SANDIP MUKHERJEE

Scientist with diverse knowledge in infectious diseases, inflammation, drug development, protac, in vitro and in vivo pharmacology of small moleculae and biologics

Research Expertise

infectious diseases
immunology
therapy
Inflammation

About

SANDIP MUKHERJEE is a highly accomplished scientist with a Ph.D in Biotechnology from the University of Calcutta. He obtained his degree in 2015 and has since then gained extensive experience in the field of biotechnology. His education and experience have equipped him with a strong foundation in the fundamentals of biotechnology and have enabled him to become an expert in the field. After completing his Ph.D, SANDIP MUKHERJEE worked as a Postdoctoral Researcher at Baylor University Medical Center and University of Texas Southwestern Medical Center. During this time, he conducted research on various topics such as cancer biology, stem cells, and regenerative medicine. His research has been published in several renowned scientific journals, showcasing his ability to produce high-quality and impactful research. Following his postdoctoral positions, SANDIP MUKHERJEE joined Nektar Therapeutics as a Scientist where he played a key role in developing new drug delivery technologies. He then moved on to Nurix Therapeutics as a Scientist II, where he focused on developing novel therapies for cancer and autoimmune diseases. His contributions to both companies have been instrumental in advancing their research and development efforts. SANDIP MUKHERJEE's expertise lies in various areas of biotechnology including molecular biology, cell biology, protein engineering, and drug development. He is known for his innovative thinking, attention to detail, and strong analytical skills, which have helped him excel in his career. In addition to his professional achievements, SANDIP MUKHERJEE is also passionate about mentoring and educating the next generation of scientists. He has served as a guest lecturer at several universities and has mentored numerous students and young researchers. Overall, SANDIP MUKHERJEE is a highly skilled and accomplished scientist with a strong passion for biotechnology. His education, experience, and contributions to the field make him a valuable asset to any organization.

Publications

Antimony-resistant but not antimony-sensitiveLeishmania donovaniup-regulates host IL-10 to overexpress multidrug-resistant protein 1
Proceedings of the National Academy of Sciences
2013
Characterisation of antimony-resistant Leishmania donovani isolates: Biochemical and biophysical studies and interaction with host cells
International Journal for Parasitology
2011
Deubiquitination of NLRP6 inflammasome by Cyld critically regulates intestinal inflammation
Nature Immunology
2020
Restoration of IFNγR Subunit Assembly, IFNγ Signaling and Parasite Clearance in Leishmania donovani Infected Macrophages: Role of Membrane Cholesterol
PLoS Pathogens
2011
Imipramine Is an Orally Active Drug against Both Antimony Sensitive and Resistant Leishmania donovani Clinical Isolates in Experimental Infection
PLoS Neglected Tropical Diseases
2012
Metabolic adaptations of Leishmania donovani in relation to differentiation, drug resistance, and drug pressure
Molecular Microbiology
2013
Imipramine Exploits Histone Deacetylase 11 To Increase the IL-12/IL-10 Ratio in Macrophages Infected with Antimony-Resistant Leishmania donovani and Clears Organ Parasites in Experimental Infection
The Journal of Immunology
2014
Antimony-ResistantLeishmania donovaniExploits miR-466i To Deactivate Host MyD88 for Regulating IL-10/IL-12 Levels during Early Hours of Infection
The Journal of Immunology
2015
Functionally significant metabolic differences between B and T lymphocyte lineages
Immunology
2019
Short-Course Treatment With Imipramine Entrapped in Squalene Liposomes Results in Sterile Cure of Experimental Visceral Leishmaniasis Induced by Antimony Resistant Leishmania donovani With Increased Efficacy
Frontiers in Cellular and Infection Microbiology
2020
A Novel Bioimpedance-Based Detection of Miltefosine Susceptibility Among Clinical Leishmania donovani Isolates of the Indian Subcontinent Exhibiting Resistance to Multiple Drugs
Frontiers in Cellular and Infection Microbiology
2021
Advancements in the analysis of protein post-translational modifications
Advances in Protein Molecular and Structural Biology Methods
2022
RORγt-Raftlin1 complex regulates the pathogenicity of Th17 cells and colonic inflammation
Nature Communications
2023
Cellular signaling, molecular activation, and regulation of the NLRP6 inflammasome
Inflammasome Biology
2023
Deubiquitination of NLRP6 by Cyld critically regulates colonic inflammation
The Journal of Immunology
2021

Education

University of Calcutta

Ph.D, Biotechnology / August, 2015

Kolkata

Experience

Baylor University Medical Center

Postdoctoral Researcher / March, 2016April, 2019

University of Texas Southwestern Medical Center

Postdoctoral Researcher / April, 2019September, 2022

Nektar Therapeutics

Scientist / September, 2022June, 2023

Nurix Therapeutics

Scientist II / June, 2023Present

Links & Social Media

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