Work with Andrew Horne | NotedSource
Andrew Horne is a senior academic clinician–researcher in
reproductive health based at the University of Edinburgh,
leading the Centre for Reproductive Health while
maintaining an active clinical practice. He specialises in
endometriosis and clinical trial design, with a strong
track record in grant funding, >250 peer-reviewed
publications and international collaboration. He directs
multidisciplinary research teams, supervises PhD students
and contributes to national and international research
assessments and funding panels.
https://cv.notedsource.io/me/DZLOPWWR
Andrew Horne
Clinical expert in endometriosis and pelvic pain
About
Andrew Horne is a senior academic
clinician–researcher in reproductive health
based at the University of Edinburgh, leading
the Centre for Reproductive Health while
maintaining an active clinical practice. He
specialises in endometriosis and clinical
trial design, with a strong track record in
grant funding, >250 peer-reviewed
publications and international collaboration.
He directs multidisciplinary research teams,
supervises PhD students and contributes to
national and international research
assessments and funding panels.
Publications
Anti-Müllerian hormone decreased in women
with superficial peritoneal endometriosis
and associated with an elevated
inflammatory profile
Reproduction and Fertility
2026
ESPriT1: the effectiveness of laparoscopic
treatment of isolated superficial
peritoneal endometriosis for managing
chronic pelvic pain in women: a randomised
controlled feasibility trial
Reproduction and Fertility
2026
Effectiveness of an anti-inflammatory diet
intervention and cognitive behavioural
therapy in endometriosis: protocol for a
randomised controlled clinical trial
BMJ Open
2026
Risk factors and prediction models for
pain after endometriosis-related
surgery—what do we (not) know yet
Pain
2026
Building Bridges: Enhancing Diagnosis and
Care for Endometriosis Across the
Primary-Secondary Care Continuum
Women's Reproductive Health
2025
Author Reply
BJOG: An International Journal of
Obstetrics & Gynaecology
2025
Linzagolix, with and without add-back
therapy, in women with
endometriosis-associated pain: results
from EDELWEISS 6, a double-blind
randomized extension and withdrawal study
Human Reproduction Open
2026
Endometriosis: new insights and
opportunities for relief of symptoms
Biology of Reproduction
2025
Developing the
FIGO
‐
IPPS
“R U
MOVVING SOMe
” classification system for female chronic
pelvic pain
International Journal of Gynecology
& Obstetrics
2025
Current Pathways of Care Continue to Fail
Those With a Diagnosis of Endometriosis
BJOG: An International Journal of
Obstetrics & Gynaecology
2025
Anti-Müllerian hormone is decreased in
women with superficial peritoneal
endometriosis and associated with an
elevated inflammatory profile
Unknown Venue
2025
Predicting pain reduction following
laparoscopic surgery for endometriosis: a
retrospective cohort study using UK
national and research databases
BMJ Open
2025
Perceived effectiveness of endometriosis
therapies on fatigue: an international
survey
Reproduction and Fertility
2025
Consensus on Symptom Selection for
Endometriosis Questionnaires: A Modified
e‐Delphi Study
BJOG: An International Journal of
Obstetrics & Gynaecology
2025
Exploring pre-diagnosis hospital contacts
in women with endometriosis using ICD-10:
a Danish case–control study
Human Reproduction
2024
Dynamic roles of ILC3 in endometrial
repair and regeneration
Discovery Immunology
2025
Symptom flares in women with chronic
pelvic pain: Questionnaire study within a
cohort study (translational research in
pelvic pain (
TRiPP
))
BJOG: An International Journal of
Obstetrics & Gynaecology
2024
Single-cell analysis identifies distinct
macrophage phenotypes associated with
prodisease and proresolving functions in
the endometriotic niche
Proceedings of the National Academy of
Sciences
2024
Endometriosis: recent advances that could
accelerate diagnosis and improve care
Trends in Molecular Medicine
2024
Genome-wide association reveals a locus in
neuregulin 3 associated with gabapentin
efficacy in women with chronic pelvic pain
iScience
2024
Symptom flares: a clinically important but
under-explored challenge for women with
chronic pelvic pain
Unknown Venue
2024
Linzagolix therapy versus a placebo in
patients with endometriosis-associated
pain: a prospective, randomized,
double-blind, Phase 3 study (EDELWEISS 3)
Human Reproduction
2024
Long acting progestogens versus combined
oral contraceptive pill for preventing
recurrence of endometriosis related pain:
the PRE-EMPT pragmatic, parallel group,
open label, randomised controlled trial
BMJ
2024
Microbiome: The impact of the
microbiota–gut–brain axis on
endometriosis-associated symptoms:
mechanisms and opportunities for
personalised management strategies
Reproduction and Fertility
2024
Endometriosis: time to think differently
(and together)
British Journal of General
Practice
2024
Endometriosis among African Women
Unknown Venue
2024
Time for global health policy and research
leaders to prioritize endometriosis
Nature Communications
2023
Oral vinorelbine to treat women with
ectopic pregnancy: a phase 1 clinical
safety and tolerability study
Fertility and Sterility
2023
Global endometrial DNA methylation
analysis reveals insights into mQTL
regulation and associated endometriosis
disease risk and endometrial function
Communications Biology
2023
Early (Days 1–4) post-treatment serum hCG
level changes predict single-dose
methotrexate treatment success in tubal
ectopic pregnancy
Human Reproduction
2023
Subsequent pregnancy outcomes among women
with tubal ectopic pregnancy treated with
methotrexate
Reproduction and Fertility
2023
Comparing inpatient management of chronic
pelvic pain flares before and after the
COVID-19 pandemic
Reproduction and Fertility
2023
Gefitinib and methotrexate to resolve
tubal ectopic pregnancy: the GEM3 RCT
Efficacy and Mechanism Evaluation
2023
Combination of gefitinib and methotrexate
to treat tubal ectopic pregnancy (GEM3): a
multicentre, randomised, double-blind,
placebo-controlled trial
The Lancet
2023
Pathophysiology, diagnosis, and management
of endometriosis
BMJ
2022
Endometriosis among African women
Reproduction and Fertility
2022
Impact of endometriosis on women’s life
decisions and goal attainment: a
cross-sectional survey of members of an
online patient community
BMJ Open
2022
ESHRE guideline: endometriosis
Human Reproduction Open
2022
Endometriosis classification systems: an
international survey to map current
knowledge and uptake
Human Reproduction Open
2022
Dichloroacetate as a possible treatment
for endometriosis-associated pain: a
single-arm open-label exploratory clinical
trial (EPiC)
Pilot and Feasibility Studies
2021
Lay awareness of USS to diagnose
endometriosis remains low
BJOG: An International Journal of
Obstetrics & Gynaecology
2021
An international terminology for
endometriosis, 2021,
Human Reproduction Open
2021
Endometriosis classification, staging and
reporting systems: a review on the road to
a universally accepted endometriosis
classification,
Human Reproduction Open
2021
Is There a Hidden Burden of Disease as a
Result of Epigenetic
Epithelial-to-Mesenchymal Transition
Following
Chlamydia trachomatis Genital Tract
Infection?
The Journal of Infectious
Diseases
2021
Bioluminescent imaging in induced mouse
models of endometriosis reveals
differences in four model variations
Disease Models & Mechanisms
2021
Letter to the Editor: Endometriosis and
malignancy—The intriguing relationship
International Journal of Gynecology
& Obstetrics
2021
Endometriosis: Etiology, pathobiology, and
therapeutic prospects
Cell
2021
Development and Validation of Clinical
Prediction Models for Surgical Success in
Patients With Endometriosis: Protocol for
a Mixed Methods Study
JMIR Research Protocols
2021
Macrophages inhibit and enhance
endometriosis depending on their origin
Proceedings of the National Academy of
Sciences
2021
An ultrasound study of the prevalence of
endometriosis in women attending for early
pregnancy assessment: a prospective
observational study
Unknown Venue
2020
Gabapentin to reduce pain in women aged
between 18 and 50 years with chronic
pelvic pain: the GaPP2 RCT
Efficacy and Mechanism Evaluation
2020
Important concepts to consider in
endometriosis surgical trials
BJOG: An International Journal of
Obstetrics & Gynaecology
2020
Gabapentin for chronic pelvic pain in
women (GaPP2): a multicentre, randomised,
double-blind, placebo-controlled trial
The Lancet
2020
Re: Effect of progestogen for women with
threatened miscarriage: a systematic
review and meta‐analysis
BJOG: An International Journal of
Obstetrics & Gynaecology
2020
Mifepristone and misoprostol versus
misoprostol alone for the management of
missed miscarriage (MifeMiso): a
randomised, double-blind,
placebo-controlled trial
The Lancet
2020
Development and Validation of Clinical
Prediction Models for Surgical Success in
Patients With Endometriosis: Protocol for
a Mixed Methods Study (Preprint)
Unknown Venue
2020
Re: Effect of progestogen for women with
threatened miscarriage: a systematic
review and meta‐analysis. (First comment
on BJOG-19-1550.R1)
Unknown Venue
2020
Endometriosis clinical guidance during the
COVID-19 pandemic
Unknown Venue
2020
Self-management strategies to consider to
combat endometriosis symptoms during the
COVID-19 pandemic
Human Reproduction Open
2020
A two-arm parallel double-blind randomised
controlled pilot trial of the efficacy of
Omega-3 polyunsaturated fatty acids for
the treatment of women with
endometriosis-associated pain (PurFECT1)
PLOS ONE
2020
Repurposing dichloroacetate for the
treatment of women with endometriosis
Proceedings of the National Academy of
Sciences
2019
Informing women with endometriosis about
ovarian cancer risk
The Lancet
2017
Top ten endometriosis research priorities
in the UK and Ireland
The Lancet
2017
Molecular diagnostics and therapeutics for
ectopic pregnancy
MHR: Basic science of reproductive
medicine
2014
World Endometriosis Research Foundation
Endometriosis Phenome and Biobanking
Harmonisation Project: I. Surgical
phenotype data collection in endometriosis
research
Fertility and Sterility
2014
World Endometriosis Research Foundation
Endometriosis Phenome and Biobanking
Harmonisation Project: IV. Tissue
collection, processing, and storage in
endometriosis research
Fertility and Sterility
2014
World Endometriosis Research Foundation
Endometriosis Phenome and biobanking
harmonization project: II. Clinical and
covariate phenotype data collection in
endometriosis research
Fertility and Sterility
2014
World Endometriosis Research Foundation
Endometriosis Phenome and Biobanking
Harmonization Project: III. Fluid
biospecimen collection, processing, and
storage in endometriosis research
Fertility and Sterility
2014
Estrogen Receptor (ER) Agonists
Differentially Regulate Neuroangiogenesis
in Peritoneal Endometriosis via the
Repellent Factor SLIT3
Endocrinology
2014
Elevated Peritoneal Expression and
Estrogen Regulation of Nociceptive Ion
Channels in Endometriosis
The Journal of Clinical Endocrinology
& Metabolism
2014
Transforming Growth Factor-β Induced
Warburg-Like Metabolic Reprogramming May
Underpin the Development of Peritoneal
Endometriosis
The Journal of Clinical Endocrinology
& Metabolism
2014
A Novel Mouse Model of Endometriosis
Mimics Human Phenotype and Reveals
Insights into the Inflammatory
Contribution of Shed Endometrium
The American Journal of Pathology
2014
Combination gefitinib and methotrexate
treatment for non-tubal ectopic
pregnancies: a case series
Human Reproduction
2014
Women's satisfaction and symptoms
following NovaSure endometrial ablation: A
postal questionnaire survey in Lothian,
Scotland
Journal of Obstetrics and
Gynaecology
2014
ESHRE guideline: management of women with
endometriosis
Human Reproduction
2014
Clinical performance of RNA and DNA based
HPV testing in a colposcopy setting:
Influence of assay target, cut off and age
Journal of Clinical Virology
2014
Quantitative Serial MRI of the Treated
Fibroid Uterus
PLoS ONE
2014
The Association between Smoking and
Ectopic Pregnancy: Why Nicotine Is BAD for
Your Fallopian Tube
PLoS ONE
2014
The Peritoneum Is Both a Source and Target
of TGF-β in Women with Endometriosis
PLoS ONE
2014
Characterization of the Temporal and
Spatial Expression of a Disintegrin and
Metalloprotease 17 in the Human
Endometrium and Fallopian Tube
Reproductive Sciences
2013
The role of leukemia inhibitory factor in
tubal ectopic pregnancy
Placenta
2013
Combination Gefitinib and Methotrexate
Compared With Methotrexate Alone to Treat
Ectopic Pregnancy
Obstetrics & Gynecology
2013
Effects of Gefitinib, an Epidermal Growth
Factor Receptor Inhibitor, on Human
Placental Cell Growth
Obstetrics & Gynecology
2013
The significant effect of endometriosis on
physical, mental and social wellbeing:
results from an international
cross-sectional survey
Human Reproduction
2013
The impact of endometriosis on quality of
life in Hungary
Orvosi Hetilap
2013
The financial costs to patients of
diagnosing and excluding ectopic pregnancy
Journal of Family Planning and
Reproductive Health Care
2012
Targeted Nanoparticle Delivery of
Doxorubicin Into Placental Tissues to
Treat Ectopic Pregnancies
Endocrinology
2013
Maternal Serum Macrophage Inhibitory
Cytokine-1 as a Biomarker for Ectopic
Pregnancy in Women with a Pregnancy of
Unknown Location
PLoS ONE
2013
Phase II single arm open label multicentre
clinical trial to evaluate the efficacy
and side effects of a combination of
gefitinib and methotrexate to treat tubal
ectopic pregnancies (GEM II): study
protocol
BMJ Open
2013
Shotgun Proteomics Identifies Serum
Fibronectin as a Candidate Diagnostic
Biomarker for Inclusion in Future
Multiplex Tests for Ectopic Pregnancy
PLoS ONE
2013
The impact of tubal ectopic pregnancy in
Papua New Guinea – a retrospective case
review
BMC Pregnancy and Childbirth
2013
The role of the peritoneum in the
pathogenesis of endometriosis
Human Reproduction Update
2013
Using a decline in serum hCG between days
0–4 to predict ectopic pregnancy treatment
success after single-dose methotrexate: a
retrospective cohort study
BMC Pregnancy and Childbirth
2013
Ectopic Pregnancy
Clinical Chemistry
2012
The paracrinology of tubal ectopic
pregnancy
Molecular and Cellular
Endocrinology
2012
The burden of endometriosis: costs and
quality of life of women with
endometriosis and treated in referral
centres
Human Reproduction
2012
A new age has come: the redefinition of
women's health care
Journal of Family Planning and
Reproductive Health Care
2012
Human Fallopian tube epithelium
constitutively expresses integrin
endometrial receptivity markers: no
evidence for a tubal implantation window
Molecular Human Reproduction
2011
Wnt activation downregulates
olfactomedin-1 in Fallopian tubal
epithelial cells: a microenvironment
predisposed to tubal ectopic pregnancy
Laboratory Investigation
2012
Pregnancy of unknown viability or
location: less is more in the majority of
cases
Journal of Family Planning and
Reproductive Health Care
2011
Evaluation of ADAM-12 as a Diagnostic
Biomarker of Ectopic Pregnancy in Women
with a Pregnancy of Unknown Location
PLoS ONE
2012
GaPP: a pilot randomised controlled trial
of the efficacy of action of gabapentin
for the management of chronic pelvic pain
in women: study protocol: Figure 1
BMJ Open
2012
Has increased clinical experience with
methotrexate reduced the direct costs of
medical management of ectopic pregnancy
compared to surgery?
BMC Pregnancy and Childbirth
2012
Mechanisms of disease: the endocrinology
of ectopic pregnancy
Expert Reviews in Molecular
Medicine
2012
Ruptured heterotopic pregnancy: an unusual
presentation of an uncommon clinical
problem
BMJ Case Reports
2012
Surgical treatment of fibroids for
subfertility
Cochrane Database of Systematic
Reviews
2012
Diagnosis and management of ectopic
pregnancy
Journal of Family Planning and
Reproductive Health Care
2011
Laboratory models for studying ectopic
pregnancy
Current Opinion in Obstetrics &
Gynecology
2011
Normally rising hCG does not predict live
birth in women presenting with pain and
bleeding in early pregnancy
European Journal of Obstetrics &
Gynecology and Reproductive
Biology
2011
Lymphoid and myeloid cell populations in
the non-pregnant human Fallopian tube and
in ectopic pregnancy
Journal of Reproductive
Immunology
2011
Attenuated Tubal and Endometrial Urocortin
1 and Corticotropin-Releasing Hormone
Receptor Expression in Ectopic Pregnancy
Reproductive Sciences
2011
Immunity and vaccines against sexually
transmitted Chlamydia trachomatis
infection
Current Opinion in Infectious
Diseases
2011
Chlamydia trachomatis Infection Increases
Fallopian Tube PROKR2 via TLR2 and NFκB
Activation Resulting in a Microenvironment
Predisposed to Ectopic Pregnancy
The American Journal of Pathology
2011
Placental Growth Factor: A Promising
Diagnostic Biomarker for Tubal Ectopic
Pregnancy
The Journal of Clinical Endocrinology
& Metabolism
2011
Ectopic Pregnancy as a Model to Identify
Endometrial Genes and Signaling Pathways
Important in Decidualization and Regulated
by Local Trophoblast
PLoS ONE
2011
Endometriosis Cost Assessment (the
EndoCost Study): A Cost-of-Illness Study
Protocol
Gynecologic and Obstetric
Investigation
2010
Expression of the repulsive SLIT/ROBO
pathway in the human endometrium and
Fallopian tube
Molecular Human Reproduction
2010
Cotinine Exposure Increases Fallopian Tube
PROKR1 Expression via Nicotinic AChRα-7
The American Journal of Pathology
2010
Evidence of prokineticin dysregulation in
fallopian tube from women with ectopic
pregnancy
Fertility and Sterility
2010
Impact ofChlamydia trachomatisin
the reproductive setting: British
Fertility Society Guidelines for practice
Human Fertility
2010
The need for serum biomarker development
for diagnosing and excluding tubal ectopic
pregnancy
Acta Obstetricia et Gynecologica
Scandinavica
2010
Economic evaluation of diagnosing and
excluding ectopic pregnancy
Human Reproduction
2009
Current knowledge of the aetiology of
human tubal ectopic pregnancy
Human Reproduction Update
2010
Attenuated Sex Steroid Receptor Expression
in Fallopian Tube of Women with Ectopic
Pregnancy
The Journal of Clinical Endocrinology
& Metabolism
2009
Serum biomarkers of tubal ectopic
pregnancy: current candidates and future
possibilities
Reproduction
2009
Differential expression and regulation of
nuclear oligomerization domain proteins
NOD1 and NOD2 in human endometrium: a
potential role in innate immune protection
and menstruation
Molecular Human Reproduction
2009
Endometrial cysteine-rich secretory
protein 3 is inhibited by human chorionic
gonadotrophin, and is increased in the
decidua of tubal ectopic pregnancy
Molecular Human Reproduction
2009
Expression of secretory leukocyte protease
inhibitor and elafin in human fallopian
tube and in an in-vitro model of Chlamydia
trachomatis infection
Human Reproduction
2008
Altered secretory leukocyte protease
inhibitor expression in the uterine
decidua of tubal compared with
intrauterine pregnancy
Human Reproduction
2008
Endometrial Inhibin/Activin β-B Subunit
Expression Is Related to Decidualization
and Is Reduced in Tubal Ectopic Pregnancy
The Journal of Clinical Endocrinology
& Metabolism
2008
Innate immunity and disorders of the
female reproductive tract
REPRODUCTION
2008
Management of vascular uterine lesions
associated with persistent low-level human
chorionic gonadotrophin
Journal of Family Planning and
Reproductive Health Care
2008
CB1 Expression Is Attenuated in Fallopian
Tube and Decidua of Women with Ectopic
Pregnancy
PLoS ONE
2008
The Effect of Uterine Fibroids on Embryo
Implantation
Seminars in Reproductive Medicine
2007
Are portable bladder scanning and
real-time ultrasound accurate measures of
bladder volume in postnatal women?
Journal of Obstetrics and
Gynaecology
2007
The dilemma of future family planning and
the role of female fertility tests
Journal of Family Planning and
Reproductive Health Care
2006
Ovarian choriocarcinoma masquerading as
ectopic pregnancy
Journal of Obstetrics and
Gynaecology
2006
The effects of sex steroid hormones and
interleukin-1-beta on MUC1 expression in
endometrial epithelial cell lines
Reproduction
2006
Uterine torsion with placental abruption
Journal of Obstetrics and
Gynaecology
2006
The expression pattern of MUC1 glycoforms
and other biomarkers of endometrial
receptivity in fertile and infertile women
Molecular Reproduction and
Development
2005
Recurrent miscarriage
Journal of Family Planning and
Reproductive Health Care
2005
Adhesion molecules and the normal
endometrium
BJOG: An International Journal of
Obstetrics & Gynaecology
2002
Analysis of Epitopes on Endometrial
Epithelium by Scanning Immunoelectron
Microscopy
Biochemical and Biophysical Research
Communications
2002
MUC 1: a genetic susceptibility to
infertility?
The Lancet
2001
The endometrium and embryo implantation
BMJ
2000
Experience
University of Edinburgh
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