Alexa Lampasona, Ph.D.

Project manager/ Senior Research scientist with expertise in the fields of cell therapies, gene therapies, and neuroscience.

Research Expertise

Geriatrics and Gerontology
Neurology (clinical)
Aging
Developmental Biology
Molecular Biology

About

**For my doctoral thesis at Stony Brook University, I investigated how a protein called Hnrnpab regulates brain development and function. This protein binds RNA and is highly enriched in regions of the brain where self-renewing stem cells reside. Neural stem cells can divide and differentiate into any cell typically found in the brain. These cells also can migrate to different regions of brain injury to aid in the healing process, and my thesis project investigated the role Hnrnpab played in this process. Part of my responsibility in the lab was to design experiments and mentor undergraduate students, providing valuable scientific support and management to their projects.** **During my postdoctoral research at the University of Massachusetts Medical School, I studied how mutations in a gene called C9orf72 gene can cause Amyotrophic Lateral Sclerosis (ALS). The causative mutation in C9orf72 ALS is a repeat expansion within the intron and when these repeats are translated into protein, they are highly toxic and can disrupt motor neuron cell function, ultimately causing motor neuron cell death. I was responsible for designing and performing experiments to understand how these proteins are synthesized from the intron. I was also involved in managing thesis projects for several PhD students.**  **As a senior scientist at HebeCell, I collaborated with QA and QC professionals to conceptualize, author, and perform SOPs to produce immuno-oncology cell therapies. Our goal was to engineer natural killer (NK) immune cells to kill tumors. To achieve this, we differentiated NK cells from stem cells to generate “off-the-shelf” cell therapies against cancer.**   **As a project manager/ senior research scientist for cell and gene therapy at Creative Biolabs, I manage scientific research projects for clients worldwide.** <br>

Legacy Map

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Education

Stony Brook University

Ph.D., Molecular and Cellular Pharmacology / August, 2018

Stony Brook, New York, United States of America

Manhattan College

Bachelor of Science, Biology / May, 2013

New York, New York, United States of America

Experience

Creative Biolabs

Project Manager/ Research Scientist / September, 2022Present

At Creative Biolabs, I manage client projects in the fields of cell and gene therapy, from, design, SOW generation, and data reporting. I am also responsible for learning about novel technologies quickly to serve our clients, as well as maintain broad knowledge of all products and services offered.

HebeCell

Senior Scientist / April, 2021August, 2021

At HebeCell, I was responsible for producing CAR-NK cells through genetic engineering of iPSCs to generate off-the-shelf immuno-oncology cell therapies. I also conceptualized, authored, and performed SOPs for GLP QC assays for release criteria for NK cell therapy.

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