Dr. Brent Lindquist-Kleissler, Ph.D.

Ph.D. in bioinorganic chemistry with publications on inorganic synthesis, computational chemistry, and crystallography.

Research Expertise

Main-group inorganic chemistry

About

Dr. Brent Lindquist-Kleissler received his PhD in Chemistry from the University of California Santa Cruz in 2023. During his graduate studies, he focused on bioinorganic chemistry and developed new methodologies for the synthesis and characterization of antimony-containing molecules. His computational research on antimony-containing molecules provided new insight to understanding main-group chemical structures and bonding. Prior to completing his doctorate, Dr. Lindquist-Kleissler worked as a compounding manager at Rivergate Pharmacy, where he gained experience in formulating customized medications for patients. During his undergraduate studies he studied natural product synthesis at Fort Lewis College and at Northeastern University, where he synthesized new drug delivery systems. Dr. Lindquist-Kleissler's expertise in both inorganic chemistry, computational chemistry, organic chemistry, and pharmaceuticals allows him to bridge the gap between the laboratory and the pharmacy, ensuring the safe and effective use of medications for patients. He is passionate about finding innovative solutions to improve patient health and is committed to staying current on the latest advancements in the field. In his free time, Dr. Lindquist-Kleissler enjoys hiking, playing tennis, and reading.

Publications

Analysis of Oxygen–Pnictogen Bonding with Full Bond Path Topological Analysis of the Electron Density

Inorganic Chemistry

2021

Geometry of Pentaphenylantimony in Solution: Support for a Trigonal Bipyramidal Assignment from X-ray Absorption Spectroscopy and Vibrational Spectroscopic Data

Inorganic Chemistry

2021

Models of the putative antimony(v)–diolate motifs in antileishmanial pentavalent antimonial drugs

Dalton Transactions

2023

Synthesis of a C-7 Pd-glycosyl-donor via the base promoted alkylative CO2 trapping with 2-acetylfuran

Journal of CO2 Utilization

2021

Chemical Structure Elucidation in the Development of Inorganic Drugs: Evidence from Ru‐, Au‐, As‐, and Sb‐based Medicines

European Journal of Inorganic Chemistry

2024

Education

University of California Santa Cruz

PhD, Chemistry

Santa Cruz, California, United States of America

Fort Lewis College

Bachelor of Science, Chemistry / May, 2017

Durango, Colorado, United States of America

Experience

University of California Santa Cruz

Graduate Student / August, 2018 — December, 2023

Developed a more information-rich topological analysis of pnictogen-oxygen bonding using DFT and QTAIM. Solved the long outstanding question of the solution-state geometry of pentaphenylantimony using Sb XAS, Raman spectroscopy, single-crystals XRD, and TD-DFT. Synthesized and characterized a small library of novel compounds designed to model antimony-containing drugs using multidimensional and multinuclear NMR, HPLC, single-crystal XRD, DFT, and ab initio molecular dynamics.

Rivergate Pharmacy

Compounding Manager / June, 2017 — June, 2018

Optimized the workflow and doubled productivity in preparing prescription creams, capsules, troches, and suspensions increasing sales and number of patients helped. Managed the compounding operations of the pharmacy and increased efficiency of chemical ordering and new formula creation.

Northeastern University

Research Associate / June, 2015 — August, 2015

Synthesized the natural product SIA7248 and optimized the conditions of an allylation reaction. Successfully showed metal-catalyst interactions play a role in Leighton's allylations, furthering fundamental knowledge of organic synthetic pathways.

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