
2012
The chemistry of securinine, an alkaloid of the root of securinega suffruticosa (Pall.) rehd
Die Naturwissenschaften
1963
Genetically Encoded Fragment-Based Discovery (GE-FBD) from Phage-Displayed Macrocyclic Libraries with Genetically-Encoded Unnatural Pharmacophores
Unknown Venue
2020
Tandem Wittig/Diels–Alder diversification of genetically encoded peptide libraries
Organic & Biomolecular Chemistry
2017
Production and Chemoselective Modification of Adeno-Associated Virus Site-Specifically Incorporating an Unnatural Amino Acid Residue into Its Capsid
Methods in Molecular Biology
2018
Development of an ‘Automated’ Cad Model Generation of Globally Optimized Container Ship Design
Design & Operation of Container Ships 2014
2014
Genetically-Encoded Discovery of Proteolytically Stable Bicyclic Inhibitors of Morphogen NODAL
Unknown Venue
2021
Precise Photoremovable Perturbation of a Virus–Host Interaction
Angewandte Chemie International Edition
2017
Sodium sulfide in methanol: a two-in-one reagent for deprotection of silyl and formation of propargyl sulfide
Tetrahedron Letters
2015

Education

Indian Institute of Technology Kharagpur

PhD, Chemistry / July, 2014

Kharagpur

Indian Institute of Technology (Indian School of Mines), Dhanbad

MSc, Chemistry / June, 2008

Dhanbad

University of Burdwan

BSc, Chemistry / May, 2006

Bardhaman

Experience

TCGLIFESCIENCES

Senior Research Scientist / September, 2019Present

University of Alberta

Post Doctoral Research Fellow / November, 2016July, 2019

Boston College

Post Doctoral Research Fellow / July, 2014December, 2015

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