Dr. Gaurav Mehta, Ph.D.

PhD Scientist with 13+ years of research experience in cancer biology, cell and molecular biology, genomics, metabolomics, and epigenetics

Research Expertise

Molecular Biology
Epigenetics
Cell Biology
Oncology
Stem cells
Immunology and Allergy
Immunology
Genetics
Cancer Research
Cardiology and Cardiovascular Medicine
Pharmacology (medical)
Radiology, Nuclear Medicine and imaging
Drug Discovery
Pharmacology

Legacy Map

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Publications

Tumor mutational burden is a determinant of immune-mediated survival in breast cancer
OncoImmunology
2018
BRG1 interacts with SOX10 to establish the melanocyte lineage and to promote differentiation
Nucleic Acids Research
2017
Amplification of SOX4 promotes PI3K/Akt signaling in human breast cancer
Breast Cancer Research and Treatment
2017
MITF interacts with the SWI/SNF subunit, BRG1, to promote GATA4 expression in cardiac hypertrophy
Journal of Molecular and Cellular Cardiology
2015
SWI/SNF Enzymes Promote SOX10- Mediated Activation of Myelin Gene Expression
PLoS ONE
2013
Emerging Role of SOX Proteins in Breast Cancer Development and Maintenance
Journal of Mammary Gland Biology and Neoplasia
2019
SWI/SNF Chromatin Remodeling Enzymes in Melanocyte Differentiation and Melanoma
Critical Reviews in Eukaryotic Gene Expression
2014
CPT1A and fatty acid β-oxidation are essential for tumor cell growth and survival in hormone receptor-positive breast cancer
NAR Cancer
2021
Integrative proteogenomic analyses of human tumours identifies ADNP as a novel oncogenic mediator of cell cycle progression in high-grade serous ovarian cancer with poor prognosis
EBioMedicine
2019
Recent Advances in Integrative Multi-Omics Research in Breast and Ovarian Cancer
Journal of Personalized Medicine
2021
FOXA1 and adaptive response determinants to HER2 targeted therapy in TBCRC 036
npj Breast Cancer
2021
SOX4 and SMARCA4 cooperatively regulate PI3k signaling through transcriptional activation of TGFBR2
npj Breast Cancer
2021
Abstract P2-03-03: BRG1-SOX4 mediates a novel and essential signaling network that activates PI3K/Akt signaling in TNBC
Cancer Research
2019
Abstract PD15-09: Sox4 and smarca4 upregulate glycolysis-driven tumor proliferation through hexokinase 2 in tnbc
Cancer Research
2021
Abstract PO-035: SOX4 and SMARCA4 upregulate glycolysis-driven tumor proliferation through Hexokinase 2 in Triple Negative Breast Cancer
Cancer Research
2020
Wound healing, anti-microbial and antioxidant potential of Dendrophthoe falcata (L.f) Ettingsh
Journal of Ethnopharmacology
2008

Education

Ph.D., Biochemistry and Cancer Biology / May, 2015

Toledo, Ohio, United States of America

University of Mumbai

M.Sc., Biotechnology / May, 2009

Mumbai

University of Mumbai

B.Sc., Biotechnology / May, 2007

Mumbai

Experience

Rutgers Cancer Institute of New Jersey

Post-Doctoral Researcher / April, 2016October, 2021

PMV Pharma

Research Scientist / May, 2022Present

WuXi Advanced Therapies

Scientist / November, 2021May, 2022

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