Jeffrey Townsend

Professor of Biostatistics and Ecology & Evolutionary Biology

New Haven, CT, Connecticut, United States of America

Research Expertise

Evolutionary Genomics
Microbiology
Infectious Diseases
Genetics
Cell Biology
Ecology, Evolution, Behavior and Systematics
Molecular Biology
Physiology
Biomedical Engineering
Molecular Medicine
Applied Microbiology and Biotechnology
Bioengineering
Biotechnology
Biochemistry
Biomaterials
Biophysics
Oncology
Hematology
Genetics (clinical)
Health Informatics
Computer Science Applications
Virology
Microbiology (medical)
Parasitology
Developmental Biology
Cancer Research
Information Systems
Pharmacology (medical)
Pharmacology
Public Health, Environmental and Occupational Health
Epidemiology
Applied Mathematics
Structural Biology
Immunology and Allergy
Immunology
Computational Mathematics
Computational Theory and Mathematics
Statistics and Probability
Animal Science and Zoology
Histology
Pathology and Forensic Medicine
Library and Information Sciences
Pulmonary and Respiratory Medicine
Modeling and Simulation
Health Policy
Internal Medicine
Neurology (clinical)
Cellular and Molecular Neuroscience
Ecology
Urology
Oral Surgery
Radiology, Nuclear Medicine and imaging
Radiation

About

Jeffrey Townsend is a Professor of Organismic and Evolutionary Biology at Yale University. He received his Ph.D. from Harvard University in 2002 and his Sc.B. from Brown University in 1994. He has been a teacher at St. Ann's School and an Assistant Professor at the University of Connecticut. He is currently the Elihu Professor of Biostatistics at Yale University.

Legacy Map

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Publications

A comprehensive phylogeny of birds (Aves) using targeted next-generation DNA sequencing
Nature
2015
Horizontal gene transfer, genome innovation and evolution
Nature Reviews Microbiology
2005
The Ascomycota Tree of Life: A Phylum-wide Phylogeny Clarifies the Origin and Evolution of Fundamental Reproductive and Ecological Traits
Systematic Biology
2009
Eukaryotic microbes, species recognition and the geographic limits of species: examples from the kingdom Fungi
Philosophical Transactions of the Royal Society B: Biological Sciences
2006
Strategies for containing Ebola in West Africa
Science
2014
Profiling Phylogenetic Informativeness
Systematic Biology
2007
Phylogenetic and phylogenomic overview of the Polyporales
Mycologia
2013
The durability of immunity against reinfection by SARS-CoV-2: a comparative evolutionary study
The Lancet Microbe
2021
Multifactorial experimental design and the transitivity of ratios with spotted DNA microarrays
BMC Genomics
2003
Gene expression profiling of mouse postnatal cerebellar development using cDNA microarrays
Gene
2004
Horizontal Acquisition of Divergent Chromosomal DNA in Bacteria: Effects of Mutator Phenotypes
Genetics
2003
Potential effectiveness of long-acting injectable pre-exposure prophylaxis for HIV prevention in men who have sex with men: a modelling study
The Lancet HIV
2018
Estimation of Neutral Mutation Rates and Quantification of Somatic Variant Selection Using cancereffectsizeR
Cancer Research
2022
Infection by SARS‐CoV‐2 with alternate frequencies of mRNA vaccine boosting
Journal of Medical Virology
2023
Jot: guiding journal selection with suitability metrics
Journal of the Medical Library Association
2022
In Response to “De Novo KRAS G12C-Mutant SCLC: A Case Report”
JTO Clinical and Research Reports
2022
Not only mutations but also tumorigenesis can be substantially attributed to DNA damage from reactive oxygen species in RUNX1::RUNX1T1-fusion-positive acute myeloid leukemia
Leukemia
2022
The durability of natural infection and vaccine-induced immunity against future infection by SARS-CoV-2
Proceedings of the National Academy of Sciences
2022
Cancer Relevance of Human Genes
JNCI: Journal of the National Cancer Institute
2022
Secondary Metabolism Gene Clusters Exhibit Increasingly Dynamic and Differential Expression during Asexual Growth, Conidiation, and Sexual Development in Neurospora crassa
mSystems
2022
Transcriptional Divergence Underpinning Sexual Development in the Fungal Class Sordariomycetes
mBio
2022
A phylogenetic approach to study the evolution of somatic mutational processes in cancer
Communications Biology
2022
Attribution of Cancer Origins to Endogenous, Exogenous, and Preventable Mutational Processes
Molecular Biology and Evolution
2022
Quarantine and testing strategies to ameliorate transmission due to travel during the COVID-19 pandemic: a modelling study
The Lancet Regional Health - Europe
2022
Premetastatic shifts of endogenous and exogenous mutational processes support consolidative therapy in EGFR-driven lung adenocarcinoma
Cancer Letters
2022
Projecting the seasonality of endemic COVID-19
Unknown Venue
2022
Pairwise and higher-order epistatic effects among somatic cancer mutations across oncogenesis
Unknown Venue
2022
Environmental and sex-specific molecular signatures of glioma causation
Neuro-Oncology
2021
The Prognostic Value of an RT-PCR Test for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Is Contingent on Timing across Disease Time Course in addition to Assay Sensitivity
The Journal of Molecular Diagnostics
2022
Heavy mutagenesis by tobacco leads to lung adenocarcinoma tumors with KRAS G12 mutations other than G12D, leading KRAS G12D tumors—on average—to exhibit a lower mutation burden
Lung Cancer
2022
Sequencing and Analysis of the Entire Genome of the Mycoparasitic Bioeffector Fungus Trichoderma asperelloides Strain T 203 (Hypocreales)
Microbiology Resource Announcements
2022
The somatic molecular evolution of cancer: Mutation, selection, and epistasis
Progress in Biophysics and Molecular Biology
2021
Chemsearch: collaborative compound libraries with structure-aware browsing
Bioinformatics Advances
2021
Mechanistic basis of post-treatment control of SIV after anti-α4β7 antibody therapy
PLOS Computational Biology
2021
Clinically relevant shifts in endogenous and exogenous mutational processes proximate to metastasis support local consolidative treatment in EGFR-driven non-small cell lung cancer
Unknown Venue
2021
Quarantine and testing strategies to ameliorate transmission due to travel during the COVID-19 pandemic: a modelling study
Unknown Venue
2021
Optimal COVID-19 quarantine and testing strategies
Nature Communications
2021
Cancer relevance of human genes
Unknown Venue
2021
Comparative analyses of FDA EUA-approved rapid antigen tests and RT-PCR for COVID-19 quarantine and surveillance-based isolation
Unknown Venue
2021
Identifying modules of cooperating cancer drivers
Molecular Systems Biology
2021
Comparative Genomics within and across Bilaterians Illuminates the Evolutionary History of ALK and LTK Proto-Oncogene Origination and Diversification
Genome Biology and Evolution
2020
Attribution of Cancer Origins to Endogenous, Exogenous, and Actionable Mutational Processes
Unknown Venue
2020
Unmatched Level of Molecular Convergence among Deeply Divergent Complex Multicellular Fungi
Molecular Biology and Evolution
2020
Non-Coding Mutations in Urothelial Bladder Cancer: Biological and Clinical Relevance and Potential Utility as Biomarkers
Bladder Cancer
2020
Germline variant burden in cancer genes correlates with age at diagnosis and somatic mutation burden
Nature Communications
2020
Transfer RNA methyltransferase gene NSUN2 mRNA expression modifies the effect of T cell activation score on patient survival in head and neck squamous carcinoma
Oral Oncology
2020
Re: Ming-Jun Shi, Xiang-Yu Meng, Philippe Lamy, et al. APOBEC-mediated Mutagenesis as a Likely Cause of FGFR3 S249C Mutation Over-representation in Bladder Cancer. Eur Urol 2019;76:9–13
European Urology
2020
Dogs and pigs are transport hosts of Necator americanus : Molecular evidence for a zoonotic mechanism of human hookworm transmission in Ghana
Zoonoses and Public Health
2020
Identifying Modules of Cooperating Cancer Drivers
Unknown Venue
2020
Implementation of Syringe Services Programs to Prevent Rapid Human Immunodeficiency Virus Transmission in Rural Counties in the United States: A Modeling Study
Clinical Infectious Diseases
2019
Inferring Tumor Proliferative Organization from Phylogenetic Tree Measures in a Computational Model
Systematic Biology
2019
Molecular Biology and Evolution of Cancer: From Discovery to Action
Molecular Biology and Evolution
2019
Optimal COVID-19 quarantine and testing strategies
Unknown Venue
2020
Integrative Activity of Mating Loci, Environmentally Responsive Genes, and Secondary Metabolism Pathways during Sexual Development of Chaetomium globosum
mBio
2019
A multigene phylogeny toward a new phylogenetic classification of Leotiomycetes
IMA Fungus
2019
Modelling microbial infection to address global health challenges
Nature Microbiology
2019
GEM-NET: Lessons in Multi-Institution Teamwork Using Collaboration Software
ACS Central Science
2019
The landscape of novel and complementary targets for immunotherapy: an analysis of gene expression in the tumor microenvironment
Oncotarget
2019
Comparative Genomics and Transcriptomics During Sexual Development Gives Insight Into the Life History of the Cosmopolitan Fungus Fusarium neocosmosporiellum
Frontiers in Microbiology
2019
Combined Aurora Kinase A (AURKA) and WEE1 Inhibition Demonstrates Synergistic Antitumor Effect in Squamous Cell Carcinoma of the Head and Neck
Clinical Cancer Research
2019
APOBEC-induced mutations and their cancer effect size in head and neck squamous cell carcinoma
Oncogene
2019
Metabolism and Development during Conidial Germination in Response to a Carbon-Nitrogen-Rich Synthetic or a Natural Source of Nutrition in Neurospora crassa
mBio
2019
Wagging the long tail of drivers of prostate cancer
PLOS Genetics
2019
Optimal Rates for Phylogenetic Inference and Experimental Design in the Era of Genome-Scale Data Sets
Systematic Biology
2018
Evolutionary analyses guide selection of model systems to investigate proto-oncogene function in ALK and LTK
Unknown Venue
2019
Identifying Combinations of Cancer Drivers in Individual Patients
Unknown Venue
2019
Modeling Approaches Toward Understanding Infectious Disease Transmission
Immunoepidemiology
2019
Unmatched level of molecular convergence among deeply divergent complex multicellular fungi
Unknown Venue
2019
Somatic evolutionary timings of driver mutations
BMC Cancer
2018
Effect Sizes of Somatic Mutations in Cancer
JNCI: Journal of the National Cancer Institute
2018
The critical importance of retention in HIV prevention
The Lancet HIV
2018
Using evolutionary genomics, transcriptomics, and systems biology to reveal gene networks underlying fungal development
Fungal Biology Reviews
2018
Developmental Dynamics of Long Noncoding RNA Expression during Sexual Fruiting Body Formation in Fusarium graminearum
mBio
2018
Genomic Comparison Among Global Isolates of L. interrogans Serovars Copenhageni and Icterohaemorrhagiae Identified Natural Genetic Variation Caused by an Indel
Frontiers in Cellular and Infection Microbiology
2018
Neutral Theory and the Somatic Evolution of Cancer
Molecular Biology and Evolution
2018
Heterogeneity and mutation in KRAS and associated oncogenes: evaluating the potential for the evolution of resistance to targeting of KRAS G12C
Oncogene
2018
Analysis of mutation, selection, and epistasis: an informed approach to cancer clinical trials
Oncotarget
2018
CDKN2A Copy Number Loss Is an Independent Prognostic Factor in HPV-Negative Head and Neck Squamous Cell Carcinoma
Frontiers in Oncology
2018
Lvr, a Signaling System That Controls Global Gene Regulation and Virulence in Pathogenic Leptospira
Frontiers in Cellular and Infection Microbiology
2018
Sexual stage-induced long noncoding RNAs in the filamentous fungus Fusarium graminearum
Unknown Venue
2018
Light sensing by opsins and fungal ecology: NOP‐1 modulates entry into sexual reproduction in response to environmental cues
Molecular Ecology
2017
Neutral Theory and the Somatic Evolution of Cancer
Molecular Biology and Evolution
2018
Primary hepatic neuroendocrine carcinoma: report of two cases and literature review
BMC Clinical Pathology
2018
The Cancer Tree
Scientific American
2018
Detection of Regional Variation in Selection Intensity within Protein-Coding Genes Using DNA Sequence Polymorphism and Divergence
Molecular Biology and Evolution
2017
The Moran coalescent in a discrete one-dimensional spatial model
Unknown Venue
2017
Distributions of Mutational Effects and the Estimation of Directional Selection in Divergent Lineages of Arabidopsis thaliana
Genetics
2017
The ancestral levels of transcription and the evolution of sexual phenotypes in filamentous fungi
PLOS Genetics
2017
The likelihood of heterogeneity or additional mutation in KRAS or associated oncogenes to compromise targeting of oncogenic KRAS G12C
Unknown Venue
2017
New insights on the sister lineage of percomorph fishes with an anchored hybrid enrichment dataset
Molecular Phylogenetics and Evolution
2017
PhyloOncology: Understanding cancer through phylogenetic analysis
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
2017
Mutation profiles in early-stage lung squamous cell carcinoma with clinical follow-up and correlation with markers of immune function
Annals of Oncology
2017
Whole-exome sequencing and immune profiling of early-stage lung adenocarcinoma with fully annotated clinical follow-up
Annals of Oncology
2017
A working model of the deep relationships of diverse modern human genetic lineages outside of Africa
Molecular Biology and Evolution
2017
Maximizing Power in Phylogenetics and Phylogenomics: A Perspective Illuminated by Fungal Big Data
Fungal Phylogenetics and Phylogenomics
2017
Oncogenes without a neighboring tumor-suppressor gene are more prone to amplification
Molecular Biology and Evolution
2017
Preface
Fungal Phylogenetics and Phylogenomics
2017
Climatic and evolutionary drivers of phase shifts in the plague epidemics of colonial India
Proceedings of the National Academy of Sciences
2016
One Health approach to cost-effective rabies control in India
Proceedings of the National Academy of Sciences
2016
PhyInformR: phylogenetic experimental design and phylogenomic data exploration in R
BMC Evolutionary Biology
2016
Vaccination strategies against respiratory syncytial virus
Proceedings of the National Academy of Sciences
2016
PathScore: a web tool for identifying altered pathways in cancer data
Bioinformatics
2016
Cost-Effectiveness of Pertussis Vaccination During Pregnancy in the United States
American Journal of Epidemiology
2016
Cost-effectiveness of next-generation vaccines: The case of pertussis
Vaccine
2016
The Fast-Evolving phy-2 Gene Modulates Sexual Development in Response to Light in the Model Fungus Neurospora crassa
mBio
2016
Retrospective Analysis of the 2014–2015 Ebola Epidemic in Liberia
The American Journal of Tropical Medicine and Hygiene
2016
Quantifying Transmission ofClostridium difficilewithin and outside Healthcare Settings
Emerging Infectious Diseases
2016
Determinants of Human African Trypanosomiasis Elimination via Paratransgenesis
PLOS Neglected Tropical Diseases
2016
Early and multiple origins of metastatic lineages within primary tumors
Proceedings of the National Academy of Sciences
2016
The Impact of Enhanced Screening and Treatment on Hepatitis C in the United States
Clinical Infectious Diseases
2015
Optimizing age of cytomegalovirus screening and vaccination to avert congenital disease in the US
Vaccine
2016
A comprehensive phylogeny of birds (Aves) using targeted next-generation DNA sequencing
Nature
2016
Future Perspectives and Challenges of Fungal Systematics in the Age of Big Data
Biology of Microfungi
2016
Genomic and Gene-Expression Comparisons among Phage-Resistant Type-IV Pilus Mutants of Pseudomonas syringae pathovar phaseolicola
PLOS ONE
2015
Quantitative analyses and modelling to support achievement of the 2020 goals for nine neglected tropical diseases
Parasites & Vectors
2015
Utility of characters evolving at diverse rates of evolution to resolve quartet trees with unequal branch lengths: analytical predictions of long-branch effects
BMC Evolutionary Biology
2015
Impact of bed capacity on spatiotemporal shifts in Ebola transmission
Proceedings of the National Academy of Sciences
2015
Inferring the Origin of Metastases from Cancer Phylogenies
Cancer Research
2015
Gene Expression Evolves under a House-of-Cards Model of Stabilizing Selection
Molecular Biology and Evolution
2015
Solving the ecological puzzle of mycorrhizal associations using data from annotated collections and environmental samples - an example of saddle fungi
Environmental Microbiology Reports
2015
Harnessing Case Isolation and Ring Vaccination to Control Ebola
PLOS Neglected Tropical Diseases
2015
Integrating Community-Based Interventions to Reverse the Convergent TB/HIV Epidemics in Rural South Africa
PLOS ONE
2015
Epidemiological and Viral Genomic Sequence Analysis of the 2014 Ebola Outbreak Reveals Clustered Transmission
Clinical Infectious Diseases
2014
Under-reporting and case fatality estimates for emerging epidemics
BMJ
2015
Neural Gene Expression Profiles and Androgen Levels Underlie Alternative Reproductive Tactics in the Ocellated Wrasse,Symphodus ocellatus
Ethology
2014
H-CLAP: hierarchical clustering within a linear array with an application in genetics
Statistical Applications in Genetics and Molecular Biology
2015
Correction: Harnessing Case Isolation and Ring Vaccination to Control Ebola
PLOS Neglected Tropical Diseases
2015
Phylogenetic informativeness reconciles ray-finned fish molecular divergence times
BMC Evolutionary Biology
2014
The peopling of the African continent and the diaspora into the new world
Current Opinion in Genetics & Development
2014
Gene Expression Differences among Three Neurospora Species Reveal Genes Required for Sexual Reproduction in Neurospora crassa
PLoS ONE
2014
Genome-Wide Characterization of Light-Regulated Genes inNeurospora crassa
G3 Genes|Genomes|Genetics
2014
Cellular Superspreaders: An Epidemiological Perspective on HIV Infection inside the Body
PLoS Pathogens
2014
The impact of incorporating molecular evolutionary model into predictions of phylogenetic signal and noise
Frontiers in Ecology and Evolution
2014
Probabilistic uncertainty analysis of epidemiological modeling to guide public health intervention policy
Epidemics
2014
Global Gene Expression and Focused Knockout Analysis Reveals Genes Associated with Fungal Fruiting Body Development in Neurospora crassa
Eukaryotic Cell
2014
Detecting rare gene transfer events in bacterial populations
Frontiers in Microbiology
2014
Optimized primers and other critical conditions for efficient fusion PCR to generate knockout vectors in filamentous fungi.
Fungal Genetics Reports
2013
Sex-linked transcriptional divergence in the hermaphrodite fungusNeurospora tetrasperma
Proceedings of the Royal Society B: Biological Sciences
2013
Epidemiological mechanisms of genetic resistance to kuru
Journal of The Royal Society Interface
2013
Potential Cost-Effectiveness of Schistosomiasis Treatment for Reducing HIV Transmission in Africa – The Case of Zimbabwean Women
PLoS Neglected Tropical Diseases
2013
AuthorReward: increasing community curation in biological knowledge wikis through automated authorship quantification
Bioinformatics
2013
Optimal targeting of seasonal influenza vaccination toward younger ages is robust to parameter uncertainty
Vaccine
2013
Cost-effectiveness of a community-based intervention for reducing the transmission of Schistosoma haematobium and HIV in Africa
Proceedings of the National Academy of Sciences
2013
Yeast response to LA virus indicates coadapted global gene expression during mycoviral infection
FEMS Yeast Research
2013
Response to: The relative utility of sequence divergence and phylogenetic informativeness profiling in phylogenetic study design
Molecular Phylogenetics and Evolution
2013
Evaluating Phylogenetic Informativeness as a Predictor of Phylogenetic Signal for Metazoan, Fungal, and Mammalian Phylogenomic Data Sets
BioMed Research International
2013
Controlling Antimicrobial Resistance through Targeted, Vaccine-Induced Replacement of Strains
PLoS ONE
2012
Reevaluation of Epidemiological Data Demonstrates That It Is Consistent With Cross-Immunity Among Human Papillomavirus Types
Journal of Infectious Diseases
2012
Phylogenetic Signal and Noise: Predicting the Power of a Data Set to Resolve Phylogeny
Systematic Biology
2012
The influence of altruism on influenza vaccination decisions
Journal of The Royal Society Interface
2012
Potential for Rabies Control through Dog Vaccination in Wildlife-Abundant Communities of Tanzania
PLoS Neglected Tropical Diseases
2012
Resampling QTL Effects in the QTL Sign Test Leads to Incongruous Sensitivity to Variance in Effect Size
G3 Genes|Genomes|Genetics
2012
Transcriptome analyses during fruiting body formation in Fusarium graminearum and Fusarium verticillioides reflect species life history and ecology
Fungal Genetics and Biology
2012
Sex-specific gene expression during asexual development of Neurospora crassa
Fungal Genetics and Biology
2012
RBE controls microRNA164 expression to effect floral organogenesis
Development
2012
Differential impact of nutrition on developmental and metabolic gene expression during fruiting body development in Neurospora crassa
Fungal Genetics and Biology
2012
A Test for Selection Employing Quantitative Trait Locus and Mutation Accumulation Data
Genetics
2012
Abundant Gene-by-Environment Interactions in Gene Expression Reaction Norms to Copper within Saccharomyces cerevisiae
Genome Biology and Evolution
2012
Analyses of expressed sequence tags in Neurosporareveal rapid evolution of genes associated with the early stages of sexual reproduction in fungi
BMC Evolutionary Biology
2012
Assessing the Probability of Detection of Horizontal Gene Transfer Events in Bacterial Populations
Frontiers in Microbiology
2012
Codon Deviation Coefficient: a novel measure for estimating codon usage bias and its statistical significance
BMC Bioinformatics
2012
PhyDesign: an online application for profiling phylogenetic informativeness
BMC Evolutionary Biology
2011
Data Integration in Bioinformatics: Current Efforts and Challenges
Bioinformatics - Trends and Methodologies
2011
Phylogenetic informativeness profiling of 12 genes for 28 vertebrate taxa without divergence dates
Molecular Phylogenetics and Evolution
2011
SIR2 and other genes are abundantly expressed in long-lived natural segregants for replicative aging of the budding yeast Saccharomyces cerevisiae
FEMS Yeast Research
2011
Taxon Sampling and the Optimal Rates of Evolution for Phylogenetic Inference
Systematic Biology
2011
Tasting Soil Fungal Diversity with Earth Tongues: Phylogenetic Test of SATé Alignments for Environmental ITS Data
PLoS ONE
2011
Retrospective evidence for a biological cost of vancomycin resistance determinants in the absence of glycopeptide selective pressures
Journal of Antimicrobial Chemotherapy
2011
Getting the Most Out of Your Fungal Microarray Data: Two Cost- and Time-Effective Methods
Methods in Molecular Biology
2011
Northern species of earth tongue genus Thuemenidium revisited, considering morphology, ecology and molecular phylogeny
Mycologia
2010
LOX: inferring Level Of eXpression from diverse methods of census sequencing
Bioinformatics
2010
Optimal Selection of Gene and Ingroup Taxon Sampling for Resolving Phylogenetic Relationships
Systematic Biology
2010
Identification of new molecular markers for assembling the eukaryotic tree of life
Molecular Phylogenetics and Evolution
2010
The filamentous fungal gene expression database (FFGED)
Fungal Genetics and Biology
2010
Multi-targeted priming for genome-wide gene expression assays
BMC Genomics
2010
Evolving gene expression: from G to E to G×E
Trends in Ecology & Evolution
2009
<I>Geoglossomycetes</I> cl. nov., <I>Geoglossales</I> ord. nov. and taxa above class rank in the <I>Ascomycota</I> Tree of Life
Persoonia - Molecular Phylogeny and Evolution of Fungi
2009
Maximum-Likelihood Model Averaging To Profile Clustering of Site Types across Discrete Linear Sequences
PLoS Computational Biology
2009
Factors affecting the reversal of antimicrobial-drug resistance
The Lancet Infectious Diseases
2009
Evolution of Reproductive Morphology in Leaf Endophytes
PLoS ONE
2009
Measuring Transcription Factor–Binding Site Turnover: A Maximum Likelihood Approach Using Phylogenies
Genome Biology and Evolution
2009
Article Commentary: Snapshots of Tree Space
Evolutionary Bioinformatics
2009
RNA extraction, probe preparation, and competitive hybridization for transcriptional profiling using Neurospora crassa long-oligomer DNA microarrays
Fungal Genetics Reports
2008
The Phylogenetic Informativeness of Nucleotide and Amino Acid Sequences for Reconstructing the Vertebrate Tree
Journal of Molecular Evolution
2008
Bringing Web 2.0 to bioinformatics
Briefings in Bioinformatics
2008
HCLS 2.0/3.0: Health care and life sciences data mashup using Web 2.0/3.0
Journal of Biomedical Informatics
2008
Sleuthing the difference a nucleotide can make
Molecular Ecology
2008
Quantifying variation in gene expression
Molecular Ecology
2007
Enabling a Community to Dissect an Organism: Overview of the Neurospora Functional Genomics Project
Fungal Genomics
2007
Phase-specific gene expression underlying morphological adaptations of the dimorphic human pathogenic fungus, Coccidioides posadasii
Fungal Genetics and Biology
2006
Population structure and gene evolution inSaccharomyces cerevisiae
FEMS Yeast Research
2006
Ecological and evolutionary genomics of Saccharomyces cerevisiae
Molecular Ecology
2006
Long-oligomer microarray profiling in Neurospora crassa reveals the transcriptional program underlying biochemical and physiological events of conidial germination
Nucleic Acids Research
2005
Concerted Evolution in the Repeats of an Immunomodulating Cell Surface Protein, SOWgp, of the Human Pathogenic Fungi Coccidioides immitis and C. posadasii
Genetics
2005
A Bayesian method for analysing spotted microarray data
Briefings in Bioinformatics
2005
Designing Experiments Using Spotted Microarrays to Detect Gene Regulation Differences Within and Among Species
Methods in Enzymology
2005
Monitoring and modeling horizontal gene transfer
Nature Biotechnology
2004
Mitochondrial genome size variation in New World and Old World populations of Drosophila melanogaster
Heredity
2004
Monitoring horizontal gene transfer
Nature Biotechnology
2004
Population Genetic Variation in Genome-Wide Gene Expression
Molecular Biology and Evolution
2003
Pathway Processor: A Tool for Integrating Whole-Genome Expression Results into Metabolic Networks
Genome Research
2002
Manifold anomalies in gene expression in a vineyard isolate of Saccharomyces cerevisiae revealed by DNA microarray analysis
Proceedings of the National Academy of Sciences
2000
Solvent Accessibility and Purifying Selection Within Proteins of Escherichia coli and Salmonella enterica
Molecular Biology and Evolution
2000
Gene expression profiling in evolutionary genetics
The Evolution of Population Biology
2004
Radiation-Specific Clinical Data Should Be Included in Existing Large-Scale Genomic Datasets
International Journal of Radiation Oncology*Biology*Physics
2017

Education

Harvard University

Ph.D., Organismic and Evolutionary Biology / May, 2002

Cambridge, Massachusetts, United States of America

Brown University

Sc.B., Biology / May, 1994

Providence, Rhode Island, United States of America

Experience

Yale University

Professor / July, 2018Present

Elihu Professor of Biostatistics / July, 2018Present

Elihu Associate Professor of Biostatistics / July, 2017June, 2018

Associate Professor / July, 2013June, 2018

Associate Professor / July, 2013June, 2017

Assistant Professor / July, 2006June, 2013

University of Connecticut

Assistant Professor / August, 2004May, 2006

St. Ann's School

Teacher / September, 1994June, 1997

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