Aisling Ní Cheallaigh, PhD

Senior Experimental Officer in glycosciene with experience in academia and industry and a proven track history is multidisciplinary research programs

Publications

Enzymatic Menthol Production: One-Pot Approach Using Engineered Escherichia coli

ACS Synthetic Biology

Structural Basis of Catalysis in the Bacterial Monoterpene Synthases Linalool Synthase and 1,8-Cineole Synthase

Oxidative Maturation and Structural Characterization of Prenylated FMN Binding by UbiD, a Decarboxylase Involved in Bacterial Ubiquinone Biosynthesis

Journal of Biological Chemistry

The UbiX flavin prenyltransferase reaction mechanism resembles class I terpene cyclase chemistry

Nature Communications

Pinpointing a Mechanistic Switch Between Ketoreduction and “Ene” Reduction in Short‐Chain Dehydrogenases/Reductases

Angewandte Chemie

Conjugation at the oligonucleotide level based on isoxazole phosphoramidites generated by click chemistry

Chemoenzymatic Synthesis of the Intermediates in the Peppermint Monoterpenoid Biosynthetic Pathway

Journal of Natural Products

Excited-State Properties of Protochlorophyllide Analogues and Implications for Light-Driven Synthesis of Chlorophyll

The Journal of Physical Chemistry B

Synthesis of building blocks for an iterative approach towards oligomers of theStreptococcus pneumoniaetype 1 zwitterionic capsular polysaccharide repeating unit

Canadian Journal of Chemistry

Preparation of Methyl 1,2,3,4-tetra-O-acetyl-β-D-glucopyranuronate

Organic Syntheses

Chemical synthesis of amphiphilic glycoconjugates: Access to amino, fluorinated and sulfhydryl oleyl glucosides

Carbohydrate Research

Synthesis of a B‐Antigen Hexasaccharide, a B‐Lewis b Heptasaccharide and Glycoconjugates Thereof to Investigate Binding Properties of Helicobacter pylori

Chemistry – A European Journal

Synthesis of type 1 Lewis b hexasaccharide antigen structures featuring flexible incorporation of l-[U-¹³C₆]-fucose for NMR binding studies

Organic & Biomolecular Chemistry

Natural Product Biosynthesis in Escherichia coli

Methods in Enzymology

Chemical synthesis of a sulfated d-glucosamine library and evaluation of cell proliferation capabilities

Carbohydrate Research

Strategies in Oligosaccharide Synthesis

Comprehensive Glycoscience

3’-O-β-Glycosylation of nucleoside analogues using a promiscuous bacterial glycosyltransferase

Virtual screening, identification and in vitro validation of small molecule GDP-mannose dehydrogenase inhibitors

RSC Chemical Biology

Synthesis of a Lewis b hexasaccharide thioglycoside donor and its use towards an extended mucin core Tn heptasaccharide structure and a photoreactive biotinylated serine linked hexasaccharide

Organic & Biomolecular Chemistry

NATURAL DEVELOPMENT OF ANTIBODIES AGAINST SEVERAL STREPTOCOCCUS PNEUMONIAE, HAEMOPHILUS INFLUENZAE, AND MORAXELLA CATARRHALIS PROTEIN ANTIGENS DURING THE FIRST 13 YEARS OF LIFE

Formation and immunological evaluation of Moraxella catarrhalis glycoconjugates based on synthetic oligosaccharides

Carbohydrate Polymers

An Alternative Synthesis of 3-Azidopropyl 2,4,6-Tri-O-Benzyl-β-d-Galactopyranosyl-(1→4)-2,3,6-Tri-O-Benzyl-β-d-Glucopyranoside

Carbohydrate Chemistry

Synthesis of Allyl α-(1→2)-Linked α-Mannobioside from a Common 1,2-Orthoacetate Precursor

Carbohydrate Chemistry

Excited-State Properties of Protochlorophyllide Analogues and Implications for Light-Driven Synthesis of Chlorophyll

Isoxazole linked oligonucleotide conjugates by on resin and previously clicked nitrile oxide alkyne cycloadditions

Collection Symposium Series

Excited‐State Charge Separation in the Photochemical Mechanism of the Light‐Driven Enzyme Protochlorophyllide Oxidoreductase

Angewandte Chemie

Cover Feature: Harnessing a Biocatalyst to Bioremediate the Purification of Alkylglycosides (ChemBioChem 1/2024)

Harnessing a Biocatalyst to Bioremediate the Purification of Alkylglycosides

Xylosyltransferase Bump-and-hole Engineering to Chemically Manipulate Proteoglycans in Mammalian Cells

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