Ishwarya Murali

Scientist, Nalo Therapeutics

Research Expertise

Cancer genomics
Immunology
Cell Biology
Hematology
Biochemistry
Virology
Infectious Diseases
Oncology
Cancer Research
Molecular Biology
Neuropsychology and Physiological Psychology
Psychiatry and Mental health

Publications

Activation of the MAPK pathway mediates resistance to PI3K inhibitors in chronic lymphocytic leukemia
Blood
2021
Activating MAPK Pathway Mutations Mediate Primary Resistance to PI3K Inhibitors in Chronic Lymphocytic Leukemia (CLL)
Blood
2018
"pp65 antigenemia and real time polymerase chain reaction (PCR) based-study to determine the prevalence of human cytomegalovirus (HCMV) in kidney donors and recipients with follow-up studies."
Virology Journal
2010
The effect of chronic alcohol consumption on mitochondrial calcium handling in hepatocytes
Biochemical Journal
2016
Functional Testing to Characterize and Stratify PI3K Inhibitor Responses in Chronic Lymphocytic Leukemia
Clinical Cancer Research
2022
Genetic events associated with venetoclax resistance in CLL identified by whole-exome sequencing of patient samples
Blood
2023
Functional testing of PI3K inhibitors stratifies responders to idelalisib and identifies treatment vulnerabilities in idelalisib-refractory/intolerant chronic lymphocytic leukemia
Unknown Venue
2022
Functional characterization of novel mutations in Ul54 of ganciclovir resistant HCMV strain using structural analysis
Bioinformation
2011
Potential Drivers of Acquired Resistance to Idelalisib in CLL Patients
Blood
2022
P626: FUNCTIONAL SCREENING OF PI3K INHIBITORS STRATIFIES RESPONDERS TO IDELALISIB AND INDICATES DRUG CLASS ACTIVITY IN IDELALISIB-REFRACTORY CLL
HemaSphere
2022
Abstract 1097: Mechanisms of primary and acquired resistance to venetoclax in chronic lymphocytic leukemia (CLL)
Cancer Research
2021
Stromal Carcinoma Associated Fibroblasts Promote Drug Resistance of Human Pancreatic Cancer Cells by Modulation of ROS via CXCR4/CXCL12 Signaling
International Journal of Translational Science
2015
Data from Functional Testing to Characterize and Stratify PI3K Inhibitor Responses in Chronic Lymphocytic Leukemia
Unknown Venue
2023
Data from Functional Testing to Characterize and Stratify PI3K Inhibitor Responses in Chronic Lymphocytic Leukemia
Unknown Venue
2023
Supplementary Figure from Functional Testing to Characterize and Stratify PI3K Inhibitor Responses in Chronic Lymphocytic Leukemia
Unknown Venue
2023
Supplementary Figure from Functional Testing to Characterize and Stratify PI3K Inhibitor Responses in Chronic Lymphocytic Leukemia
Unknown Venue
2023
Supplementary Figure from Functional Testing to Characterize and Stratify PI3K Inhibitor Responses in Chronic Lymphocytic Leukemia
Unknown Venue
2023
Supplementary Figure from Functional Testing to Characterize and Stratify PI3K Inhibitor Responses in Chronic Lymphocytic Leukemia
Unknown Venue
2023
Supplementary Figure from Functional Testing to Characterize and Stratify PI3K Inhibitor Responses in Chronic Lymphocytic Leukemia
Unknown Venue
2023
Supplementary Figure from Functional Testing to Characterize and Stratify PI3K Inhibitor Responses in Chronic Lymphocytic Leukemia
Unknown Venue
2023
Supplementary Figure from Functional Testing to Characterize and Stratify PI3K Inhibitor Responses in Chronic Lymphocytic Leukemia
Unknown Venue
2023
Supplementary Figure from Functional Testing to Characterize and Stratify PI3K Inhibitor Responses in Chronic Lymphocytic Leukemia
Unknown Venue
2023
Supplementary Table from Functional Testing to Characterize and Stratify PI3K Inhibitor Responses in Chronic Lymphocytic Leukemia
Unknown Venue
2023
Supplementary Table from Functional Testing to Characterize and Stratify PI3K Inhibitor Responses in Chronic Lymphocytic Leukemia
Unknown Venue
2023
Supplementary Table from Functional Testing to Characterize and Stratify PI3K Inhibitor Responses in Chronic Lymphocytic Leukemia
Unknown Venue
2023
Supplementary Table from Functional Testing to Characterize and Stratify PI3K Inhibitor Responses in Chronic Lymphocytic Leukemia
Unknown Venue
2023
Supplementary Table from Functional Testing to Characterize and Stratify PI3K Inhibitor Responses in Chronic Lymphocytic Leukemia
Unknown Venue
2023
Supplementary Table from Functional Testing to Characterize and Stratify PI3K Inhibitor Responses in Chronic Lymphocytic Leukemia
Unknown Venue
2023
Supplementary Table from Functional Testing to Characterize and Stratify PI3K Inhibitor Responses in Chronic Lymphocytic Leukemia
Unknown Venue
2023
Supplementary Table from Functional Testing to Characterize and Stratify PI3K Inhibitor Responses in Chronic Lymphocytic Leukemia
Unknown Venue
2023

Education

Rutgers University

Pharmacology & Physiology / August, 2017

Newark, New Jersey, United States of America

SASTRA University

B-Tech, Biotechnology / June, 2009

Thanjavur

Experience

Nalo Therapeutics

Scientist / October, 2022Present

Postdoctoral fellow / September, 2017May, 2020

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