TANISHA SINGH
Research Scientist, University of Pittsburgh, School of Medicine
Research Expertise
About
Publications
Melatonin inhibits cytosolic mitochondrial DNA–induced neuroinflammatory signaling in accelerated aging and neurodegeneration
Journal of Clinical Investigation / May 11, 2020
Jauhari, A., Baranov, S. V., Suofu, Y., Kim, J., Singh, T., Yablonska, S., Li, F., Wang, X., Oberly, P., Minnigh, M. B., Poloyac, S. M., Carlisle, D. L., & Friedlander, R. M. (2020). Melatonin inhibits cytosolic mitochondrial DNA–induced neuroinflammatory signaling in accelerated aging and neurodegeneration. Journal of Clinical Investigation, 130(6), 3124–3136. https://doi.org/10.1172/jci135026
Critical role of the miR‐200 family in regulating differentiation and proliferation of neurons
Journal of Neurochemistry / Apr 21, 2015
Pandey, A., Singh, P., Jauhari, A., Singh, T., Khan, F., Pant, A. B., Parmar, D., & Yadav, S. (2015). Critical role of the miR‐200 family in regulating differentiation and proliferation of neurons. Journal of Neurochemistry, 133(5), 640–652. Portico. https://doi.org/10.1111/jnc.13089
Regulation of miR-34 Family in Neuronal Development
Molecular Neurobiology / Jan 13, 2017
Jauhari, A., Singh, T., Singh, P., Parmar, D., & Yadav, S. (2017). Regulation of miR-34 Family in Neuronal Development. Molecular Neurobiology, 55(2), 936–945. https://doi.org/10.1007/s12035-016-0359-4
Coordinated Action of miR-146a and Parkin Gene Regulate Rotenone-induced Neurodegeneration
Toxicological Sciences / May 11, 2020
Jauhari, A., Singh, T., Mishra, S., Shankar, J., & Yadav, S. (2020). Coordinated Action of miR-146a and Parkin Gene Regulate Rotenone-induced Neurodegeneration. Toxicological Sciences, 176(2), 433–445. https://doi.org/10.1093/toxsci/kfaa066
Neuronal mitochondrial dysfunction in sporadic amyotrophic lateral sclerosis is developmentally regulated
Scientific Reports / Sep 23, 2021
Singh, T., Jiao, Y., Ferrando, L. M., Yablonska, S., Li, F., Horoszko, E. C., Lacomis, D., Friedlander, R. M., & Carlisle, D. L. (2021). Neuronal mitochondrial dysfunction in sporadic amyotrophic lateral sclerosis is developmentally regulated. Scientific Reports, 11(1). https://doi.org/10.1038/s41598-021-97928-7
Role of microRNAs in neurodegeneration induced by environmental neurotoxicants and aging
Ageing Research Reviews / Jul 01, 2020
Singh, T., & Yadav, S. (2020). Role of microRNAs in neurodegeneration induced by environmental neurotoxicants and aging. Ageing Research Reviews, 60, 101068. https://doi.org/10.1016/j.arr.2020.101068
Differentiation Induces Dramatic Changes in miRNA Profile, Where Loss of Dicer Diverts Differentiating SH-SY5Y Cells Toward Senescence
Molecular Neurobiology / Aug 15, 2016
Jauhari, A., Singh, T., Pandey, A., Singh, P., Singh, N., Srivastava, A. K., Pant, A. B., Parmar, D., & Yadav, S. (2016). Differentiation Induces Dramatic Changes in miRNA Profile, Where Loss of Dicer Diverts Differentiating SH-SY5Y Cells Toward Senescence. Molecular Neurobiology, 54(7), 4986–4995. https://doi.org/10.1007/s12035-016-0042-9
Transactivation of P53 by cypermethrin induced miR-200 and apoptosis in neuronal cells
Toxicology Research / Jan 01, 2015
Pandey, A., Jauhari, A., Singh, T., Singh, P., Singh, N., Srivastava, A. K., Khan, F., Pant, A. B., Parmar, D., & Yadav, S. (2015). Transactivation of P53 by cypermethrin induced miR-200 and apoptosis in neuronal cells. Toxicology Research, 4(6), 1578–1586. https://doi.org/10.1039/c5tx00200a
Expression of miR-145 and Its Target Proteins Are Regulated by miR-29b in Differentiated Neurons
Molecular Neurobiology / Apr 04, 2018
Jauhari, A., Singh, T., & Yadav, S. (2018). Expression of miR-145 and Its Target Proteins Are Regulated by miR-29b in Differentiated Neurons. Molecular Neurobiology, 55(12), 8978–8990. https://doi.org/10.1007/s12035-018-1009-9
Regulatory Triangle of Neurodegeneration, Adult Neurogenesis and MicroRNAs
CNS & Neurological Disorders - Drug Targets / Feb 01, 2014
Singh, T., Jauhari, A., Pandey, A., Singh, P., Pant, A., Parmar, D., & Yadav, S. (2014). Regulatory Triangle of Neurodegeneration, Adult Neurogenesis and MicroRNAs. CNS & Neurological Disorders - Drug Targets, 13(1), 96–103. https://doi.org/10.2174/18715273113126660190
Melatonin inhibits cytosolic mitochondrial DNA–induced neuroinflammatory signaling in accelerated aging and neurodegeneration
Journal of Clinical Investigation / May 03, 2021
Jauhari, A., Baranov, S. V., Suofu, Y., Kim, J., Singh, T., Yablonska, S., Li, F., Wang, X., Oberly, P., Minnigh, M. B., Poloyac, S. M., Carlisle, D. L., & Friedlander, R. M. (2021). Melatonin inhibits cytosolic mitochondrial DNA–induced neuroinflammatory signaling in accelerated aging and neurodegeneration. Journal of Clinical Investigation, 131(9). https://doi.org/10.1172/jci150328
MicroRNAs are Emerging as Most Potential Molecular Biomarkers
Biochemistry & Analytical Biochemistry / Jan 01, 2015
Abhishek, S. Y. (2015). MicroRNAs are Emerging as Most Potential Molecular Biomarkers. Biochemistry & Analytical Biochemistry, 04(03). https://doi.org/10.4172/2161-1009.1000191
Neurodevelopmental disorders and neurotoxicity: MicroRNA in focus
Journal of Chemical Neuroanatomy / Mar 01, 2022
Jauhari, A., Singh, T., & Yadav, S. (2022). Neurodevelopmental disorders and neurotoxicity: MicroRNA in focus. Journal of Chemical Neuroanatomy, 120, 102072. https://doi.org/10.1016/j.jchemneu.2022.102072
Role of Stem Cells and Derived Exosomes as Novel Therapeutic Agents against Neuroinflammation and Stroke
Applications of Stem Cells and derived Exosomes in Neurodegenerative Disorders / Jan 01, 2023
Mirza, R. S., Rawat, N., Thakur, D., Bhardwaj, A., Gairola, S., & Singh, T. (2023). Role of Stem Cells and Derived Exosomes as Novel Therapeutic Agents against Neuroinflammation and Stroke. In Applications of Stem Cells and derived Exosomes in Neurodegenerative Disorders (pp. 193–230). Springer Nature Singapore. https://doi.org/10.1007/978-981-99-3848-3_9
Ageing at Molecular Level: Role of MicroRNAs
Biochemistry and Cell Biology of Ageing: Part III Biomedical Science / Jan 01, 2023
Yadav, S., Sarkar, S., Pandey, A., & Singh, T. (2023). Ageing at Molecular Level: Role of MicroRNAs. In Subcellular Biochemistry (pp. 195–248). Springer International Publishing. https://doi.org/10.1007/978-3-031-21410-3_9
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