Enrico Capobianco

Expertise in network science and special interest in cancer domain. Scientific Leader, Advisor. Quant, Computational & Digital Biomedical & Health research.

Research Expertise

Networks
Machine Learning
Big Data
Systems Biology & Medicine
Statistics
Molecular Biology
Molecular Medicine
Immunology
Computer Science Applications
Statistics and Probability
Cancer Research
Oncology
Condensed Matter Physics
Statistics, Probability and Uncertainty
Applied Mathematics
Computational Mathematics
Control and Optimization
Management Science and Operations Research
Computer Networks and Communications
Genetics
Biophysics
Biotechnology
Computational Theory and Mathematics
Neurology
Cell Biology
Management of Technology and Innovation
Modeling and Simulation
Health Informatics
Control and Systems Engineering
Epidemiology
Artificial Intelligence
Numerical Analysis
Drug Discovery
Statistical and Nonlinear Physics
Cellular and Molecular Neuroscience

About

Enrico Capobianco is a highly experienced and accomplished expert in the fields of artificial intelligence, machine learning, and statistical learning. He holds a Post-doctoral Fellowship in AI, Machine & Statistical Learning, Neural Networks from Stanford University, which he completed in 1998. Prior to that, he received his PhD in Statistical Sciences from the University of Padua in 1995. With over 25 years of experience, Capobianco has held various positions in academia, research, and industry. Most recently, he served as the Associate Director of Computational Systems at The Jackson Laboratory, a leading non-profit research institute focused on genetics and genomics. In this role, he oversaw the development and implementation of computational systems and tools for genetic and genomic research. Throughout his career, Capobianco has published numerous articles and book chapters on topics such as machine learning, artificial intelligence, and computational biology. He has also been a keynote speaker at various international conferences and has received numerous awards and grants for his research. In addition to his professional achievements, Capobianco is known for his collaborative and innovative approach to problem-solving. He is constantly seeking new ways to apply advanced computational techniques to solve complex problems in various industries, from healthcare to finance. Overall, Enrico Capobianco is a highly respected and sought-after expert in the fields of AI, machine learning, and statistical learning. His education and experience have equipped him with the knowledge and skills to make significant contributions to the advancement of these fields.

Publications

Protein networking: insights into global functional organization of proteomes
PROTEOMICS
2008
Comorbidity: a multidimensional approach
Trends in Molecular Medicine
2013
Distinct Transcriptomic Features are Associated with Transitional and Mature B-Cell Populations in the Mouse Spleen
Frontiers in Immunology
2015
Separate and Combined Effects of DNMT and HDAC Inhibitors in Treating Human Multi-Drug Resistant Osteosarcoma HosDXR150 Cell Line
PLoS ONE
2014
Smart Cities, Big Data, and Communities: Reasoning From the Viewpoint of Attractors
IEEE Access
2016
Multiscale Analysis of Stock Index Return Volatility
Computational Economics
2004
Systems and precision medicine approaches to diabetes heterogeneity: a Big Data perspective
Clinical and Translational Medicine
2017
The landscape of BRAF transcript and protein variants in human cancer
Molecular Cancer
2017
Hammerstein system represention of financial volatility processes
The European Physical Journal B - Condensed Matter
2002
Smart cities and urban networks: are smart networks what we need?
Journal of Management Analytics
2015
WAVELET TRANSFORMS FOR THE STATISTICAL ANALYSIS OF RETURNS GENERATING STOCHASTIC PROCESSES
International Journal of Theoretical and Applied Finance
2001
Comorbidity networks: beyond disease correlations
Journal of Complex Networks
2015
RNA-Seq Data: A Complexity Journey
Computational and Structural Biotechnology Journal
2014
Ten Challenges for Systems Medicine
Frontiers in Genetics
2012
Multiresolution approximation for volatility processes
Quantitative Finance
2002
Independent Multiresolution Component Analysis and Matching Pursuit
Computational Statistics & Data Analysis
2003
From Medical Imaging to Radiomics: Role of Data Science for Advancing Precision Health
Journal of Personalized Medicine
2020
Exploring domains, clinical implications and environmental associations of a deep learning marker of biological ageing
Unknown Venue
2021
Integrative analysis of cancer imaging readouts by networks
Molecular Oncology
2014
Sub-Modular Resolution Analysis by Network Mixture Models
Statistical Applications in Genetics and Molecular Biology
2010
Multitype Network-Guided Target Controllability in Phenotypically Characterized Osteosarcoma: Role of Tumor Microenvironment
Frontiers in Immunology
2017
Data-driven clinical decision processes: it’s time
Journal of Translational Medicine
2019
Identification of potential therapeutic targets in a model of neuropathic pain
Frontiers in Genetics
2014
Semi-Parametric Estimation in Magnetic Resonance Spectroscopy: Automation of the Disentanglement Procedure
2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
2007
Empirical volatility analysis: feature detection and signal extraction with function dictionaries
Physica A: Statistical Mechanics and its Applications
2003
Emerging Putative Associations between Non-Coding RNAs and Protein-Coding Genes in Neuropathic Pain: Added Value from Reusing Microarray Data
Frontiers in Neurology
2016
Identification of BRAF 3′UTR Isoforms in Melanoma
Journal of Investigative Dermatology
2015
State-space stochastic volatility models: A review of estimation algorithms
Applied Stochastic Models and Data Analysis
1996
Vitamin D Modulation of Mitochondrial Oxidative Metabolism and mTOR Enforces Stress Adaptations and Anticancer Responses
JBMR Plus
2021
Ensemble inference by integrative cancer networks
Frontiers in Genetics
2014
Multiscale stochastic dynamics in finance
Physica A: Statistical Mechanics and its Applications
2004
Targeting Cancer with Epi-Drugs: A Precision Medicine Perspective
Current Pharmaceutical Biotechnology
2016
On Digital Therapeutics
Frontiers in Digital Humanities
2015
Pathway landscapes and epigenetic regulation in breast cancer and melanoma cell lines
Theoretical Biology and Medical Modelling
2014
In vivo quantitation of metabolites with an incomplete model function
Measurement Science and Technology
2009
Empowering Spot Detection in 2DE Images by Wavelet Denoising
In Silico Biology
2009
Kernel methods and flexible inference for complex stochastic dynamics
Physica A: Statistical Mechanics and its Applications
2008
Time-domain semi-parametric estimation based on a metabolite basis set
NMR in Biomedicine
2005
Wavelets
Statistical Modeling by Wavelets
1999
Role of Complex Networks for Integrating Medical Images and Radiomic Features of Intracranial Ependymoma Patients in Response to Proton Radiotherapy
Frontiers in Medicine
2020
Dynamic Networks in Systems Medicine
Frontiers in Genetics
2012
Expected Impacts of Connected Multimodal Imaging in Precision Oncology
Frontiers in Pharmacology
2016
Methods to Detect Transcribed Pseudogenes: RNA-Seq Discovery Allows Learning Through Features
Methods in Molecular Biology
2014
Model validation for gene selection and regulation maps
Functional & Integrative Genomics
2007
MINING TIME-DEPENDENT GENE FEATURES
Journal of Bioinformatics and Computational Biology
2005
Inferring modules from human protein interactome classes
BMC Systems Biology
2010
Next Generation Networks: Featuring the Potential Role of Emerging Applications in Translational Oncology
Journal of Clinical Medicine
2019
General Practitioners Records Are Epidemiological Predictors of Comorbidities: An Analytical Cross-Sectional 10-Year Retrospective Study
Journal of Clinical Medicine
2018
Epigenetically driven network cooperativity: meta-analysis in multi-drug resistant osteosarcoma
Journal of Complex Networks
2015
Inflammation blood and tissue factors of plaque growth in an experimental model evidenced by a systems approach
Frontiers in Genetics
2014
Neural networks and statistical inference: seeking robust and efficient learning
Computational Statistics & Data Analysis
2000
Time-course gene profiling and networks in demethylated retinoblastoma cell line
Oncotarget
2015
Manifold Learning in Protein Interactomes
Journal of Computational Biology
2011
Lineshape estimation in in vivo MR Spectroscopy without using a reference signal
2008 IEEE International Workshop on Imaging Systems and Techniques
2008
FUNCTIONAL APPROXIMATION IN MULTISCALE COMPLEX SYSTEMS
Advances in Complex Systems
2003
Editorial: Artificial Intelligence for Precision Medicine
Frontiers in Artificial Intelligence
2022
RNA-seq analysis reveals significant transcriptome changes in huntingtin-null human neuroblastoma cells
BMC Medical Genomics
2021
Use of instrumental variables in electronic health record-driven models
Statistical Methods in Medical Research
2016
Precision Oncology: The Promise of Big Data and the Legacy of Small Data
Frontiers in ICT
2017
Entropy embedding and fluctuation analysis in genomic manifolds
Communications in Nonlinear Science and Numerical Simulation
2009
Independent component analysis and resolution pursuit with wavelet and cosine packets
Neurocomputing
2002
A unifying view of stochastic approximation, Kalman filter and backpropagation
Proceedings of 1995 IEEE Workshop on Neural Networks for Signal Processing
Radiomics at a Glance: A Few Lessons Learned from Learning Approaches
Cancers
2020
Editorial: Trends in Digital Medicine
Frontiers in Medicine
2020
Imprecise Data and Their Impact on Translational Research in Medicine
Frontiers in Medicine
2020
Significant EHR Feature-Driven T2D Inference: Predictive Machine Learning and Networks
Frontiers in Big Data
2019
Immuno-Oncology Integrative Networks: Elucidating the Influences of Osteosarcoma Phenotypes
Cancer Informatics
2017
Prognostic models in coronary artery disease: Cox and network approaches
Royal Society Open Science
2015
Advances in translational biomedicine from systems approaches
Frontiers in Genetics
2017
Warehousing re-annotated cancer genes for biomarker meta-analysis
Computer Methods and Programs in Biomedicine
2013
Multiscale Characterization of Signaling Network Dynamics through Features
Statistical Applications in Genetics and Molecular Biology
2011
On network entropy and bio-interactome applications
Journal of Computational Science
2011
Value of digital biomarkers in precision medicine: implications in cancer, autoimmune diseases, and COVID-19
Expert Review of Precision Medicine and Drug Development
2021
Inference From Complex Networks: Role of Symmetry and Applicability to Images
Frontiers in Applied Mathematics and Statistics
2020
Ensemble Modeling Approach Targeting Heterogeneous RNA-Seq data: Application to Melanoma Pseudogenes
Scientific Reports
2017
Editorial: Physiology in Extreme Conditions: Adaptations and Unexpected Reactions
Frontiers in Physiology
2017
Corrigendum: Distinct Transcriptomic Features Are Associated with Transitional and Mature B-Cell Populations in the Mouse Spleen
Frontiers in Immunology
2016
A proteomic study of microgravity cardiac effects: feature maps of label-free LC-MALDI data for differential expression analysis
Molecular BioSystems
2010
ALIASING IN GENE FEATURE DETECTION BY PROJECTIVE METHODS
Journal of Bioinformatics and Computational Biology
2009
Mining protein–protein interaction networks: denoising effects
Journal of Statistical Mechanics: Theory and Experiment
2009
Statistical Embedding in Complex Biosystems
Journal of Integrative Bioinformatics
2006
On support vector machines and sparse approximation for random processes
Neurocomputing
2004
Semiparametric Artificial Neural Networks
Mathematics of Neural Networks
1997
Multivariate probability density estimation by wavelet methods: Strong consistency and rates for stationary time series
Stochastic Processes and their Applications
1997
Overview of triple negative breast cancer prognostic signatures in the context of data science-driven clinico-genomics research
Annals of Translational Medicine
2022
Characterization of huntingtin interactomes and their dynamic responses in living cells by proximity proteomics
Journal of Neurochemistry
2022
PTS is activated by ATF4 and promotes lung adenocarcinoma development via the Wnt pathway
Translational Lung Cancer Research
2022
Impaired Restoration of Global Protein Synthesis Contributes to Increased Vulnerability to Acute ER Stress Recovery in Huntington’s Disease
Cellular and Molecular Neurobiology
2021
Network assessment of demethylation treatment in melanoma: Differential transcriptome-methylome and antigen profile signatures
PLOS ONE
2018
Protein networks tomography
Systems Biomedicine
2013
Advances in Human Protein Interactome Inference
Contributions to Statistics
2008
Independent Component Analysis
Analysis of Multivariate and High-Dimensional Data
2013
High-dimensional role of AI and machine learning in cancer research
British Journal of Cancer
2022

Education

Stanford University

Post-doctoral Fellowship, AI, Machine & Statistical Learning, Neural Networks / 1998

Stanford, California, United States of America

University of Padua

PhD, Statistical Sciences / 1995

Padova

Experience

The Jackson Laboratory

Associate Director, Computational Systems / 20182024

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