Amir Manbachi

Co-director and Founder of the Johns Hopkins HEPIUS Innovation Lab

Research Expertise

Biomedical Engineering
Engineering Design
Medical Devices
Ultrasound
Neurosurgery
Radiology, Nuclear Medicine and imaging
Radiological and Ultrasound Technology
Mechanical Engineering
Mechanics of Materials
Biochemistry
Bioengineering
Biomaterials
Biotechnology
Neurology (clinical)
Surgery
Orthopedics and Sports Medicine
Health, Toxicology and Mutagenesis
Medical Laboratory Technology
Toxicology
Pharmaceutical Science
Physiology (medical)
Physiology
Biophysics
Molecular Biology
Acoustics and Ultrasonics
Otorhinolaryngology
Cardiology and Cardiovascular Medicine
Public Health, Environmental and Occupational Health
Cancer Research
Oncology
Neurology
Rehabilitation

Legacy Map

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Publications

Nanotechnology in Textiles
ACS Nano
2016
Microfabricated Biomaterials for Engineering 3D Tissues
Advanced Materials
2012
Development and Application of Piezoelectric Materials for Ultrasound Generation and Detection
Ultrasound
2011
Microfluidics-Enabled Multimaterial Maskless Stereolithographic Bioprinting
Advanced Materials
2018
Cardiovascular Organ-on-a-Chip Platforms for Drug Discovery and Development
Applied In Vitro Toxicology
2016
Sonolucent Cranial Implants
Journal of Craniofacial Surgery
2019
Three-dimensional assessment of robot-assisted pedicle screw placement accuracy and instrumentation reliability based on a preplanned trajectory
Journal of Neurosurgery: Spine
2020
Transcranioplasty Ultrasound Through a Sonolucent Cranial Implant Made of Polymethyl Methacrylate
Journal of Craniofacial Surgery
2019
Minimally invasive therapeutic ultrasound: Ultrasound-guided ultrasound ablation in neuro-oncology
Ultrasonics
2020
Virtual fluoroscopy for intraoperative C-arm positioning and radiation dose reduction
Journal of Medical Imaging
2018
Intraoperative ultrasound to monitor spinal cord blood flow after spinal cord injury
Medical Imaging 2020: Biomedical Applications in Molecular, Structural, and Functional Imaging
2020
Ultrasound Physics
Practical Medical Physics
2021
Improved Treatment of Postpartum Hemorrhage: Design, Development, and Bench-Top Validation of a Reusable Intrauterine Tamponade Device for Low-Resource Settings
Journal of Medical Devices
2020
Characterization of Common Carotid Artery Curvature and Its Impact on Velocity Profile Shape
ASME 2010 Summer Bioengineering Conference, Parts A and B
2010
Ultrasound monitoring of microcirculation: An original study from the laboratory bench to the clinic
Microcirculation
2022
Advances in monitoring for acute spinal cord injury: a narrative review of current literature
The Spine Journal
2022
USDL: Inexpensive Medical Imaging Using Deep Learning Techniques and Ultrasound Technology
2020 Design of Medical Devices Conference
2020
Minimizing cotton retention in neurosurgical procedures: which imaging modality can help?
Medical Imaging 2020: Biomedical Applications in Molecular, Structural, and Functional Imaging
2020
High-intensity focused ultrasound for medical therapy
Power Ultrasonics
2015
Porcine Model of Spinal Cord Injury: A Systematic Review
Neurotrauma Reports
2022
Social Non-profit Bioentrepreneurship: Current Status and Future Impact on Global Health
Frontiers in Public Health
2021
Minimizing Cotton Ball Retention in Neurological Procedures
2020 Design of Medical Devices Conference
2020
12. Angiotensin-II type-1 receptor blockade decreased T2 signal intensity in spinal cord compression in symptomatic cervical spondylotic myelopathy
The Spine Journal
2019
Ultrasound Imaging Radial Array: Design and Fabrication
Towards Ultrasound-guided Spinal Fusion Surgery
2016
Low-Intensity Pulsed Ultrasound Neuromodulation of a Rodent's Spinal Cord Suppresses Motor Evoked Potentials
IEEE Transactions on Biomedical Engineering
2023
Towards A Universal Device for Point-of-Care Medicine: A Custom Transducer for Long-Term Monitoring of Local Vascular Flow Via Ultrasound Imaging
2022 Design of Medical Devices Conference
2022
Johns Hopkins Hospital
Brain Fever
2021
Design of an Ultrasound Probe Holder to Minimize Motion Artifact During Sonography
2021 Design of Medical Devices Conference
2021
The Design and Use of a Minimally-Invasive, Expandable Retractor for Deep-Seated Brain Lesions
2021 Design of Medical Devices Conference
2021
A Miniature Laser Speckle Contrast Imager for Monitoring the Neuromodulatory Effect of Transcranial Ultrasound Stimulation
2021 Design of Medical Devices Conference
2021
Automatic detection of cotton balls during brain surgery: where deep learning meets ultrasound imaging to tackle foreign objects
Medical Imaging 2021: Ultrasonic Imaging and Tomography
2021
The development of Smart Hospital Assistant: integrating artificial intelligence and a voice-user interface for improved surgical outcomes
Medical Imaging 2021: Imaging Informatics for Healthcare, Research, and Applications
2021
Development of Voice-Controlled Smart Surgical Bed
2020 Design of Medical Devices Conference
2020
Reusable Core Needle Biopsy Device for Low-Resource Settings
Journal of Global Oncology
2018
Bioprinting: Microfluidics-Enabled Multimaterial Maskless Stereolithographic Bioprinting (Adv. Mater. 27/2018)
Advanced Materials
2018
Clinical Translation of the LevelCheck Algorithm for Automatic Localization of Target Vertebrae in Spine Surgery
The Spine Journal
2017
Towards Ultrasound-guided Spinal Fusion Surgery
Springer Theses
2016
Disruption of the Blood-Spinal Cord Barrier using Low-Intensity Focused Ultrasound in a Rat Model
Journal of Visualized Experiments
2023
Sonodynamic Therapy for the Treatment of Glioblastoma Multiforme in a Mouse Model Using a Portable Benchtop Focused Ultrasound System
Journal of Visualized Experiments
2023
FlowMorph: Morphological Segmentation of Ultrasound-Monitored Spinal Cord Microcirculation
2022 IEEE Biomedical Circuits and Systems Conference (BioCAS)
2022
Design of a Custom Flexible Ultrasound Transducer as an Implantable Cranial Sensor for Long-Term Post-Operative Monitoring of Brain Tumor Regrowth
2022 IEEE International Ultrasonics Symposium (IUS)
2022
Applications of elastography in operative neurosurgery: A systematic review
Journal of Clinical Neuroscience
2022
Design and Development of Smart Surgical Assistant Technologies
Unknown Venue
2022
Designing an Accurate Benchtop Characterization Device: An Acoustic Measurement Platform for Localizing and Implementing Therapeutic Ultrasound Devices and Equipment (Amplitude)
2022 Design of Medical Devices Conference
2022
Designing a Murine Model of Human Glioblastoma Brain Tumor: Development of a Platform for Validation Using Ultrasound Elastography
2022 Design of Medical Devices Conference
2022
Design and Development of System Components for Therapeutic Ultrasound Devices: Enhancing Focused Ultrasound Treatments Using Cones with Clinical and Ergonomic Considerations
2022 Design of Medical Devices Conference
2022
513 Towards Obtaining One Billion Recordings Per Cubic Millimeter for the Validation of Focused Ultrasound Transducers: How Can Robust Systems Help With Translational Activities?
Journal of Clinical and Translational Science
2022
524 How Can I Provide My Patient Insights in a Nontraditional Advocacy Role?
Journal of Clinical and Translational Science
2022
216 An Example for Establishing a Clinically Translational Innovation Lab at a University Setting
Journal of Clinical and Translational Science
2022
In Reply: Ultrasound in Traumatic Spinal Cord Injury: A Wide-Open Field
Neurosurgery
2021
Towards standardization of the parameters for opening the blood–brain barrier with focused ultrasound to treat glioblastoma multiforme: A systematic review of the devices, animal models, and therapeutic compounds used in rodent tumor models
Frontiers in Oncology
2023
Automatic detection of foreign body objects in neurosurgery using a deep learning approach on intraoperative ultrasound images: From animal models to first in-human testing
Frontiers in Surgery
2022
Design and Fabrication of a Focused Ultrasound Device for Minimallyinvasive Neurosurgery: Reporting a Second, Miniaturized and Mrcompatible Prototype with Steering Capabilities
2021 Design of Medical Devices Conference
2021
90449 Can Ultrasound detect changes to spinal cord blood flow before and after injury?
Journal of Clinical and Translational Science
2021
Toward Minimally Invasive Therapeutic Ultrasound: Ultrasound-guided Ablation in Neuro-oncology
Unknown Venue
2020
Development of a Portable Blood Potassium Monitoring Device for Dialysis Patients
2020 Design of Medical Devices Conference
2020
An Evaluation of Sensing Technologies to Measure Intraoperative Leg Length for Total Hip Arthroplasty
2020 Design of Medical Devices Conference
2020
A Novel Intermediate Attachment to Reduce Contamination in Reusable Core Needle Biopsy Devices
Journal of Medical Devices
2020
3D printed cardiovascular patient specific phantoms used for clinical validation of a CT-derived FFR diagnostic software
Medical Imaging 2018: Biomedical Applications in Molecular, Structural, and Functional Imaging
2018
Second Joint EMBS-BMES Conference 2002 - Engineering in Medicine and Biology Society Annual Fall Meeting of the Biomedical Engineering Society
Proceedings of the Second Joint 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society] [Engineering in Medicine and Biology
2002
A finite element model to assess distal radius fracture stability
Proceedings of the Second Joint 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society] [Engineering in Medicine and Biology
Therapeutic Ultrasound Applications in Neurosurgery
The Abundant Promise of Ultrasound in Neurosurgery: A Broad Overview and Thoughts on Ethical Paths to Realizing Its Benefits
2022
SHEAR STRESS AND CELL DOCKING INSIDE MICROFLUIDIC SYSTEMS: A COMPUTATIONAL AND EXPERIMENTAL STUDY
Journal of Biomechanics
2008
Applications of Focused Ultrasound for the Treatment of Glioblastoma: A New Frontier
Cancers
2022
Ultrasound in Traumatic Spinal Cord Injury: A Wide-Open Field
Neurosurgery
2021
Epidural Oscillating Cardiac-Gated Intracranial Implant Modulates Cerebral Blood Flow
Neurosurgery
2020
Curricular Advancement of Biomedical Engineering Undergraduate Design Projects Beyond 1 Year: A Pilot Study
Annals of Biomedical Engineering
2019
Correction to: Curricular Advancement of Biomedical Engineering Undergraduate Design Projects Beyond 1 Year: A Pilot Study
Annals of Biomedical Engineering
2019
Flexible piezoelectric sensor for real-time image-guided colonoscopies: a solution to endoscopic looping challenges in clinic
Medical Imaging 2020: Image-Guided Procedures, Robotic Interventions, and Modeling
2020
Infrared image-guidance for intraoperative assessment of limb length discrepancy during total hip arthroplasty procedures
Medical Imaging 2020: Image-Guided Procedures, Robotic Interventions, and Modeling
2020
The effect of renin-angiotensin system blockers on spinal cord dysfunction and imaging features of spinal cord compression in patients with symptomatic cervical spondylosis
The Spine Journal
2020
Minimally invasive intraventricular ultrasound: design and instrumentation towards a miniaturized ultrasound-guided focused ultrasound probe
Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling
2019
Starting a Medical Technology Venture as a Young Academic Innovator or Student Entrepreneur
Annals of Biomedical Engineering
2017
A line fiducial method for geometric calibration of cone-beam CT systems with diverse scan trajectories
Physics in Medicine & Biology
2018
Clinical Translation of the LevelCheck Decision Support Algorithm for Target Localization in Spine Surgery
Annals of Biomedical Engineering
2018
Design and validation of an open-source library of dynamic reference frames for research and education in optical tracking
Journal of Medical Imaging
2018
Technical note: design and validation of an open-source library of dynamic reference frames for research and education in optical tracking
Medical Imaging 2018: Image-Guided Procedures, Robotic Interventions, and Modeling
2018
C-arm positioning using virtual fluoroscopy for image-guided surgery
SPIE Proceedings
2017
Planning, guidance, and quality assurance of pelvic screw placement using deformable image registration
Physics in Medicine & Biology
2017
Surface acoustic waves induced micropatterning of cells in gelatin methacryloyl (GelMA) hydrogels
Biofabrication
2017
Bioprinted thrombosis-on-a-chip
Lab on a Chip
2016
Design and fabrication of a low-frequency (1-3 MHz) ultrasound transducer for accurate placement of screw implants in the spine
SPIE Proceedings
2014
Guided pedicle screw insertion: techniques and training
The Spine Journal
2014
On estimating the directionality distribution in pedicle trabecular bone from micro-CT images
Physiological Measurement
2014
Slow and fast ultrasonic wave detection improvement in human trabecular bones using Golay code modulation
The Journal of the Acoustical Society of America
2012
On the shape of the common carotid artery with implications for blood velocity profiles
Physiological Measurement
2011
A computational and experimental study inside microfluidic systems: the role of shear stress and flow recirculation in cell docking
Biomedical Microdevices
2010
High-throughput screening of cell responses to biomaterials
European Journal of Pharmaceutical Sciences
2008
Microcirculation within grooved substrates regulates cell positioning and cell docking inside microfluidic channels
Lab on a Chip
2008
A Gradient-generating Microfluidic Device for Cell Biology
Journal of Visualized Experiments
2007
A Microfluidic Device with Groove Patterns for Studying Cellular Behavior
Journal of Visualized Experiments
2007

Education

Harvard-MIT Division of Health Sciences and Technology

Post-doctoral fellowship, Harvard-MIT Division of Health Sciences and Technology: Cambridge, MA, United States

Cambridge, Massachusetts, United States of America

University of Toronto

Ph.D., Institute for Biomaterials and Biomedical Engineering / June, 2015

Toronto, Ontario, Canada

University of Toronto

Masters of Applied Science, Institute for Biomaterials and Biomedical Engineering / June, 2010

Toronto, Ontario, Canada

University of Toronto Faculty of Applied Science and Engineering

Bachelor of Applied Science, Engineering Science / June, 2008

Toronto, Ontario, Canada

Experience

Johns Hopkins University

Faculty Member / May, 2016Present

University of Toronto

Researcher / August, 2008Present

Stryker Leibinger GmbH and Company KG

Research and Development Engineering Intern / April, 2012September, 2012

Harvard-MIT Division of Health Sciences and Technology

Research Assistant / May, 2007September, 2007

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