Matthew Laye, Ph.D.
Medical Physiology Teacher, Data Scientist, Endurance Coach, Wearable Technology Consultant, Writer About Research
Research Expertise
Publications
Lack of Exercise Is a Major Cause of Chronic Diseases
Comprehensive Physiology / Apr 01, 2012
Booth, F. W., Roberts, C. K., & Laye, M. J. (2012). Lack of Exercise Is a Major Cause of Chronic Diseases. Comprehensive Physiology, 1143–1211. Portico. https://doi.org/10.1002/cphy.c110025
Mitochondrial dysfunction precedes insulin resistance and hepatic steatosis and contributes to the natural history of non-alcoholic fatty liver disease in an obese rodent model
Journal of Hepatology / May 01, 2010
Rector, R. S., Thyfault, J. P., Uptergrove, G. M., Morris, E. M., Naples, S. P., Borengasser, S. J., Mikus, C. R., Laye, M. J., Laughlin, M. H., Booth, F. W., & Ibdah, J. A. (2010). Mitochondrial dysfunction precedes insulin resistance and hepatic steatosis and contributes to the natural history of non-alcoholic fatty liver disease in an obese rodent model. Journal of Hepatology, 52(5), 727–736. https://doi.org/10.1016/j.jhep.2009.11.030
Muscle specific microRNAs are regulated by endurance exercise in human skeletal muscle
The Journal of Physiology / Oct 14, 2010
Nielsen, S., Scheele, C., Yfanti, C., Åkerström, T., Nielsen, A. R., Pedersen, B. K., & Laye, M. (2010). Muscle specific microRNAs are regulated by endurance exercise in human skeletal muscle. The Journal of Physiology, 588(20), 4029–4037. Portico. https://doi.org/10.1113/jphysiol.2010.189860
Daily exercise increases hepatic fatty acid oxidation and prevents steatosis in Otsuka Long-Evans Tokushima Fatty rats
American Journal of Physiology-Gastrointestinal and Liver Physiology / Mar 01, 2008
Rector, R. S., Thyfault, J. P., Morris, R. T., Laye, M. J., Borengasser, S. J., Booth, F. W., & Ibdah, J. A. (2008). Daily exercise increases hepatic fatty acid oxidation and prevents steatosis in Otsuka Long-Evans Tokushima Fatty rats. American Journal of Physiology-Gastrointestinal and Liver Physiology, 294(3), G619–G626. https://doi.org/10.1152/ajpgi.00428.2007
The miRNA Plasma Signature in Response to Acute Aerobic Exercise and Endurance Training
PLoS ONE / Feb 19, 2014
Nielsen, S., Åkerström, T., Rinnov, A., Yfanti, C., Scheele, C., Pedersen, B. K., & Laye, M. J. (2014). The miRNA Plasma Signature in Response to Acute Aerobic Exercise and Endurance Training. PLoS ONE, 9(2), e87308. https://doi.org/10.1371/journal.pone.0087308
Association Between Cardiorespiratory Fitness and the Determinants of Glycemic Control Across the Entire Glucose Tolerance Continuum
Diabetes Care / Mar 17, 2015
Solomon, T. P. J., Malin, S. K., Karstoft, K., Knudsen, S. H., Haus, J. M., Laye, M. J., & Kirwan, J. P. (2015). Association Between Cardiorespiratory Fitness and the Determinants of Glycemic Control Across the Entire Glucose Tolerance Continuum. Diabetes Care, 38(5), 921–929. https://doi.org/10.2337/dc14-2813
The effects of age and dietary restriction
on the tissue‐specific metabolome of
D
rosophila
Aging Cell / Jun 18, 2015
Laye, M. J., Tran, V., Jones, D. P., Kapahi, P., & Promislow, D. E. L. (2015). The effects of age and dietary restriction on the tissue‐specific metabolome of <scp>D</scp> rosophila . Aging Cell, 14(5), 797–808. Portico. https://doi.org/10.1111/acel.12358
Muscle specific miRNAs are induced by testosterone and independently upregulated by age
Frontiers in Physiology / Jan 01, 2014
Nielsen, S., Hvid, T., Kelly, M., Lindegaard, B., Dethlefsen, C., Winding, K., Mathur, N., Scheele, C., Pedersen, B. K., & Laye, M. J. (2014). Muscle specific miRNAs are induced by testosterone and independently upregulated by age. Frontiers in Physiology, 4. https://doi.org/10.3389/fphys.2013.00394
Skeletal Muscle to Pancreatic β-Cell Cross-talk: The Effect of Humoral Mediators Liberated by Muscle Contraction and Acute Exercise on β-Cell Apoptosis
The Journal of Clinical Endocrinology & Metabolism / Oct 01, 2015
Christensen, C. S., Christensen, D. P., Lundh, M., Dahllöf, M. S., Haase, T. N., Velasquez, J. M., Laye, M. J., Mandrup-Poulsen, T., & Solomon, T. P. J. (2015). Skeletal Muscle to Pancreatic β-Cell Cross-talk: The Effect of Humoral Mediators Liberated by Muscle Contraction and Acute Exercise on β-Cell Apoptosis. The Journal of Clinical Endocrinology & Metabolism, 100(10), E1289–E1298. https://doi.org/10.1210/jc.2014-4506
Immediate post-breakfast physical activity improves interstitial postprandial glycemia: a comparison of different activity-meal timings
Pflügers Archiv - European Journal of Physiology / Aug 08, 2019
Solomon, T. P. J., Tarry, E., Hudson, C. O., Fitt, A. I., & Laye, M. J. (2019). Immediate post-breakfast physical activity improves interstitial postprandial glycemia: a comparison of different activity-meal timings. Pflügers Archiv - European Journal of Physiology, 472(2), 271–280. https://doi.org/10.1007/s00424-019-02300-4
Targeting Postprandial Hyperglycemia With Physical Activity May Reduce Cardiovascular Disease Risk. But What Should We Do, and When Is the Right Time to Move?
Frontiers in Cardiovascular Medicine / Jul 18, 2018
Solomon, T. P. J., Eves, F. F., & Laye, M. J. (2018). Targeting Postprandial Hyperglycemia With Physical Activity May Reduce Cardiovascular Disease Risk. But What Should We Do, and When Is the Right Time to Move? Frontiers in Cardiovascular Medicine, 5. https://doi.org/10.3389/fcvm.2018.00099
Physical Activity Enhances Metabolic Fitness Independently of Cardiorespiratory Fitness in Marathon Runners
Disease Markers / Jan 01, 2015
Laye, M. J., Nielsen, M. B., Hansen, L. S., Knudsen, T., & Pedersen, B. K. (2015). Physical Activity Enhances Metabolic Fitness Independently of Cardiorespiratory Fitness in Marathon Runners. Disease Markers, 2015, 1–11. https://doi.org/10.1155/2015/806418
Determining pancreatic β-cell compensation for changing insulin sensitivity using an oral glucose tolerance test
American Journal of Physiology-Endocrinology and Metabolism / Nov 01, 2014
Solomon, T. P. J., Malin, S. K., Karstoft, K., Knudsen, S. H., Haus, J. M., Laye, M. J., Pedersen, M., Pedersen, B. K., & Kirwan, J. P. (2014). Determining pancreatic β-cell compensation for changing insulin sensitivity using an oral glucose tolerance test. American Journal of Physiology-Endocrinology and Metabolism, 307(9), E822–E829. https://doi.org/10.1152/ajpendo.00269.2014
Daily Marathon Running for a Week—The Biochemical and Body Compositional Effects of Participation
Journal of Strength and Conditioning Research / Nov 01, 2013
Karstoft, K., Solomon, T. P., Laye, M. J., & Pedersen, B. K. (2013). Daily Marathon Running for a Week—The Biochemical and Body Compositional Effects of Participation. Journal of Strength and Conditioning Research, 27(11), 2927–2933. https://doi.org/10.1519/jsc.0b013e318289e39d
Book of Abstracts of the 57th Annual Meeting of the European Association for Animal Production
Jan 01, 2006
van der Honing, Y. (Ed.). (2006). Book of Abstracts of the 57th Annual Meeting of the European Association for Animal Production. https://doi.org/10.3920/978-90-8686-580-2
Multi-Institutional Survey of Faculty Experiences Teaching Capstones
College Teaching / Jul 01, 2020
Laye, M. J., Boswell, C., Gresham, M., Smith-Sherwood, D., & Anderson, O. S. (2020). Multi-Institutional Survey of Faculty Experiences Teaching Capstones. College Teaching, 68(4), 201–213. https://doi.org/10.1080/87567555.2020.1786663
Acute Exercise and Ca2+ Stimulation Regulate Enzymes Involved in DNA Methylation in Human Skeletal Muscle
Medicine & Science in Sports & Exercise / Oct 01, 2010
Laye, M. J., & Pedersen, B. K. (2010). Acute Exercise and Ca2+ Stimulation Regulate Enzymes Involved in DNA Methylation in Human Skeletal Muscle. Medicine & Science in Sports & Exercise, 42(10), 23. https://doi.org/10.1249/01.mss.0000389529.44261.23
Human visceral and subcutaneous adipose stem and progenitor cells retain depot-specific adipogenic properties during obesity
Frontiers in Cell and Developmental Biology / Oct 17, 2022
Mathur, N., Severinsen, M. C. K., Jensen, M. E., Naver, L., Schrölkamp, M., Laye, M. J., Watt, M. J., Nielsen, S., Krogh-Madsen, R., Pedersen, B. K., & Scheele, C. (2022). Human visceral and subcutaneous adipose stem and progenitor cells retain depot-specific adipogenic properties during obesity. Frontiers in Cell and Developmental Biology, 10. https://doi.org/10.3389/fcell.2022.983899
Understanding Faculty Needs in Capstone Experiences
Cultivating Capstones / Jun 22, 2023
Gresham, M., Boswell, C., Anderson, O. S., Laye, M. J., & Smith-Sherwood, D. (2023). Understanding Faculty Needs in Capstone Experiences. Cultivating Capstones, 167–178. https://doi.org/10.4324/9781003443933-15
Immediate Post-breakfast Physical Activity Improves Postprandial Glycemia To High And Low Glycemic Index Mixed Meals
Medicine & Science in Sports & Exercise / Sep 01, 2022
Rowe, L. T., Laye, M. J., & Crissey, J. M. (2022). Immediate Post-breakfast Physical Activity Improves Postprandial Glycemia To High And Low Glycemic Index Mixed Meals. Medicine & Science in Sports & Exercise, 54(9S), 533–533. https://doi.org/10.1249/01.mss.0000881756.42113.f9
The Effect Of Arm Versus Leg Dominant Physical Activity On Postprandial Blood Glucose Levels
Medicine & Science in Sports & Exercise / Jul 01, 2020
Madrigal, K. C., Powley, E. R., & Laye, M. J. (2020). The Effect Of Arm Versus Leg Dominant Physical Activity On Postprandial Blood Glucose Levels. Medicine & Science in Sports & Exercise, 52(7S), 595–595. https://doi.org/10.1249/01.mss.0000680724.72161.af
729-P: Post-Breakfast Physical Activity Is Most Optimal for Improving Postprandial Glycemic Control in Healthy Adults
Diabetes / Jun 01, 2019
SOLOMON, T. P., TARRY, E., HUDSON, C. O., FITT, A. I., & LAYE, M. (2019). 729-P: Post-Breakfast Physical Activity Is Most Optimal for Improving Postprandial Glycemic Control in Healthy Adults. Diabetes, 68(Supplement_1). https://doi.org/10.2337/db19-729-p
Role of TLR4 in endoplasmic reticulum stress induced by physical exercise in skeletal muscle
Marafon, B. B. (n.d.). Role of TLR4 in endoplasmic reticulum stress induced by physical exercise in skeletal muscle. https://doi.org/10.11606/d.109.2022.tde-19092022-073341
Myomir Expression Pattern Across Gender And Age
Medicine & Science in Sports & Exercise / Oct 01, 2010
Nielsen, S., Kelly, M., Hvid, T., Mathur, N., Laye, M. J., & Pedersen, B. K. (2010). Myomir Expression Pattern Across Gender And Age. Medicine & Science in Sports & Exercise, 42(10), 89. https://doi.org/10.1249/01.mss.0000389439.07997.9e
The effects of physical activity on adipose tissue metabolism and DNA methylation
Laye, M. J. (n.d.). The effects of physical activity on adipose tissue metabolism and DNA methylation. https://doi.org/10.32469/10355/6160
The Effects of Exercise and Obesity on Adipose Tissue Mitochondria
Medicine & Science in Sports & Exercise / May 01, 2009
Laye, M. (2009). The Effects of Exercise and Obesity on Adipose Tissue Mitochondria. Medicine & Science in Sports & Exercise, 41(5), 22. https://doi.org/10.1249/01.mss.0000352791.98338.c5
Physical activity prevents endothelial dysfunction induced by sedentary life style and high fat diet in murine coronary microcirculation
The FASEB Journal / Apr 01, 2009
Park, Y., Lee, S., Booth, F. W., Laye, M. J., & Zhang, C. (2009). Physical activity prevents endothelial dysfunction induced by sedentary life style and high fat diet in murine coronary microcirculation. The FASEB Journal, 23(S1). Portico. https://doi.org/10.1096/fasebj.23.1_supplement.952.4
T1620 Loss of Mitochondrial Content and Function Contribute to the Natural History of Nonalcoholic Fatty Liver Disease in a Hyperphagic Obese Rodent Model
Gastroenterology / May 01, 2009
Rector, S., Thyfault, J. P., Uptergrove, G. M., Morris, E. M., Naples, S. P., Borengasser, S. J., Mikus, C. R., Laye, M. J., Laughlin, M. H., Booth, F. W., & Ibdah, J. A. (2009). T1620 Loss of Mitochondrial Content and Function Contribute to the Natural History of Nonalcoholic Fatty Liver Disease in a Hyperphagic Obese Rodent Model. Gastroenterology, 136(5), A-850. https://doi.org/10.1016/s0016-5085(09)63920-2
S1894 Physical Activity and Short-Term Inactivity Modulate Hepatic Fatty Acid Oxidation and Lipogenesis Proteins in Otsuka Long-Evans Tokushima Fatty (Oletf) Rats
Gastroenterology / Apr 01, 2008
Rector, S., Thyfault, J. P., Laye, M. J., Morris, R. T., Borengasser, S. J., Uptergrove, G. M., Booth, F. W., & Ibdah, J. A. (2008). S1894 Physical Activity and Short-Term Inactivity Modulate Hepatic Fatty Acid Oxidation and Lipogenesis Proteins in Otsuka Long-Evans Tokushima Fatty (Oletf) Rats. Gastroenterology, 134(4), A-778-A-779. https://doi.org/10.1016/s0016-5085(08)63636-7
Effect of moderate fat/high sucrose diet on glycogen synthesis rates in rat skeletal muscle upon the cessation of voluntary wheel running
The FASEB Journal / Apr 01, 2007
Borengasser, S. J., Laye, M., Morris, T., Booth, F., & Thyfault, J. (2007). Effect of moderate fat/high sucrose diet on glycogen synthesis rates in rat skeletal muscle upon the cessation of voluntary wheel running. The FASEB Journal, 21(5). Portico. https://doi.org/10.1096/fasebj.21.5.a691-a
Adipose tissue compensates to maintain whole body insulin sensitivity 173 hours following the cessation of voluntary running in rats
The FASEB Journal / Jan 01, 2007
Laye, M. J., Borengasser, S. J., Rector, R. S., Thyfault, J. P., & Booth, F. W. (2007). Adipose tissue compensates to maintain whole body insulin sensitivity 173 hours following the cessation of voluntary running in rats. The FASEB Journal, 21(6). Portico. https://doi.org/10.1096/fasebj.21.6.a936
Increased Fat Mass Occurs Independently of Caloric Intake During Inactivity
Medicine & Science in Sports & Exercise / Nov 01, 2006
Laye, M. J., & Booth, F. (2006). Increased Fat Mass Occurs Independently of Caloric Intake During Inactivity. Medicine & Science in Sports & Exercise, 38(Suppl 1), S44. https://doi.org/10.1249/00005768-200611001-00172
Different Immunological Phenotypes Associated with Preserved CD4+ T Cell Counts in HIV-Infected Controllers and Viremic Long Term Non-Progressors
PLoS ONE / May 16, 2013
Gaardbo, J. C., Hartling, H. J., Ronit, A., Thorsteinsson, K., Madsen, H. O., Springborg, K., Gjerdrum, L. M. R., Birch, C., Laye, M., Ullum, H., Andersen, Å. B., & Nielsen, S. D. (2013). Different Immunological Phenotypes Associated with Preserved CD4+ T Cell Counts in HIV-Infected Controllers and Viremic Long Term Non-Progressors. PLoS ONE, 8(5), e63744. https://doi.org/10.1371/journal.pone.0063744
Impaired Thymic Output in Patients with Chronic Hepatitis C Virus Infection
Scandinavian Journal of Immunology / Sep 12, 2013
Hartling, H. J., Gaardbo, J. C., Ronit, A., Salem, M., Laye, M., Clausen, M. R., Skogstrand, K., Gerstoft, J., Ullum, H., & Nielsen, S. D. (2013). Impaired Thymic Output in Patients with Chronic Hepatitis C Virus Infection. Scandinavian Journal of Immunology, 78(4), 378–386. https://doi.org/10.1111/sji.12096
Increased shelterin mRNA expression in peripheral blood mononuclear cells and skeletal muscle following an ultra-long-distance running event
Journal of Applied Physiology / Mar 01, 2012
Laye, M. J., Solomon, T. P. J., Karstoft, K., Pedersen, K. K., Nielsen, S. D., & Pedersen, B. K. (2012). Increased shelterin mRNA expression in peripheral blood mononuclear cells and skeletal muscle following an ultra-long-distance running event. Journal of Applied Physiology, 112(5), 773–781. https://doi.org/10.1152/japplphysiol.00997.2011
Physical activity opposes coronary vascular dysfunction induced during high fat feeding in mice
The Journal of Physiology / Jul 27, 2012
Park, Y., Booth, F. W., Lee, S., Laye, M. J., & Zhang, C. (2012). Physical activity opposes coronary vascular dysfunction induced during high fat feeding in mice. The Journal of Physiology, 590(17), 4255–4268. Portico. https://doi.org/10.1113/jphysiol.2012.234856
LIF is a contraction-induced myokine stimulating human myocyte proliferation
Journal of Applied Physiology / Jul 01, 2011
Broholm, C., Laye, M. J., Brandt, C., Vadalasetty, R., Pilegaard, H., Pedersen, B. K., & Scheele, C. (2011). LIF is a contraction-induced myokine stimulating human myocyte proliferation. Journal of Applied Physiology, 111(1), 251–259. https://doi.org/10.1152/japplphysiol.01399.2010
Lifetime sedentary living accelerates some aspects of secondary aging
Journal of Applied Physiology / Nov 01, 2011
Booth, F. W., Laye, M. J., & Roberts, M. D. (2011). Lifetime sedentary living accelerates some aspects of secondary aging. Journal of Applied Physiology, 111(5), 1497–1504. https://doi.org/10.1152/japplphysiol.00420.2011
Changes in skeletal muscle mitochondria in response to the development of type 2 diabetes or prevention by daily wheel running in hyperphagic OLETF rats
American Journal of Physiology-Endocrinology and Metabolism / Jun 01, 2010
Rector, R. S., Uptergrove, G. M., Borengasser, S. J., Mikus, C. R., Morris, E. M., Naples, S. P., Laye, M. J., Laughlin, M. H., Booth, F. W., Ibdah, J. A., & Thyfault, J. P. (2010). Changes in skeletal muscle mitochondria in response to the development of type 2 diabetes or prevention by daily wheel running in hyperphagic OLETF rats. American Journal of Physiology-Endocrinology and Metabolism, 298(6), E1179–E1187. https://doi.org/10.1152/ajpendo.00703.2009
Gold standards for scientists who are conducting animal-based exercise studies
Journal of Applied Physiology / Jan 01, 2010
Booth, F. W., Laye, M. J., & Spangenburg, E. E. (2010). Gold standards for scientists who are conducting animal-based exercise studies. Journal of Applied Physiology, 108(1), 219–221. https://doi.org/10.1152/japplphysiol.00125.2009
Last Word on Viewpoint: Gold standards for scientists who are conducting animal-based exercise studies
Journal of Applied Physiology / Jan 01, 2010
Booth, F. W., Laye, M. J., & Spangenburg, E. E. (2010). Last Word on Viewpoint: Gold standards for scientists who are conducting animal-based exercise studies. Journal of Applied Physiology, 108(1), 226–226. https://doi.org/10.1152/japplphysiol.01232.2009
The future: genes, physical activity and health
Acta Physiologica / Jul 01, 2010
Booth, F. W., & Laye, M. J. (2010). The future: genes, physical activity and health. Acta Physiologica, 199(4), 549–556. Portico. https://doi.org/10.1111/j.1748-1716.2010.02117.x
Cessation of daily wheel running differentially alters fat oxidation capacity in liver, muscle, and adipose tissue
Journal of Applied Physiology / Jan 01, 2009
Laye, M. J., Rector, R. S., Borengasser, S. J., Naples, S. P., Uptergrove, G. M., Ibdah, J. A., Booth, F. W., & Thyfault, J. P. (2009). Cessation of daily wheel running differentially alters fat oxidation capacity in liver, muscle, and adipose tissue. Journal of Applied Physiology, 106(1), 161–168. https://doi.org/10.1152/japplphysiol.91186.2008
Changes in visceral adipose tissue mitochondrial content with type 2 diabetes and daily voluntary wheel running in OLETF rats
The Journal of Physiology / Jul 14, 2009
Laye, M. J., Rector, R. S., Warner, S. O., Naples, S. P., Perretta, A. L., Uptergrove, G. M., Laughlin, M. H., Thyfault, J. P., Booth, F. W., & Ibdah, J. A. (2009). Changes in visceral adipose tissue mitochondrial content with type 2 diabetes and daily voluntary wheel running in OLETF rats. The Journal of Physiology, 587(14), 3729–3739. Portico. https://doi.org/10.1113/jphysiol.2009.172601
Lack of adequate appreciation of physical exercise's complexities can pre-empt appropriate design and interpretation in scientific discovery
The Journal of Physiology / Nov 30, 2009
Booth, F. W., & Laye, M. J. (2009). Lack of adequate appreciation of physical exercise’s complexities can pre-empt appropriate design and interpretation in scientific discovery. The Journal of Physiology, 587(23), 5527–5539. Portico. https://doi.org/10.1113/jphysiol.2009.179507
Novel epigenetic regulation of skeletal muscle myosin heavy chain genes. Focus on “Differential epigenetic modifications of histones at the myosin heavy chain genes in fast and slow skeletal muscle fibers and in response to muscle unloading”
American Journal of Physiology-Cell Physiology / Jul 01, 2009
Zwetsloot, K. A., Laye, M. J., & Booth, F. W. (2009). Novel epigenetic regulation of skeletal muscle myosin heavy chain genes. Focus on “Differential epigenetic modifications of histones at the myosin heavy chain genes in fast and slow skeletal muscle fibers and in response to muscle unloading.” American Journal of Physiology-Cell Physiology, 297(1), C1–C3. https://doi.org/10.1152/ajpcell.00176.2009
Rats selectively bred for low aerobic capacity have reduced hepatic mitochondrial oxidative capacity and susceptibility to hepatic steatosis and injury
The Journal of Physiology / Apr 14, 2009
Thyfault, J. P., Rector, R. S., Uptergrove, G. M., Borengasser, S. J., Morris, E. M., Wei, Y., Laye, M. J., Burant, C. F., Qi, N. R., Ridenhour, S. E., Koch, L. G., Britton, S. L., & Ibdah, J. A. (2009). Rats selectively bred for low aerobic capacity have reduced hepatic mitochondrial oxidative capacity and susceptibility to hepatic steatosis and injury. The Journal of Physiology, 587(8), 1805–1816. Portico. https://doi.org/10.1113/jphysiol.2009.169060
Cessation of daily exercise dramatically alters precursors of hepatic steatosis in Otsuka Long-Evans Tokushima Fatty (OLETF) rats
The Journal of Physiology / Sep 01, 2008
Rector, R. S., Thyfault, J. P., Laye, M. J., Morris, R. T., Borengasser, S. J., Uptergrove, G. M., Chakravarthy, M. V., Booth, F. W., & Ibdah, J. A. (2008). Cessation of daily exercise dramatically alters precursors of hepatic steatosis in Otsuka Long-Evans Tokushima Fatty (OLETF) rats. The Journal of Physiology, 586(17), 4241–4249. Portico. https://doi.org/10.1113/jphysiol.2008.156745
Exercise-induced attenuation of obesity, hyperinsulinemia, and skeletal muscle lipid peroxidation in the OLETF rat
Journal of Applied Physiology / Mar 01, 2008
Morris, R. T., Laye, M. J., Lees, S. J., Rector, R. S., Thyfault, J. P., & Booth, F. W. (2008). Exercise-induced attenuation of obesity, hyperinsulinemia, and skeletal muscle lipid peroxidation in the OLETF rat. Journal of Applied Physiology, 104(3), 708–715. https://doi.org/10.1152/japplphysiol.01034.2007
Reduced physical activity and risk of chronic disease: the biology behind the consequences
European Journal of Applied Physiology / Nov 07, 2007
Booth, F. W., Laye, M. J., Lees, S. J., Rector, R. S., & Thyfault, J. P. (2007). Reduced physical activity and risk of chronic disease: the biology behind the consequences. European Journal of Applied Physiology, 102(4), 381–390. https://doi.org/10.1007/s00421-007-0606-5
Inactivity induces increases in abdominal fat
Journal of Applied Physiology / Apr 01, 2007
Laye, M. J., Thyfault, J. P., Stump, C. S., & Booth, F. W. (2007). Inactivity induces increases in abdominal fat. Journal of Applied Physiology, 102(4), 1341–1347. https://doi.org/10.1152/japplphysiol.01018.2006
Increased mitochondrial glycerol-3-phosphate acyltransferase protein and enzyme activity in rat epididymal fat upon cessation of wheel running
American Journal of Physiology-Endocrinology and Metabolism / Mar 01, 2006
Kump, D. S., Laye, M. J., & Booth, F. W. (2006). Increased mitochondrial glycerol-3-phosphate acyltransferase protein and enzyme activity in rat epididymal fat upon cessation of wheel running. American Journal of Physiology-Endocrinology and Metabolism, 290(3), E480–E489. https://doi.org/10.1152/ajpendo.00321.2005
Education
University of Missouri
Ph.D, Medical Physiology / June, 2009
University of California, Davis
BS, Exercise Biology / December, 2004
Experience
Idaho College of Osteopathic Medicine
Associate Professor Physiology / March, 2022 — Present
The College of Idaho
Assistant/Associate/Chair / September, 2015 — March, 2022
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